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마미총 부위에 발생한 척수관내 말초 신경상피종 : 증례 보고 Case Report
안용봉,이종수,이승재,박효일 대한신경외과학회 1991 Journal of Korean neurosurgical society Vol.20 No.10-11
An unusual case of intraspinal peripheral neuroepithelioma arising from the cauda equina is reported. The patient, a 21-year old female, suffered from low back pain with radiation to the posterior aspect of both legs. Myelographic, computed tomographic scan and magnetic resonance imaging studies of lumbosacral spine showed the intradural extramedullary mass lesion on the L3-S1 level which was excised surgically, but recurred rapidly. It could be diagnosed by the histopathologic findings. The postoperative radiotherapy and chemotherapy were administered. We report this rare case with review of the literatures.
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요추간판 탈출증 환자에서 화학적 수핵 융해술 및 자동 경피 수핵 제거술의 비교 분석과 임상적 고찰
구영환,김형기,안용봉,이상걸,박문선,김병준 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.6
The authors reviewed the radiographs and medical records of 134 consecutive patients who underwent chemonucleolysis and automated percutaneous lumbar discectomy(APLD) between March 1990 and December 1994 at our institute. Among the 134 consecutive patients, 90 patients underwent chemonucleolysis and the other remaining patients underwent APLD using a nucleotome. The results are summarized as follows : 1) In both groups, predomient patients were of young age and males. 2) The most common lesion was in L4-5 interspace inn both groups. 3) The posterior lateral type showed high incidence in APLD group. 4) The results were better in the younger age group and when spinal CT demonstrated posterior lateral type in both groups. 5) The results showed relatively good success rate of 84.4% in chemonucleolysis group and 88.6% in APLD group. 6) Better results can be anticipated when patients are carefully selected and operated on with a higher skillful technique.
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Circulating Antigen and Antibody Responses in Acute Toxoplasma Infection of Rabbits
Lee, Young-Ha,Jin, Eun-hee,Ahn, Yong-Boong,Oh, Chang-Jin,Shin, Dae-Whan 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2
톡소포자충(Toxoplasma gondii) 감염의 진단은 면역혈청학적 방법에 의한 항체 측정이 주로 이용되고 있으나 감염 초기(급성기) 및 면역적 장애를 가지고 있을 경우에는 이러한 방법으로 진단하기 어렵다. 이에 저자는 급성 톡소포자층 감염의 진단법으로 많이 이용되고 있는 항체 측정법을 순환 항원 검출법과 비교 평가하여 그 상관관계를 조사하였으며, 또한 혈청내 항원의 출현 양상을 조사하였다. 가토에 톡소포자충 RH주의 tachyzoites를 가토당 1,000개씩 피하 주입한 다음 2일 간격으로 20일 동안 채혈한 후 혈액내 충제, 순환 항원, IgM, 및 IgG항체변화와 immunoblot에 의한 항원의 출현을 조사하기 위하여 동물접종검색, ELISA, 및 Western blot을 실시하였다. 가토 혈액 0.5cc를 마우스 복강에 주입 후 3주 동안 관찰한 결과 감염 후 2일부터 감염 10일 사이에 채취한 혈액을 투여한 마우스에서 톡소포자충이 분리되었다. 톡소포자충에 대한 순환 항원은 감염 후 2일부터 검출되기 시작하여 감염 12-14일에 가장 높은 흡광도를 나타냈으며, 그 후 감소하였다. 혈청내 톡소소포자충에 대한 IgM 항체가는 감염8일부터 유의하게 증가하여, 감염 14-16일에 최고치를 보였으며, 혈청내 IgG항체가는 감염 10일부터 유의하게 증가하여 그후 계속적으로 증가하였다. 혈청내 순환 항원은 IgG 항체가보다 IgM항체가의 변화와 높은 연관성을 보였다. 또한 톡소포자충 감염 가토 혈청은 감염 기간에 따라 특징적인 공통 항원 band를 볼 수 있었다. 이상의 성적으로 보아 톡소포자충 감염 가토의 혈청내 순환 항원은 IgM 항체가 및 혈청내 충체내 검출 성적과 높은 상관 관계가 보여 급성 톡소포자충증의 진단 및 확인에 있어 유용할 것으로 사료된다. Toxoplasma gondii is a protozoan that is parasitic in humans and other animals. T. gondii infection is usually diagnosed by significant increases in specific IgG and IgM antibodies. These tests are not reliable in immunodepressed patients, nor are these possible to differentiate clearly between the acute and latent forms of toxoplasmasis. The detection of Toxoplasma antigen has been proposed as a valid alternative for, the diagnosis of this parasitic infection. To assess the correlation between circulating Toxoplastna antigen and antibody response, 1,000 tachyzoites of T. gondii per rabbit were subcutaneously injected into rabbits. The parasitemia, circulating antigen, IgM and IgG antibody titers and IgG antibody binding bands were serially checked in the blood from infected rabbits by mouse inoculation method, ELISA and Western blot. Mice received blood of rabbits infected with T. gondii were dead from day 2 post infection (PI) to day 10 PI. Circulating antigens were first detected from 2 days after infection, and their titers were markedly increased from day 4 and peaked on day 12 PI. The IgM antibodies were not significantly increased until day 6 PI, and peaked on day 14-16 P1. IgG antibodies were detected from day 10 P1, thereafter their titers were continuously increased during experiment. The titers of circulating antigens were closely correlated with IgM antibody titers than IgG antibody titers. The IgG antibody binding bands were specific according to infection period. From these results, rabbits infected with RH strain of T. gondii revealed that circulating antigens are closely correlated with IgM antibody than IgG titers as well as related with parasitemia, therefore this study proved the value of detection of circulating antigens in the diagnosis of acute toxoplasmosis.
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조규찬,정호,안용봉,이상걸,이영근 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.6
A retrospective analysis of 33 cases with operated delayed intracrainal lesion who were admitted to EUl Ji General Hospital from January 1990 to December 1992 was made according to their age and sex, etiology, lesion site, time interval to finding delayed intracrainal lesion, brain CT findings, relationship of GCS in initial and delayed lesion, associated injuries, treatment and prognosis(GOS). The results were as follows : 1) The young males on first to second decade were most frequently affected. 2) The most common cause was pedestrian accident by motor vehicle, followed by fall down. 3) The most common associated injury was skull fracture, followed by skeletal injury of extremity. 4) The most common delayed intracranial lesion was delayed epidural hematoma on youth. 5) The most frequent time interval when the delayed intracranial lesion may be occurred was from 12hr to 24hr after admission. 6) The most possible intial lesion which the delayed epidural hematoma may be occurred was scanty hematoma with pnumocephalus or CSF leakage. 7) The GOS(Glasgow Outcome Scale) of analysed 33 cases were good in 60% and poor in 40%, i.e good recovery(42%), moderate disability(18%), severe disability(15%), vegetative state(12%), death(12%).
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경추강내 지주막 낭종 1례 : 증례보고 Case Report
김형기,신영귀,정호,안용봉,이상걸,박문선 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.10
The authors have experienced a case of an arachnoid cyst within the cervical. The patient suffered from right upper extremity pain and numbness for 1 monty. On cervical MRI intradural extramedullary mass was detected. A total laminectomy of C5. C6 and C7 was performed. We could diagnose by radiological and pathological findings.
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