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박으뜸,박유헌,박성선,서형주,Park, Eu Deum,Park, Yooheon,Park, Sung-Sun,Suh, Hyung-Joo 한국식품영양학회 2012 韓國食品營養學會誌 Vol.25 No.4
본 연구에서는 혈액 내에서의 오메가-3 지방산의 함량 변화를 측정하여 연질 캡슐과 장용성 캡슐의 차이를 검토하였다. Fish oil 중의 EPA와 DHA의 총합의 함량이 62.87 g/100 g으로 대부분을 차지하고 있다. 연질 캡슐의 경우, 제 1시험액(위액)에서는 내부의 지방이 70% 용출된 반면, 장용성의 경우 10% 정도만이 용출되었다. 제 2액(소장액)에서도 6시간까지 50% 정도 용출되어 90분에 50%가 용출된 일반 연질 캡슐과 대조적이었다. 기존에 사용하였던 연질 캡슐의 EPA 및 DHA는 흡수 초기에 장용성 캡슐에 비하여 다소 높은 비율을 보인 반면, 8시간 이후 장용성 캡슐 섭취한 경우 EPA와 DHA의 혈액내 함량이 비율이 증가하는 경향을 보였다. 경구 투여 48시간 후 지방산 조성은 장용성 캡슐에서는 mono-, poly-unsaturated fatty acid 혈액 내의 함량이 다소 높은 경향을 보였으며, saturated fatty acid 함량 역시 다소 높은 경향을 보였다. EPA와 DHA의 함량은 혈액 내에서 각 지방 분획에서의 함량 차이를 정확하게 측정하기 힘들었다. 이상의 결과에 의하면 장용성 캡슐은 위장관을 통과하여 장에서 용출되는 특성 때문에 지속적인 효과를 기대할 수 있을 것으로 추정된다. We investigate the changes of fatty acids in blood for an evaluation of the effects of soft and enteric coated capsules containing omega 3 fatty acids. Fish oil, which contained 62.87 g/100 g of sum of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), was used as nutracueticals for omega 3 fatty acids. Lipid releasing amount in soft capsule was 70% in stomach condition. However, there was 10% of releasing amount of lipid observed in enteric coated capsule in stomach condition. In intestinal condition, 50% of lipid releasing amount in enteric coated capsule showed until 6 hr, but soft capsule until 90 min. EPA and DHA contents in soft capsule administration showed higher level than those in enteric coated capsule until 8 hr. However, the administration of enteric coated capsule showed higher level of EPA and DHA in blood after 8 hr. After 24 hr, mono-, poly-unsaturated and saturated fatty acids contents with enteric coated capsule showed higher level than those with soft capsule. The enteric coated capsule containing omega 3 fatty acids was expected to sustain omega 3 fatty acids.
박으뜸,이병언,강동식,김정,강범수,송우진 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.4
A flow stress model is developed prior to a material formability evaluation using analytical analysis. However, some existing models do not consider the effects of temperature on the flow stress, while others utilize a complicated process to predict the temperaturedependent behavior. Previously, the modified Hollomon and modified Ludwik models were proposed as flow stress models that incorporate the effects of temperature, but that involve relatively simple processes. However, in those models, the material constants are formulated as temperature-dependent linear equations only. In this study, material constant equations (the yield stress, strength coefficient, and work hardening exponent) based on the modified Ludwik model are obtained for a laminated sheet composed of an aluminum alloy and self-reinforced polypropylene (SRPP); these expressions are then examined in detail using nonlinear regression analysis. Newly modified models are created, in which the material constants are modeled using combinations of quadratic and exponential temperature-dependent equations. Then, the previous and newly modified models are evaluated by comparing their average maximum absolute errors and R-squared errors against experimental data. Hence, the best-fitted flow stress models are determined. Models comprising a combination of quadratic equations, or a combination of exponential (yield stress) and quadratic equations, yield the greatest accuracy.
섬유금속적층판 제작을 위한 PTFE 몰드 기반 마이크로파 공정에 대한 실험적 연구
박으뜸,이영헌,김정,강범수,송우진 한국소성∙가공학회 2020 소성가공 : 한국소성가공학회지 Vol.29 No.4
Existing composite forming processes such as the autoclave, prepreg compression forming (PCF), RTM, etc. require high production costs because of their long processing time. On the other hand, microwave heating process (MHP) can reduce the production costs since both mold and composite material can be heated directly. The aim of this study is to manufacture a mold consisting of polytetrafluoroethylene (PTFE), quartz glass, stainless steel clamps, and polyether ether ketone (PEEK) bolts for fabricating FML based on self-reinforced polypropylene (SRPP) using the MHP. First, the flame test was carried out prior to the MHP to check the temperature on the mold and whether the spark occurred at the mold and the edge of the FML. Second, the uniaxial tensile test was then conducted to obtain the mechanical properties of the FML manufactured by the MHP. The mechanical properties were compared with those of the FML fabricated by the PCF. As a result, the MHP using the PTFE mold can manufacture the FML more rapidly than the PCF, and obtain acceptable mechanical properties.
Resveratrol Inhibits Lipopolysaccharide-induced Phagocytotic Activity in BV2 cells
박으뜸,김도경,전홍성 한국응용생명화학회 2012 Applied Biological Chemistry (Appl Biol Chem) Vol.55 No.6
The inhibitory effects of resveratrol, a natural bioactive polyphenolic phytoalexin rich in grape, on lipopolysaccharide (LPS)-induced microglial activation and its beneficial effects on dopaminergic neurodegeneration were studied. Resveratrol dosedependently suppressed LPS-induced nitric oxide production and the expression of inducible NO synthase (iNOS) in BV-2 microglial cells. Furthermore, resveratrol (1 μM) significantly blocked BV2microglial phagocytosis induced by LPS (0.1 μg/mL). Although the conditioned media from LPS-stimulated BV2 cells caused the SN4741 dopaminergic neuronal cell death, that from resveratrolpretreated BV2 cells did not diminish the viability of SN4741cells. These results suggest that resveratrol can prevent neuronal death possibly through the modulation of phagocytosis and microglial activation.
박으뜸(Euddeum Park),양인영(Inyoung Yang) 한국자동차공학회 2010 한국자동차공학회 부문종합 학술대회 Vol.2010 No.5
CFRP (Carbon Fiber Reinforced Plastic) is coming to be used from various field. Gradually the valence of accident according to increasing, the safety of mobile means being demanded more, is going. In order to raise safety the material which is the possibility to raise a shocking absorption more necessary. This paper is writing experiment result with character in gives the condition which specifies CFRP (Carbon Fiber Reinforced Plastic) that is one among those materials. This paper focus on comparison of water absorption rate and analysis of the change of energy absorption, which is under dry or wet condition, according the interface numbers of circular CFRP specimen which is under the hygrothermal environment.
열습환경하에서 계면수에 따른 CFRP 튜브의 흡수에너지특성
박으뜸(Eu-ddeum Park),양인영(In-young Yang) 한국자동차공학회 2009 한국자동차공학회 지부 학술대회 논문집 Vol.2009 No.10
CFRP (Carbon Fiber Reinforced Plastic) is coming to be used from various field. According to characteristic of high elasticity and light weight use the sporting goods and the vehicle bonnet, aerospace craft etc. For a safety shock the research which absorbs is extending plentifully, At the time of does a safety and a lightweight anger first of all under demand conditions as the shocking absorption energy. Insect family hour height as the material CFRP is being paid attention a demand condition. But, CFRP efficiencies fall by moisture. This paper focus on comparison of water absorption rate and analysis of the change of energy absorption, which is under dry or wet condition, according the laminate numbers of circular CFRP specimen which is under the hygrothermal circumstance. Compares in the specimen which constructs conclusively the energy absorption quantity of the specimen which gets wet is lowly measured 10% degree.
자동차 측면 도어의 섬유금속적층판을 적용한 임펙트 빔의 수치해석에 의한 성능 평가
박으뜸 ( Eu-tteum Park ),김정 ( Jeong Kim ),강범수 ( Beom-soo Kang ),송우진 ( Woo-jin Song ) 한국복합재료학회 2017 Composites research Vol.30 No.2
섬유금속적층판은 금속 판재와 섬유 강화 플라스틱을 적층한 하이브리드 소재 중 하나다. 섬유금속적층판은 부품 경량화 측면을 고려했을 시, 뛰어난 충격흡수능력을 가지고 있기 때문에 자동차 및 항공우주 산업에서 적용 및 연구를 진행하고 있는 추세다. 특히, 자동차의 측면 도어 임펙트 빔의 경우, 기존의 금속소재에서 복합재료로 대체하기 위한 연구가 활발히 진행 중이다. 본 연구에서는 자동차의 측면 도어 임펙트 빔을 금속소재와 자기 강화형 폴리프로필렌을 적층한 섬유금속적층판으로 대체하는 것이 목표다. 3가지 종류의 임펙트 빔의 3점 굽힘 시험 수치해석을 통해 단면적 대비 굽힘 저항력의 크기를 비교하였다. 그 후, 제작 실현성을 고려하여 굽힘 저항력이 우수한 이중모자형 임펙트 빔을 순수 DP 980과 섬유금속적층판으로 제작하여 자동차 측면 도어에 설치된 모델을 상정하고 충돌 해석을 수행하였다. 결과적으로 섬유금속적층판을 사용한 임펙트 빔은 기존의 DP 980보다 무게 대비 충격 에너지 흡수 능력이 약 7배 높음을 알 수 있었다. The fiber metal laminate is a type of hybrid materials laminated thin metallic sheets with fiber reinforced plastic sheets. The laminate has been researched or applied in automotive and aerospace industries due to their outstanding impact absorbing performance in view of light weight aspect. Specially, the replacement of side-impact beam as the fiber reinforced plastic has been researched actively. The objective of this paper is the primitive investigation in the development of side-door impact beam using the fiber metal laminate. First, the three-point bending simulations were conducted to decide the shape of impact beam using the numerical analysis. Next, two cases impact beam (pure DP 980 and fiber metal laminate) were installed in the side-door, and then the bending tests (according to FMVSS 214S) were simulated using the numerical analysis. It is noted that the side-door impact beam can be replaced with the fiber metal laminate sufficiently based on the numerical analysis results.