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      • KCI등재

        알츠하이머병에서의 시공간 작업기억 특성

        김설민,이영호,윤정혜,이주원,이준영,Kim, Seol-Min,Lee, Young-Ho,Youn, Jung-Hae,Lee, Ju-Won,Lee, Jun-Young 대한생물정신의학회 2009 생물정신의학 Vol.16 No.4

        Objectives : Mild Alzheimer's disease(AD) is uncertain to be related to visuospatial working memory subsystem dysfunction. We used the self ordered pointing test(SOPT) to find the characteristics of visuospatial working memory in mild AD. Methods : We compared the visuospatial working memory abilities of 20 patients with mild AD and 20 normal elderly controls(NC) using SOPT, of which stimuli consisted of two stimuli types(A : abstract, C : concrete) and two stimuli numbers(8 and 12). Therefore, working memory was tested using C8, C12, A8, and A12 stimuli conditions in SOPT. Mixed-model ANOVA was conducted with the AD and NC groups as between-subjects factor, with stimuli types and stimuli numbers as the within-subjects factors and with SOPT error rates as the dependent variable. Results : The AD group showed higher error rates in SOPT than the NC group. The NC group showed low error rates in concrete stimuli than in abstract stimuli and in small stimuli numbers than in large stimuli numbers. And the AD group showed no differences between stimuli types or stimuli numbers. Conclusion : AD patients showed a poor performance in visuospatial working memory using concrete stimuli. The result suggests that there is a non-transformation from visual input to phonological working memory in AD. Patients with AD showed a poor performance although in small stimuli number condition of SOPT. It suggests that in AD, visuospatial working memory is not working well although in low central executive loads.

      • SCOPUSKCI등재
      • SCOPUSKCI등재
      • KCI등재

        경도인지장애 및 알츠하이머병에서의 작업기억 폭 검사 비교

        이수연(Soo Yun Lee),윤정혜(Jung Hae Youn),김주혜(Ju Hye Kim),이준영(Jun-Young Lee) 대한노인정신의학회 2018 노인정신의학 Vol.22 No.1

        Objective:The purposes of this study were to compare the working memory span between mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in the Korean elderly population and to evaluate the effectiveness of the working memory span tests. Methods:32 normal controls (NC), 26 patients with MCI and 28 AD patients at a mild stage were participated in this study. We used newly devised working memory span tests (Word span test and Dot matrix) according to the components of working memory ; central executive, phonological loop, and visuospatial sketchpad. And the results were compared with the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet (CERAD-K). To evaluate the effectiveness of the working memory tests and CERAD-K to screen MCI and AD, receiver operating characteristic curves were plotted. Results:All subsets of the two working memory span tests showed significant decline in verbal and visuospatial working memory in AD. But there was no significant difference between NC and MCI. Compared to CERAD-K, the two working memory tests showed good effectiveness to discriminate AD. Conclusion:This study showed that working memory span tests could be effective diagnosing tools for detecting AD. But for the MCI, the working memory impairment was not prominent than episodic memory impairment. This is supposed to result from the various kinds of working memory components, especially the episodic buffer.

      • KCI등재

        한국 노인용 헤일링(Hayling)검사의 신뢰도 및 타당도

        한경화(Kyung Hwa Han),이준영(Jun Young Lee),이주선(Ju Sun Lee),윤정혜(Jung Hae Youn) 대한노인정신의학회 2020 노인정신의학 Vol.24 No.2

        Objective: The purpose of this study was to verify the validity and reliability of Korean elderly by translating the Hayling Test, a test that measures semantic inhibition ability among executive functions. Methods: Total 91 participants were recruited in accordance with inclusion criteria and exclusion criteria for each group. Within them, 34 were normal from Dongjak-gu, Seoul, 29 were mild cognitive impairment (MCI) from clinics located in Seoul, and 28 were Alzheimer’s disease (AD) from clinics located in Seoul, respectively. The one-way analysis of covariance, the Bonferroni verification, the receiver operating characteristic (ROC) curve analysis, and the Brain Imaging analysis of voxel-based morphometry were conducted in order to compare and analyze performance of demographics characteristics of each group, Hayling Test results, and The Continuous Performance Test-X (CPTX) results. Results: The comparison analysis showed the Hayling Test is more valid methodology than the CPTX test in discriminating normal, MCI, and AD. Furthermore, ROC curves between normal and AD groups also demonstrated higher sensitivity (88%) and specificity (73%) of Hayling Test, and confirmed its diagnostic validity. In line with the above, brain imaging analysis displays significant positive correlation between temporal & frontal brain regions through the Hayling Test scores, however, this correlation was not found for CPTX. Conclusion: It is expected that the Haling Test, which measures language inhibition function, can be used simply and usefully in diagnosing dementia.

      • KCI등재

        남ㆍ녀 중학생의 교복치수 설정을 위한 신체발달 경향에 관한 연구

        李貞順,尹貞惠,趙允珠 복식문화학회 1997 服飾文化硏究 Vol.5 No.3

        The purpose of the study is to analyze the pattern of human developmental growth with empirical anthropometric data for the establishment of the sizing system of junior high school student's uniforms. The sample size was 881 boys and 762 gires between age 12 and 14. An anthropometric database used for this study was the 1992 national anthropometric survey of Korea. The result obtained are as follows ; 1. Several items of anthropometric data on junior high school students showed significant differences in accordance with age and sex. In the meantime, there was no difference on the item of height under the age of 12 between sex, however, significant difference on that age of 11 or over. The hip girth was the biggest growth rate among the item of girth. The somatotype of boys is straight, while girls' shows a curved line. The bodytype of girls shows slim waist, fat belly and hip girth. 2. The result of factor analysis indicated that the first factor was composed with girth, depth and width-measures, and the second factor of height, length-measures. The third factors were consisted of items of representing bodytype of trunk, and the fourth, bodytype of lower part of trunk. 3. The result of cluster analysis indicated that boys were subdivided into 3 types and girls 4 types.

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