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3차 병원에 입원한 한국 지역사회획득 폐렴 환자에서 미국흉부학회 추천 항생제의 유용성
오성용 ( Sung Yong Oh ),박상준 ( Sang Joon Park ),강경우 ( Kyeong Woo Kang ),고영민 ( Young Min Koh ),서지영 ( Gee Young Suh ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),최동철 ( Dong Chull Choi ),권오정 ( O Jung Kwon ),이 대한결핵 및 호흡기학회 1999 Tuberculosis and Respiratory Diseases Vol.47 No.4
송서영(Seo Young Song),김원석(Won Seog Kim),이혜란(Hye Ran Lee),정현식(Hyun Sik Hyun),이남수(Nam Su Lee),오성용(Sung Yong Oh),김지향(Ji Hyang Kim),김기현(Ki Hyun Kim),남은미(Eun Mi Nam),오영륜(Young Ryun Oh),정철원(Chul Won Jung),윤성수 대한내과학회 2001 대한내과학회지 Vol.61 No.3
N/A Background : To study clinical characteristics and treatment outcomes of adenocarcinoma of unknown primary site (ACUPS). Methods : A retrospective analysis of 81 patients who were diagnosed as ACUPS, seen at Samsung Medical Center from May, 1995 to July, 1999, was performed. Results : The median age of the patients was 58 years. The common sites of metastases were the lymph node, liver, lung, bone. In 49 of 81 patients (60.5%), the dominant tumor location was below the diaphragm. The majority of patiens (76 of 81) were initially treated with systemic chemotherapy including cisplatin. Responses were evaluable in 70 of 76. Eighteen of 70 patients (25.7%) responded to chemotherapy and complete remission was observed in 6 patients. The overall median survival of 81 patients was 5.6 months. The median survival of the responding patients was 18.3 months but the median survial of the nonresponding patients was 4.6 months (p<0.01). In univariate and multivariate analysis, age, performance status and response to initial chemotherapy were significant prognostic factors for overall survial. Conclusion : Poor survival rate and treatment response were observed in ACUPS but complete response and long-term survival were observed in several patients.(Korean J Med 61:234-239, 2001)
김지향 ( Ji-Hyang Kim ),김원석 ( Won Seog Kim ),고영혜 ( Young-Hyeh Ko ),송서영 ( Seo Young Song ),오성용 ( Sung Yong Oh ),김기현 ( Ki Hyun Kim ),남은미 ( Eun Mi Nam ),정현식 ( Hyun Sik Jeong ),윤성수 ( Sung-Soo Yoon ),이홍기 ( Ho 대한내과학회 2001 대한내과학회지 Vol.61 No.4
Background: Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach has recently been defined as a distinct clinicopathologic entity, often associated with Helicobacter pylori (H. pylori) infection. Characteristics and treatment outcomes of 57 patients with gastric MALT lymphoma were analyzed. Methods: Retrospective analysis of 57 cases of gastric MALT lymphoma who underwent treatment with various modalities at Samsung Medical Center from Mar. 1995 to Jul. 2000 was performed. Results: The median age of the patients was 47 years (ranged from 22 to 75 years) and the ratio of males to females was 1.1:1. The presenting symptoms were abdominal pain, indigestion and GI bleeding. By Modified Ann Arbor system, stage 1E accounted for 70.2%, stage 21E 14.0%, stage 22E 14.0%, and stage 4 1.8%, respectively. H. pylori had been evaluated histologically in 49 cases of which 81.6% was positive. Low grade histology accounted for 71.9% and high grade histology 28.1%. Treatment modalities included H. pylori eradication, surgery, chemotherapy, radiotherapy and their combination therapy. In one case, the patient was observed without treatment. Complete remission rate was 98.2%. H. pylori eradication alone resulted in lymphoma regression successfully in 20 out of 23 patients . With median follow-up of 33 months (3-61 months), median survival was not reached. Over all 3-year survival rate was 94.7%. Conclusion: Regardless of treatment modality, high survival rate (3-year survival rate 94.7%) was obtained. H. pylori eradication was feasible and safe in the cases of low grade, stage 1, and H. pylori-positive lymphoma, and allowed stomach preservation. Longer follow-up evaluation is required to determine the long-term efficacy and side effects of H. pylori eradication. (Korean J Med 61:417-423, 2001)