돌발성 난청 완치 직후 수술 및 스트레스로 재발된 임상경험 - 2예 보고 -

여정은(Jung Eun Yeo),송선옥(Sun Ok Song),서동혁(Do 대한통증학회 1997 The Korean Journal of Pain Vol.10 No.1

Sensorineural hearing loss(SNHL) is defined as a sudden hearing impairment which was develope over a period of hours to days. The definitive cause of SNHL is unknown in most cases. Disturbance of the blood flow of the inner ear is a main causal hypotheses. Most symptomatic treatment is focusing to improving the blood flow of the inner ear. At our hospital, most patients are recommended to bed rest, vasodilators(nicotinic acid, antihistamines) and stellate ganglion block(SGB) for two weeks. We experienced two cases of recurrence immediately after recovery from SNHL. They discontinued SGB after initial recovery. due to associated pain with operation and or psychologic stress. One patient resumed SGB and medication treatment, but the second who gave up treatment was not recovered. Therefore, we recommend to continuance of treatment of stellate ganglion blocks to improve recovery rate of SNHL and avoid further trauma and psychologic stress during the recovery period of SNHL.

정맥내 통증 자가조절법을 이용한 말기 암환자의 통증조절

송선옥(Sun Ok Song),여정은(Jung Eun Yeo),김흉대(He 대한통증학회 1996 The Korean Journal of Pain Vol.9 No.1

N/A Background: Nerve blocks, including epidural analgesia, can be risky for terminal cancer pain patients in generally poor conditions. We performed this study to evaluate the effica- cy of intravenous patient-controlled analgesia(PCA) to treat severe pain of terminally ill cancer patients during the last days of life. Methods: We explained the patient's poor general condition to relatives and received a written consent to administer PCA. The starting dose of opioid for PCA in cancer pain management was based on previous 24-hour dose. Previous 24-hour opioid dose was con- verted to intramuscular morphine equivalent. The concentration of opioid mixed into Basal Bolus Infusor® was controlled to allow for one half of the previous 24-hour equianalgesic dose to infuse continuously. Patients controlled their pain by pushing the PCA module themselves. Patients were observed by pain service team. Some discharged patients were treated at home until death. Results: Forty eight patients received PCA for last two years. The most common reason receiving a PCA was the patients poor general condition(52.0%). The mean starting dose of PCA was 20.6±16.2mg of morphine. Over eighty percents of the patients were in good or tolerable state of analgesia. Half of the patients expired within one week. The mean duration of PCA was 8.7±7.0 days. The problems during PCA were: difficulty in maintain- ing intravenous routes, early loss of mentality after starting PCA, hypotension and nausea. Conclusion: We concluded that PCA, if used correctly, is an effective, relatively safe and readily controllable method of pain management in terminally ill cancer patients dur- ing the last days of life. For future considerations, terminal patients may expire at the com- fort of their own homes after the resolution of legal problems regarding using opioid in home care.

Hf<SUB>0.5</SUB>Zr<SUB>0.5</SUB>O₂ 기반의 Ferroelectric Memristor 제작 및 시냅스 특성 평가

박진혁(Jin-Hyeok Pak),송정수(Jeong-Su Song),여정은(Jung-Eun Yeo),이인화(In-Hwa Lee),조한성(Han-Seong Cho),홍진우(Jin-Woo Hong) 대한전자공학회 2023 대한전자공학회 학술대회 Vol.2023 No.11

Due to the limitations of Moores Law, scaling down components in traditional CMOS processing and von Neumann architecture has gradually approached its constraints. Notably, Neuromorphic computing technology, which seeks to emulate the human brain, has gained significant attention. In this study, we have fabricated a two-terminal device which is based on Hf0.5Zr0.5O2 (HZO) thin films and is known as a Ferroelectric Tunnel Junction (FTJ). After device fabrication, we conducted P-V and I-V measurements to assess ferroelectric and memory properties. Then we evaluated the crystalline structure of HZO thin films through XRD analysis. Finally, we successfully implemented Synaptic Functions by applying pulse input.

복강경하 담낭절제술시 전신마취의 방법이 혈압 및 PaCO2 변화에 미치는 영향

송선옥,여정은,김흥대,김홍진 대한마취과학회 1995 Korean Journal of Anesthesiology Vol.28 No.4

Laparoscopic cholecystectomy is a relatively new non-invasive surgical procedures, enjoying ever-increasing popularity and presenting new anesthetic challenges. The advantages of shorter hospital stay and more rapid return to normal activities are combined with less pain associated with the small limited incision and less postoperative ileus. During this procedure, the deliberate pneumoperitoneum with carbon dioxide(CO₂) insufflation may cause some problems such as hypercarbia, hypertension, pneumomediastinum and other cardiovascular impairments. This study was performed to search a anesthetic method, which has least increase in blood pressure during CO₂ insufflation, and to find out whether increased PaCO₂ is a major causative factor in the changes of blood pressure during this period. Sixty patients of ASA class 1 or 2 were classified randomly into 3 groups. Group C(control group) was received enflurane-N₂O-O₂, and others were recieved enflurane-propofol(group P), or enflurane-propofol-fentanyl(group F), respectively. The blood pressure and heart rate were measured at 1 min before CO2 insufflation and 1 min, 5 min, 15 min after insufflation and 1 min before deflation, 5 min after deflation. Also PaCO₂ were checked at 1 min before, and 15 min after insufflation. The results were follows ; 1) Changes of arterial pressure : The control group showed most prominent increasing in systolic and mean blood pressure during CO₂ insufflation(P$lt;0.05). Group F produced the least increase in blood pressure during CO₂ insufflation, compared with group C and P(P$lt;0.05). 2) Changes of heart rate : Although, in the preinsufflation period, heart rates in the group F were significantly lower than other groups, there were no significant changes in heart rates in each group. 3) Changes of PaCO₂: There were no siginificant increases in PaCO₂ in each group, and no differences between the groups. In conclusion, fentanyl and propofol added light enflurane anesthesia could be a method of the least increase in blood pressure during the laparoscopic cholecystectomy, and increased PaCO₂ would not be a major causative factor in hypertension during CO₂ insuftlation.

전신마취시 d-tubocurarine 의 주입속도에 의한 혈역학적 변화

김세연,박대팔,여정은,석제홍 대한마취과학회 1993 Korean Journal of Anesthesiology Vol.26 No.4

d-Tubocurarine(d-TC) causes hypotension, probably as a result of the liberation of histamine; in larger doses, it produces ganglionic blockade. An increase of histamine levels in plasma to 200 to 300 percent of baseline causes a brief decrease in arterial blood pressure(1 to 5 minutes) and the increase in heart rate. The amount of histamine released by d- TC is dose related and is also related to speed of injection. Therefore histamine release can be minimized by the slow administration, light level of surgical anesthesia, and the use of smaller doses. Thus, the purpose of this study was to prevent the cardiovascular effect of d-TC by the slow administration undergoing general anesthesia. The study population was from 40 patients scheduled for elective surgery at Yeungnam University Hospital, who belonged to physical status I or II of ASA classification. Patients were divided into 4 groups by speed of injection of 10, 30, 60 and 120 seconds(group 1, 2, 3 and 4, respectively). All patients were premedicated with hydroxyzine 1mg/kg, glycopyrrolate 0.2mg, and fentanyl 1 ㎍/kg IM 30 minutes before anesthesia. Patients were induced with thiopental sodium 4∼5 mg/kg until the disappearance of lid-reflex. Succinylcholine 1.0 mg/kg IV was used to facilitate endotracheal intubation. As soon as relaxafion was complete, laryngoscopy was initiated. After the completion of intubation, nitrous oxide and 50% oxygen with 0.6% halothane was administrated. The blood pressure and heart rate were measured using noninvasive automatic blood pressure manometer for 60 minutes per 1 minute. Data were analyzed with one-way ANOVA test within the groups. p$lt;0.05 was considered significant. The results were as follows; ·The changes of blood pressure was decreased in rapid injection groups(Group 1 & 2) compared with slowly injection groups(Group 3 & 4) at 2 min, 5 min after d-TC administration. ·The changes of heart rate was significantly increased(p$lt;0.05) at 1min, 2 min after d-TC administration in rapid injection groups compared with slow inection groups. These results show that the cardiovascular effect of d-TC might be prevented by slowly administration undergoing general anesthesia.

동맥관통법을 이용한 액와 상완신경총 차단후 발생한 상완신경총 손상

김종균,송선옥,여정은,지대림 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.35 No.3

A 25-year-old male patient was received emergency operation, open reduction and tenorrhaphy owing to degloving injury on the dorsum of his left hand, under axillary brachial plexus block using a transarterial approach. Following operation, he revealed the signs and symptoms of brachial plexus injury such as weakness, sensory deficit and tingling sensation on his left forearm and hand. The finding on electromyography(EMG), performed on the 16th postoperative day(POD), was indicative of left incomplete brachial plexus injury, mainly in medial cord and ulnar nerve, and partially median and radial nerve at/above the axillary level. The signs and symptoms were improved slightly on POD 8 and a lot on POD 23. The complete recovery of symptoms and regeneration of injured nerve on EMG were confirmed 3 months following operation. In this case, the causative factors of brachial plexus injury were suggested in stretching of the brachial plexus due to improper positioning of injured arm during or after operation, combined with or without injury due to nerve block or tourniquet compression. (Korean J Anesthesiol 1998; 35: 574∼578)