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다음증을 동반한 정신분열증 환자에서 항콜린성 약물 복용 중 발생한 만성 신부전 1례
전일영 ( Il Young Chon ),오동준 ( Dong Joon Oh ),최승진 ( Seung Jin Choi ),김지영 ( Ji Young Kim ),안계련 ( Ke Ryun Ahn ),이원준 ( Won Joon Lee ),이지연 ( Ji Yeon Lee ),백혜리 ( Hae Ri Baek ),이은지 ( Eun Ji Lee ),한상원 ( Sang Wo 대한신장학회 2009 Kidney Research and Clinical Practice Vol.28 No.6
Anticholinergic drugs block muscarinic receptors at the detrusor muscle of the bladder. It can cause urinary retention by contracting the bladder neck. Cases of hydronephrosis, bladder dilatation as a result of polydipsia while taking anticholinergic drugs have been reported, but very few cases of chronic renal failure can be found. We report a case of a polydipsic schizophrenic patient who, after taking anticholinergic drugs as antipsychotic drugs to treat his schizophrenia for a long time, presented with chronic renal failure due to functional obstructive uropathy in the absence of demonstrable anatomic causes of obstruction.
조소영 ( So Young Jo ),김나영 ( Nayoung Kim ),이정원 ( Jung Won Lee ),임지환 ( Ji Hwan Lim ),최치언 ( Chiun Choi ),전일영 ( Il Young Chon ),길호 ( Ho Kil ),민보영 ( Bo Young Min ),변영상 ( Young Sang Byoun ),이반석 ( Ban Seok Lee 대한소화기학회 2012 대한소화기학회지 Vol.59 No.6
Background/Aims: The aim of this study was to compare polyethylene glycol (PEG) 4 L, split method of PEG 4 L and PEG 2 L plus sodium phosphate (NaP) in the aspect of bowel preparation quality, safety, patients` compliance and preference. Methods: Total 249 subjects were prospectively enrolled and received bowel preparation for colonoscopy from August to October in 2010; PEG 4 L (93 subjects), split method of 4 L PEG (74 subjects) and PEG 2 L plus NaP 90 mL group (82 subjects). To investigate the completion, preference for bowel preparation and safety, a questionnaire survey was conducted before colonoscopy. Results: There were no significant intergroup differences in the aspect of completion of preparation, cecal intubation time and success rate. Satisfaction and preference were higher in PEG 2 L plus NaP 90 mL and split method of 4 L PEG compared with PEG 4 L. In the aspect of the bowel preparation quality PEG 4 L showed significantly higher quality in the morning colonoscopy (p<0.001). However, in the afternoon colonoscopy PEG 2 L plus NaP 90 mL showed better result than PEG 4 L (p=0.009). Hyperphosphatemia was most frequently observed in PEG 2 L plus NaP 90 mL, but no severe adverse events occurred (p<0.001). Conclusions: PEG 4 L showed better result than split method of 4 L PEG or PEG 2 L plus NaP 90 mL in the aspect of bowel preparation quality and safety. (Korean J Gastroenterol 2012;59:414-422)
김석영 ( Seok Young Kim ),이형석 ( Hyung Suk Lee ),김소미 ( So Mi Kim ),이원준 ( Won Jun Lee ),이지연 ( Ji Yeon Lee ),최승진 ( Seung Jin Choi ),전일영 ( Il Young Chon ),이현정 ( Hyun Jeong Lee ) 대한소화기학회 2008 대한소화기학회지 Vol.51 No.1
Actinomycosis is an indolent, slowly progressive infection caused by Actinomyces species and usually results in the formation of characteristic clumps called sulfur granules. Depending on the site of primary infection, it is generally classified as cervicofacial, thoracic, and abdominal type. Abdominal actinomycosis is often difficult to diagnose before operation because of its infrequent and chronic disease progression without any characteristic clinical features. In principle, diagnosis is based on histologic demonstration of sulfur granules in pus or surgically resected specimen, and the treatment consists of long-term antibiotic therapy coupled with or without surgical resection. We report a case of abdominal actinomycosis presenting as mesenteric mass adhering to small bowel confirmed by laparoscopic exploration and biopsy. Treatment with intravenous penicillin for 4 weeks followed by additional oral therapy for 11 months resulted in clinical resolution. (Korean J Gastroenterol 2008;51:48-51)