유리체강내 포스카넷 주입술을 이용한 거대세포바이러스 망막염치료 2예

윤영채(Young Chae Yoon),최승용(Seung Yong Choi),김민희(Min Hee Kim) 대한검안학회 2020 Annals of optometry and contact lens Vol.19 No.3

Purpose: To report 2 cases of cytomegalovirus (CMV) retinitis treated with intravitreal foscarnet injection. Case summary: (Case 1) A 64-year-old female with acute myeloid leukemia was consulted for ophthalmologic evaluation because of elevated CMV real-time quantitative polymerase chain reaction (RQ-PCR) on her blood. Fundoscopic examination revealed whitish inflitrative lesions at upper-temporal periphery with vitreous opacities on her right eye. We suspected CMV retinitis and performed 4 times of intravitreal ganciclovir injections on her right eye and intravenous ganciclovir injection. After that, whitish infiltrations and vitreous opacities diminished. However, 10 weeks after the initial visit, whitish infiltrations recurred on her both eyes. She already had ganciclovir tolerance and her creatinine clearance also decreased, so that we couldn’t do intravenous foscarnet injection. Alternatively, we did intravitreal foscarnet injection on her both eyes. After the injections, whitish lesions and cytomegalovirs RQ-PCR in anterior chamber was decreased and the visual acuity was increased. (Case 2) A 60-year-old male, who was hospitalized for chemotherapy for diagnoses of diffuse large B cell lymphoma, was consulted for decreased visual acuity of his left eye for 1 month. Fundoscopic examination revealed vitreous opacities and whitish infiltrative lesions around optic disc and uppertemporal periphery of retina on his left eye. We suspected CMV retinitis, and injected intravitreal & intravenous ganciclovir. 2 weeks later, we found another infiltrative lesions at his right eye and also, the CMV RQ-PCR in left eye was increased. So, we decided to do intravitreal foscarnet injections on his both eyes. After the injections, the whitish lesions and CMV RQ-PCR in anterior chamber were decreased. Conclusions: Intravitreal foscarnet injection can be considered in patients with CMV retinitis when it progresses despite of systemic antiviral treatment, when systemic antiviral agents are difficult to use, and when it progresses or recurs after intravitreal ganciclovir injection.

간헐내사시의 임상양상

윤영채(Young Chae Yoon),강남여(Nam Yeo Kang) 대한안과학회 2021 대한안과학회지 Vol.62 No.12

목적: 흔하지 않은 질환인 간헐내사시의 임상특징과 경과, 수술적 치료 결과를 알아보고자 하였다. 대상과 방법: 2007년부터 2020년까지 간헐내사시로 진단받은 9세부터 42세까지의 환자 23명의 의무기록을 후향적으로 분석하였다. 발병 나이, 사시각, 복시 유무, 융합양상, 입체시, 특징적 증상, 그리고 수술 결과를 분석하였다. 결과: 사시 발생 시 평균 연령은 19.9 ± 8세였고 증상 발생 후 평균 23.4 ± 27.1개월에 내원하였으며, 총 13.0 ± 15.6개월 동안 경과 관찰하였다. 초진 시 3명을 제외한 모든 환자에서 주관적 복시를 호소하였고, 78.3%는 간헐적 복시였다. 평균 내사시각은 원거리 21.6 ± 10.3 prism diopters (PD), 근거리 20.2 ± 10.4 PD였다. 2명(8.7%)을 제외한 모든 환자에서 근시를 보였고, 약시는 없었으며 해리상사위는 1명(4.3%)에서 관찰되었다. 워트4등검사상 근, 원거리 모두에서 복시는 5명(21.7%), 억제는 4명이었고 근거리 혹은 원거리에서 융합이 있었던 환자는 14명(60.9%)이었다. 11명(47.8%)에서 수술을 시행 받았는데, 술 후 최종 내원 시 정위 혹은 4 PD 이내의 사시각으로 호전되었고, 복시의 소실 및 융합을 획득하였다. 6명에서 입체시가 개선되었으나 60초각 이하의 정상 입체시 획득은 2명(18.2%)에서만 발생되었다. 결론: 간헐내사시는 주 증상으로 복시를 호소하며, 술 후 정위를 회복하여도 대부분 정상 이하의 입체시로 호전되었고 60초각 이하의 정상 입체시로의 회복은 드물게 발생되었다. Purpose: To evaluate clinical findings and surgical outcomes of intermittent esotropia. Methods: We retrospectively reviewed the medical records of 23 patients (aged 9-42 years) who presented with intermittent esotropia between January 2007 and December 2020. We analyzed the age at onset, angle of deviation, presence of symptomatic diplopia, fusional state, near stereoacuity, and surgical results. Results: The mean age at onset was 19.9 ± 8.0 years and mean duration of esodeviation was 23.4 ± 27.1 months. Mean follow- up time was 13.0 ± 15.6 months. All patients except three had symptomatic diplopia, and 78.3% showed intermittent diplopia. Mean angles of deviation were 21.6 ± 10.3 prism diopters (PD) at distance and 20.2 ± 10.4 PD at near. Twenty-one patients (91.3%) were myopia. No patients had amblyopia and one had dissociated vertical deviation. On Worth’s four-dot test, five patients (21.7%) showed diplopia and four showed suppression at both distance and near. The other patients showed fusion at near or distance. Eleven patients underwent surgical correction. At the final examination, all patients achieved successful motor alignment and fusion with resolution of diplopia. Only two patients (18.2%) achieved normal 60 arcsec stereopsis, and six attained subnormal stereopsis. Conclusions: The main symptom of intermittent esotropia was diplopia. Surgical treatment was effective in achieving good postoperative motor alignment and fusion. However, successful motor alignment did not guarantee recovery of fine stereopsis.

안검 모낭충 감염군과 안구건조증 환자 중 비감염군에서의 마이봄샘 소실 비교

윤영채(Young Chae Yoon),조수연(Soo Yeon Cho),박선경(Sun Kyoung Park),유영식(Young Sik Yoo),황웅주(Woong Joo Whang),나경선(Kyung Sun Na),김은철(Eun Chul Kim),김현승(Hyun Seung Kim),황호식(Ho Sik Hwang) 대한안과학회 2022 대한안과학회지 Vol.63 No.1

목적: 비접촉 마이봄샘촬영술을 이용하여 눈꺼풀 모낭충 감염 여부에 따른 마이봄샘 소실 정도를 비교하고자 하였다. 대상과 방법: 저자들은 눈꺼풀 모낭충에 감염된 24명의 성인 환자와 감염되지 않은 40명의 환자를 대상으로 적외선 디지털 카메라를 사용하여 비접촉 마이봄샘촬영술을 시행하였다. 마이봄샘의 소실을 기준으로 오른쪽 눈의 위눈꺼풀과 아래눈꺼풀의 마이봄점수를 합하여 각 피험자에 대한 전체 마이봄점수를 구했다. 각 그룹의 눈꺼풀 모낭충 감염 여부 및 성별에 따라 마이봄점수를 평가하였다. 결과: 64명 64안이 연구에 등록되었으며, 평균 나이는 67.9세(40-79세, 남자 65.2세, 여자 69.1세)였다. 눈꺼풀 모낭충 감염과 총 마이봄점수, 위 및 아래눈꺼풀 마이봄점수 사이에 유의한 연관성이 있었다(각각, p=0.000, p=0.002, p=0.004). 마이봄점수는 남자와 여자 사이에 유의한 차이가 없었다. 연령과 마이봄점수 사이에 양의 상관 관계가 시사되었으나, 본 연구에서는 집중된 연령 분포로 인해 R2 값이 낮았다. 결론: 비접촉 마이봄샘촬영술을 이용한 검사에서 눈꺼풀 모낭충 감염이 마이봄샘 변화와 유의한 관련이 있었다. Purpose: To compare the degree of meibomian gland drop-out associated with Demodex infestation using non-contact meibography. Methods: We performed noncontact meibography using an infrared digital camera on 24 adult subjects infested by Demodex and 40 without infestation. The right upper and lower lids were scored based on the loss of meibomian glands, and the scores of the upper and lower eyelids were summed to obtain the total meiboscore for each subject. Meiboscores were evaluated according to Demodex infestation and gender in each group. Results: Sixty-four eyes of 64 people were enrolled in this study. The study subjects had an average age of 67.9 years (range, 40-79 years; men, 65.2 years; women, 69.1 years). There was a significant association between Demodex infestation and total meiboscore and upper and lower eyelid meiboscores (p = 0.000, p = 0.002, p = 0.004, respectively). There was no significant difference in the meiboscores between men and women. Age and meiboscore suggested a weak positive correlation; however, the R2 value was low, due to the concentrated age distribution of the study population. Conclusions: Based on noncontact meibography, the authors concluded that the prevalence of changes in the meibomian glands was significantly related to Demodex infestation; however, there was no significant difference between men and women.

經濟成長의 財政政策에 關한 硏究

尹永彩 全北大學校 商科大學 附設 産業開發硏究所 1976 상과대학論文集 Vol.6 No.-

연구대전광역시 쓰레기처리의 정책방향

윤영채 한국환경정책학회 1995 環境政策 Vol.3 No.1

Recently the problem of solid waste disposal has become the most important issue in the world. The solid waste problem can be conceptualized by the gap between the rapidly growing amount of soild waste being generated and the do-crease of solid waste disposal capacity. This paper addresses that the Taejon's solid waste management plan designed in 1992 contains a basic and critical problem which it did not consider the im-pact of quantity-based pricing system on the quantity of solid waste being generated. Above all, therefore, waste stream analysis should be conducted for precise diagnosis and prescription. This analysis offers policy makers information on what sort of and how much solid waste is generated aha disposed after recycling and composting. Data provide that Taejon (46.8%) has produced much higher rate of food waste than Seoul (24.1%). In Taejon, therefore, composting has to be emphasized among waste management options. Importantly, the ser-vice of source-separated food waste collection has to be provided to the public. Furthermore, this paper presents directions of solid waste management policies to deal effectively with the problem of solid waste being generated in Taejon Metropolitan City. To facilitate recycling, drop-off centers can be alternatives to the infrequent co31ectlorl services of recyclables. These recycling facilitate should be established nearby department stores and supermarkets in order to give the convenience of recycling to the public. Finally, this paper suggests that the suc-cessful implernentation of the quantity-based pricing system depend largely on the recycling education and information on what and how to separate materials.

經濟成長의 財政政策에 關한 硏究 : 韓國經濟를 中心으로 한 實證的 硏究

尹永彩 전북대학교 산업경제연구소 1976 전북대학교 산업경제연구소 논문집 Vol.6 No.-

A SUBSTANTIAL ANALYSIS OF FACTORS ASSOCIATED WITH T.V. AD'S SOCIAL RESPONSIBILITY AND IT'S INFLUENCE ON CONSUMER'S BUYING BEHAVIOR.....APPLIED ON AUDIENCE OF JEONJU

Yoon, Young-chae,Hwang, Myung-teak 全北大學校 商科大學 附設 産業開發硏究所 1975 상과대학論文集 Vol.5 No.-

A SUBSTANTIAL ANTIAL OF FACTORS ASSOCIATED WITH T.V. AD'S SOCIAL RESPONSIBILITY AND IT'S INFLUENCE ON CONSUMER'S BUYING BEHAVIOR......... APPLIED ON AUDIENCE OF JEONJU. : Applied on Audience of JEONJU

Yoon, Young-chae,Hwang, Myung-teak 전북대학교 산업경제연구소 1975 전북대학교 산업경제연구소 논문집 Vol.5 No.-