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쥐의 뇨 중에서 Pyrovalerone 의 새로운 대사체들의 여러 가지 유도체화를 통한 구조해석
신호상,박종세 ( Hosang Shin,Jongsei Park ) 생화학분자생물학회 1994 BMB Reports Vol.27 No.5
Identification of the new metabolites of pyrovalerone was described. Three new metabolites of pyrovalerone in rat urine were identified by gas chromatography-mass spectrometry (GC-MS). The structural elucidation of the metabalites was carried out by interpretation of the mass spectra of their various derivatives. Almost all of the metabolites were extracted in the acidic urine after enzyme hydrolysis and these metabolites had the carboxyl group. A metabolite was extracted as a unconjugated basic compound in the urine. The metabolites can be screened by the described extraction method.