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뇌졸중 환자군의 Warfarin Nomogram 설정을 위한 실제 처방전 평가
장주영,고경미,윤지연,한옥연,임성실,Jang, Ju-Young,Ko, Kyung-Mi,Yoon, Ji-Yeon,Han, Ok-Yeon,Lim, Sung-Cil 대한약학회 2009 약학회지 Vol.53 No.2
Warfarin is the most widely used oral anticoagulant in the world but maintenance of proper therapeutic range and prevention of adverse drug events always need to be careful. Especially, in Korea, warfarin dosing for patients with cerebral infarction is currently based on the nomogram which is done by foreign clinical trials not for the Korean. Therefore we evaluate warfarin dose of patients in the neurology and eventually get the base data of warfarin nomogram for Korean with stroke. We performed this study retrospectively on reviewing the medical charts to evaluate the prescribed loading dose (LD) and maintenance dose (MD) of warfarin and each responding International Normalized Ratio (INR) with any bleeding adverse drug reaction including of patient's characteristics for total 75 patients with stroke in the department of neurology of Kangnam ST. Mary's Hospital from January 2005 to June 2008. All evaluated patients should not be treated with warfarin in the past at all and should be initiated warfarin therapy first.ly at this time. All evaluated patients were divided as two classes by wafarin LD which is; 1) HDG - a high loading dosing group prescribed over 5mg, and 2) LDG - a low loading dosing group prescribed 5mg or below. As a result, average LD was $9.34{\pm}0.22$ mg (p=0.000) in HDG and $4.25{\pm}0.39$ mg (p=0.000) in LDG. Average baseline INR was $0.91{\pm}0.05$ (p=0.161) in HDG and $1.26{\pm}0.14$ (p=0.002) in LDG. On the first and second week, daily MD was $4.21{\pm}0.14$ mg (p=0.000) and $2.96{\pm}0.19$ mg (p=0.696) in HDG and also in LDG, $2.95{\pm}0.29$ mg (p=0.000) and $3.14{\pm}0.36$ mg (p=0.696). Also average reacting daily INR was respectively $2.53{\pm}0.12$ (p=0.141) and $2.51{\pm}0.16$ (p=0.678) in HDG, and in LDG, $2.11{\pm}0.17$ (p=0.141) and $2.42{\pm}0.14$ (p=0.678). After the second week, INR was not measured in regularly. Also most of underlying diseases were hypertension (n=38), diabetes mellitus (n=14), dyslipidemia (n=8) in order. Four ADRs with simple hemorrhage were occurred and those were due to drug interaction by comedication. In the conclusion, proper starting LD for Korean with stroke is 10 mg if baseline INR is around 1.0 or 5 mg if over 1.3. Proper MD need to be more evaluated in the future for setting up warfarin nomogram to make prospective study.
용융탄산염 발전용 연료전지 3㎿급 EBOP 시스템 현장 실증
장주영(Ju-Young Jang),정우택(Woo-Taek Joung),이정흠(Jeong-Hum Lee),문상호(Sang-Ho Moon) 전력전자학회 2011 전력전자학술대회 논문집 Vol.2011 No.7
EBOP(Electrical Balance of Plant)는 연료전지 출력인 DC 전원을 전력변환기술을 이용하여 계통 전원에 연계하는 계통 연계 인버터 시스템이다. 포스코파워에서 개발한 3㎿급 EBOP 시스템은 국제 규격(IEEE std.1547, UL1741)에 의한 성능 검증 시험을 거치고 국내 2개 현장에 5기를 적용하여 운전 중이다.
도시구조에서 합리주의 건축과 기념비적 건축의 상관관계에 대한 연구 - 역사성과 축을 중심으로 -
장주영(Jang, Ju-Young),원호성(Won, Ho-sung) 대한건축학회 2022 대한건축학회 학술발표대회 논문집 Vol.42 No.1
Reckless urban development due to rapid urbanization creates cities without identity. In the future, it is necessary to create a new behavioral urban structure in consideration of historical characteristics, regional characteristics, topographical characteristics, and relationships with surrounding areas to form an urban image. In this study, we look for the basic contents of urban structure in Italian rationalism in the past. In addition, the correlation is derived through examples of buildings by representative architects, focusing on the common characteristics of monumental architecture and rationalism that lead to urban growth and infrastructure construction.
정밀 토크 제어를 위한 SMPM 전동기의 약자속 영역에서 자기 돌극성 추정
장주영(Ju-Young Jang),최찬희(Chan-Hee Choi),석줄기(Jul-Ki Seok) 한국조명·전기설비학회 2009 조명·전기설비학회논문지 Vol.23 No.8
본 논문에서는 고속에서 토크 제어 시 표면 부착형 전동기에 발생되는 자기 포화 현상으로 인한 돌극 현상을 분석하고 해석한다. 인덕턴스 추정을 위한 State-Filter를 고안하여 d축과 q축의 임피던스를 추정하며 추정된 d축과 q축의 임피던스 차이로 자기 포화로 인한 돌극성이 존재한다는 것을 증명한다. 또한, 약자속 영역에서 토크 제어를 수행함에 있어서 돌극성 효과를 고려한 전류제어 방법을 제안한다. 릴럭턴스 토크를 가지는 전동기 모델을 기반으로 하여 제안된 제어기는 전류 제한원에서 토크 곡선을 따라 d축과 q축의 전류를 조절한다. 제안된 전류제어의 타당성을 증명하기 위해 600[W] 상용 SMPM 전동기를 대상으로 실험을 수행하였다. The magnetic saliency effect in surface-mounted permanent-magnet (SMPM) motors on the torque control at high speeds is first presented and analyzed in this paper. The d- and q- axes impedance are measured by proposed State-Filter. Measurement of the d- and q- axes impedance difference is performed to prove the existence of the magnetic saliency. Then, the saliency effects on the torque control performance in the flux weakening region are discussed. Based on the developed motor modeling with the reluctance torque, the proposed control adjusts the d- and q-axis current toward the operating point to track the commanded torque. The feasibility of the presented idea is verified by experimental results on a commercial 600[W] SMPM motor.