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성인의 후두유두종에 대한 Human Papillomavirus의 DNA Typing
유장렬,임영묵,장문수 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2
A study is reported in which an in situ hybridization technique for the demonstration of human papillomavirus has been applied to formalin-fixed paraffin processed tissue obtained from thirteen patients with adult laryngeal papilloma. Nine patients were positive for HPV 6, five of these were positive for HPV 11. All cases were negative for HPV 16 and 18. As above results, laryngeal papilloma are closely related to HPV 6 and 11.
박찬일,임영묵 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2
Otitis media with cholesteatoma in children is more aggressive but has a fewer complications than in adults. A clinical anaylsis was performed in 47 ears of 43 children under 15 years of age who had undergone tympanomastoidectomy at Department of Otolarynology, Chungnam National University Hospital from Aug. 1981 to Sep. 1992. Bilateral otitis media with cholesteatoma was noted in 8 cases, and otorrhea was the most common symptom. Ear drum perforation was most common on attic (59.6%) and posterosuperior portion (21.3%). Preoperative complications were noted in 12 ears (25.5%) ; subperiosteal abscess in 10.7%, deaf in 8.5%, facial nerve paralysis in 2.1%, extradural abscess in 2.1% and meningitis in 2.1%. The extent of cholesteatoma attic-antrum-mastoid in 25.5%, attic-antrum in 21.3%, attic-tympanum-antrum-mastoid in 14.9% and tympanum-antrum-mastoid in 14.9%. And there were intact stapes in 30 ears (63.8%) and intact stapes footplate in 11 ears (23.4%). Labyrinthine fistula was noted in 5 ears (10.6%), 4 on the horizontal semicircular canal and one on the oval window. The surgical procedure was always procedure was always canal down tympanomastoidectomy except one which underwent atticotomy with tympanoplasty, and tympanoplasty was performed in 80.9% of the ears. Graft failure was experienced in 6 ears (12.8%) and recurrent or residual cholesteatoma was noted in 5 ears (10.6%) during follow-up period. Eight ears (22%) had hearing gain better than 15 dB, and 4 ears (11.5%) worse than 15 dB. postoperatively.