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      • KCI등재

        외부정도관리(外部精度管理)에 의(依)한 내부정도관리(內部精度管理)의 분석연구(分析硏究) -Na, K, Cl 및 Ca를 중심(中心)으로-

        이국성 ( Kook Sung Lee ),박은병 ( Eun Byoung Park ),이창규 ( Chang Kyou Lee ) 대한임상검사과학회 1984 대한임상검사과학회지(KJCLS) Vol.16 No.1

        The clinical laboratory quality control has been almost daily routinized ever since the first notion brought from the industrial merchant quality surveillance. The progress has been mainly attributed by remarkable development of sophisticated instrument, ever changing methodologies and refined reagents. Despite the progress, the status of the quality control program is some what differ from one subject to another even in a same laboratory. In a way, it is not deniable that much emphasis has been centered on the external quality control program rather than on the internal quality control program development which should actually be considered prior to the external quality control program. The study was attempted, therefore, on a well-initiated internal quality control status analysis of biochemistries at the A hospital laboratory, a participating member of the Korean Society of Quality Control in Clinical Laboratory. The analysis and the evaluation were made on some routine chemistry tests, such as Na, K, CI and Ca. The data obtained from the laboratory were projected to the date of the KSQCCL which initiated an external quality control surveillance from June, 1980 to June, 1982. 1. The constant error of the Na determination was judged as negligible while the negative proportional error was shown relatively serious, and the precision of it was also interpreted as a little unsatisfactory. 2. Both the accuracy and the precision of K determination of the internal quality control status were evaluated as satisfactory. 3. As far as CI determination is concerned, the proportinal error in its accuracy was found to be more serious than the constant error, and the precision of it was also interpreted as a little unsatisfactory. 4. Both the accuracy and the precision of Ca determination in the internal quality control status were evaluated as unsatisfactory.

      • ISE에 의한 血淸 Na, K의 測定硏究

        崔命宰,朴銀秉,李昌珪 高麗大學校 倂設 保健大學 保健科學硏究所 1985 保健科學論集 Vol.14 No.1

        We have evaluated the performance of sodium and potassium measurement using the Corning 902 direct potentiometric ISE. The comparative method in this study was the Corning 480 flame photometry. The comparison of two methods are here by summarized as below: 1. A total of 25 patient serum samples were chosen at random basis from routine submissions. Analysis of serum samples on the Corning 480 yielded results of 151.96±l.44mEq/L for Na and 7.21±0.08mEq/L for K, while the results by the Coming 902 were 149.73±1.08mEq/L for Na and 7. 26±0.10mEq/L for K. No significant difference observed for the mean values between two methods. 2. Analysis of 30 consecutive day specimens with abnormal control serum on the Corning 480 yielded results of 151.96±l. 44mEq/L for Na and 7.21±0.08mEq/L for K, while the Corning 902 yielded results of 149.73±l. 08mEq/L for Na and 7.26±0.10mEq/L for K. Significant difference was observed for the mean values obtained from Corning 902 when compared to Corning 480. The Corning 902 result for Na in serum is about 1.5% less than the Corning 480 result; for K this difference is about +0.7%. 3. In between-day precision studies, the CV of the Corning 480 was 0.95% for Na and 1.19% for K respectively, while Corning 902 was 0.72% for Na and 1.41% for K. 4. Analysis of 25 patient sera on Corning 902 compared to Corning 480 gave a correlation coefficient of 0.959, with a slope 0.926 and intercept equal to 10.81 on the Na results; correlation coeffi-cient of 0.968, with a slope of 0.999 and intercept equal to -0.15 for K. 5. It can be concluded that the Coming 902 offers excellent alternative for the routine analysis of sodium and potassium particularly in its stability, safety, rapidity, ease of operation, and reliable analytical performance.

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