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납-티오황산착물 생성과 구리치환에 의한 수질중 미량 납의 분리 및 분석에 관한 연구
정창웅,엄선섭 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2
A selective and highly sensitive spectrophotometric method has been developed for the determination of trace lead(Ⅱ) with extraction, stripping steps and replacement by copper. The Cu(DDTC)₂complex has maximum absorbance at 435nm and obeys Beer's law in the range of 0.5∼2.5ppm. The molar absorptivity and Sandell's sensitivity are 3.65 x 10⁴L/mol.cm and 10-³㎍/㎠ respectively. The proposed method was applied for the analysis of lead(Ⅱ) in synthetic water.
명평근,엄선섭 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8
Alzheimer's disease(AD) involves a chronic CNS inflammatory response that is associated with both head injury and beta-amyloid pathology. It was reported that the curry spice curcumin reduced oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. Methanol extracts of 18 spices were screened for inhibition of acetylcholinesterase and antioxdative activity in order to evaluate the antidementia activity. The results showed that DPPH radical scavenging activity(IC_50) of Origanus majorana, Salvia officinalis, and Pimenta dioicallis are 161, 179, 71 (㎍/㎖), respectively and the AChE inhibitor activity(% inhibition at 1 mg/㎖) were 53.8, 60.5, 54.6 %, respectively. Bioassay-guided fractionation of Pimenta dioicallis yielded 2-methoxy-4- (2-propenyl)phenol and 2-methoxy-4-(1-propenyl)phenol as antioixdative constituents. It suggest that Pimenta dioicallis(allspice) is a good source of antidementia agent for AD.
명평근,엄선섭 충남대학교 약학대학 의약품개발연구소 2004 藥學論文集 Vol.19 No.-
Alzheimer's disease(AD) involves a chronic CNS inflammatory response that is associated with both head injury and beta-amyloid pathology. It was reported that the curry spice curcumin reduced oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. Methanol extracts of 18 spices were screened for inhibition of acetylcholinesterase and antioxdative activity in order to evaluate the antidementia activity. The results showed that DPPH radical scavenging activity(IC_(50)) of Origanus majorana, Salvia officinalis, and Pimenta dioicallis are 161, 179, 71 (㎍/㎖) respectively and the AChE inhibitor activity(% inhibition at 1 mg/㎖) were 53.8, 60.5, 54.6 %, respectively. Bioassay-guided fractionation of Pimenta dioicallis yielded 2-methoxy-4-(2-pro-penyl)phenol and 2-methoxy-4-(1-propenyl)phenol as antioixdative constituents. It suggest that Pimenta dioicallis(allspice) is a good source of antidementia agent for AD.