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사례보고 : 간문맥혈전증을 동반한 특발성 문맥고혈압 환자에서 Protein C, Protein S 결핍 1예
황세나 ( Se Na Hwang ),김도영 ( Do Young Kim ),김민주 ( Min Ju Kim ),전영은 ( Young Eun Chon ),이현정 ( Hyun Jung Lee ),박영년 ( Young Nyun Park ),박준용 ( Jun Yong Park ),안상훈 ( Sang Hoon Ahn ),한광협 ( Kwang Hyub Han ),전재윤 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.2
Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal portal hypertension. Among various hepatoportal disorders, noncirrhotic portal hypertension conditions such as idiopathic portal hypertension (IPH) are considered to have a close relation with PVT. PVT is known to have several predisposing conditions, including infection, malignancies, and coagulation disorders. There is growing interest and recognition that deficiencies in proteins C and S are associated with a hypercoagulable state. These deficiencies are regarded as key factors of systemic hypercoagulability and recurrent venous thromboembolism. We report the case of a 19-year-old male diagnosed as IPH with PVT and combined deficiencies in proteins C and S.