톨루엔 취급 근로자의 건강장해

문영한,노재훈,Moon, Young-Hahn,Roh, Jae-Hoon 대한예방의학회 1986 예방의학회지 Vol.19 No.2

Subjective symptoms, counts of blood cells and liver function test were conducted on 198 male workers who were exposed to toluene in Kyungin area from September to November, 1986. According to the level of urinary hippuric acid concentration, the total sample was classified into the high exposure group ($concentration{\geqq}3g/1$) and the low exposure group(concentration<3g/1). The following findings were obtained by comparing the two group: 1) Contrary to the previous findings. the urinary hippuric acid concentration of toluene exposed workers showed bimodal distribution. It meant that the toluene exposed workers were mixed with the non-exposed or minimal exposed workers. 2) The high exposure group showed a lower level of leucocytes counts ($6,630{\pm}1,860{\mu}l$) than the low exposure group ($6,340{\pm}1,960/{\mu}l$). 3) The high exposure group showed a higher level of SGOT, SGPT and r-GTP than the low exposure group (p<0.05). 4) The high exposure group complained much more subjective symptoms (e. g. skin rash, loss of appetite, palpitation) than the low exposure group.

유기용제 취급의 자각증상호소에 대한 연구

천용희,문영한,Cheon, Yong-Hee,Moon, Young-Hahn 대한예방의학회 1984 Journal of Preventive Medicine and Public Health Vol.17 No.1

The subjective symptom and other responded relations for 69 male workers handling organic solvent in xxx a pharmacy as exposure group and 87 male workers in noise workshop were studied and analyzied. It was concluded as follows. 1. The age of both exposure group and control group with the subjective symptom indicated a negative correlation. 2. Drinking and smoking of the exposure group complained of the subjective symptom shown the negative correlation and the control group also shown the positive correlation. 3. The occupational experience of the exposure group complained of the subjective symptom indicated the negative correlation and the control group also indicated the positive correlation.

자각증상 평가를 위한 예측치공식의 이용성에 대한 연구 -모 공장 유기용제 취급자를 중심으로-

천용희,문영한,오대규,Cheon, Yong-Hee,Moon, Young-Hahn,Oh, Dae-Kyu 대한예방의학회 1983 Journal of Preventive Medicine and Public Health Vol.16 No.1

For the study of the applicability of predictive equation of subjective symptoms of workers using organic solvents, 67 male workers using organic solvents were selected. The predictive equation was quotated from previous Cheon's study. All the datas of necessary variables were gained. The predictive values and observed values were compared. The results were summarized as below; 1. The difference between predictive values and observed values were characteristically large. The coefficient of determination between the two values was 0.0024. 2. The $R^2$ value of multiple stepwise regression equation derived from present study was 0.2827.

진동공구 사용근로자의 피부온도 변화

노재훈,문영한,신동천,차봉석,조수남,Roh, Jae-Hoon,Moon, Young-Hahn,Shin, Dong-Chun,Cha, Bong-uk,Cho, Soo-Nam 대한예방의학회 1988 Journal of Preventive Medicine and Public Health Vol.21 No.2

충청북도 단양지역 착암 근로자 79명과 착암기를 사용하지 않는 광산 근로자 39명을 대상으로 1987년 6월 10일부터 1987년 6월 19일까지 면접 조사 및 집단 검사를 시행하여 다음과 같은 결과를 얻었다. 1. 창백지(white finger)는 오른쪽 손에 더 많이 나타났다. 2. 창백지 발현에 진동 노출량, 연령, 음주 및 흡연 여부가 통계학적으로 유의한 변수로 선정되었다. 3. 진동 증후군 증상자의 수지부 통각역치가 대조군에 비해 증가되었다. 4. 냉수 침적후 진동 증후군의 피부온도가 대조군에 비해 낮았으며 회복은 대조군에 비해 지연되는 경향을 보였다. By implementing epoch-making policies for industrial promotion, the national economy has made a remarkable development. As a result of such economic growth, industrial accidents and occupational diseases have become a serious problem in Korean society. In the presidential order for the execution of the Korean Labor Standard Law, neuritis and other diseases stemming from health impairments due to vibrations in industrial processes are designated to be dealt with as vibration diseases. In the case of vibration disease, industrial accident compensation is not effectively paid. In order to investigate the vibration hazards of rock-drill operation, the authors studied the subjective symptoms and performed physical function tests on a total of 79 persons (vibration exposed group) who used rock-drills, and 39 persons (control group) who did not use rock-drills at anthracite mines. The results of the physical function test were as follosws : 1. The right hand was more affected by white finger than the left hand. 2. Independent variables such as duration of rock-drill operation, age, drinking and smoking were indentified as statistically significant factors for the occurrence of white finger. 3. In the pain sense threshold, the group with Raynaud's phenomenon showed a statistically higher level than that of the control group. 4. The skin temperature of the group with Raynaud's phenomenon was lower than that of the control group. The recovery time of skin temperature aftr cooling was delayed compared with the value of the control group.

염료공장 근로자의 직업성 천식에 관한 역학적 연구

이경종,문영한,노재훈,박해심,홍천수,Lee, Kyung-Jong,Moon, Young-Hahn,Roh, Jae-Hoon,Park, Hae-Sim,Hong, Chein-Soo 대한예방의학회 1990 예방의학회지 Vol.23 No.3

This study investigated the symptoms, medical and occupational history of 424 workers of 5 reactive dye Industries in the Inchon area in Korea. The study was performed on March 6 and July 19, 1989. The tests applied to the subjects were : serum total IgE, specific IgE, skin prick test with 7 inhalatory antigens, pulmonary function test, chest X-ray, methacholine test, and bronchoprovocation test. The workers were classified according to these tests into 4 groups (healthy, realtively healthy, need careful medical observation, and occupational asthma), and were compared in terms of the group characteristics and the symptom prevalence. The prevalece of occupational asthma of workers in reactive dye was 5.9% Significant differences were observed among the 4 groups. The groups were significantly different in the variables of sex and duration of smoking among their general characteristics ; and dyspnea, wheezing, chest pain, cough, nasal symptoms and sore throat among symptoms ; asthma, bronchitis, and other respiratory diseases with respect to their past medical history. This study suggests that we should pay special attention to the workers exposed to the risk of occupational asthma.

서울시 대기중 유기오염물질의 농도와 돌연변이원성에 대한 연구

신동천,정용,문영한,노재훈,Shin, Dong-Chun,Chung, Yong,Moon, Young-Hahn,Roh, Jae-Hoon 대한예방의학회 1990 Journal of Preventive Medicine and Public Health Vol.23 No.1

To evaluate the difference of concentration and mutagenicity of organic pollutants between residential and traffic area of Seoul, air samples were collected in Bulkwang (residential) and Shinchon (traffic) area. Samples were analyzed to measure the concentration of extractable organic matters (EOM) and their subfractions and mutagenicities were tested using Salmonella typhimurium TA 98. The concentrations of polycyclic aromatic hydrocarbons (PAHs) were also measured by gas-chromatography and compared between two areas. The results were as follows ; 1. While the concentration of total suspended particulate (TSP) in residential area was below the environmental standard in annual average, the concentration in traffic area was above the standard and was up to its maximum $256{\mu}g/m^3$ in November. The difference of TSP concentrations in both areas of each month was statistically significant (P<0.05). 2. The concentration of fine particle in traffic area was significantly higher compare to that in residential area and showed statistically significant monthly difference in both areas (P<0.05). The proportion of concentration of fine particle to TSP was 55-68%. 3. Mean concentrations of EOM in residential and traffic areas were $4.3{\mu}g/m^3\;and\;5.3{\mu}g/m^3$ respectively. The proportion of amount of EOM from fine particle to EOM from TSP was 70-88%. 4. While the percentage of polar neutral organic compounds (POCN) of fine particle in Bulkwang's sample was higher compare to Shinchon's sample, the percentage of aliphatic compounds of fine particle in Shinchon's sample was higher compare to Bulkwang's sample. The percentages of PAH fraction were as low as 6-10% in both areas. 5. The mutagenic activity of nit concentration of organic matters extracted from fine particle was higher compare to that of coarse particle and was increased when metabolically activated with S9. Mutagenicities with metabolic activation calculated by unit air volume were significantly different between residential and traffic area, $17\;revertants/m^3$\;and\;22\;revertants/m^3$ respectively. 6. The concentrations of benzo(a)pyrene in fine particle of traffic and residential areas were $3.10ng/m^3\;and\;2.02ng/m^3$ respectively. Sixteen PAHs were higher in samples of traffic area compare to residential area and also concentrations of PAHs in fine particle were higher compare to coarse particle.

진폐환자 입원치료시 노력성 폐활량 및 1초 폐활량의 변화에 대한 연구

천용희,정호근,문영한,정호용,Cheon, Yong-Hee,Chung, Ho-Keun,Moon, Young-Hahn,Chung, Ho-Young 대한예방의학회 1986 Journal of Preventive Medicine and Public Health Vol.19 No.2

Forced vital capacities (FVC's) and forced expiratory volumes in one second $(FEV_{1.0}'s)$ of 26 pneumoconiosis patients were checked at admission and were followed up for 10 months through hospitalization. FVC's and $FEV_{1.0}'s$ were slightly improved in 10 months after admission. The improvement of FVC's was statistically significant. In the group of large opacities in chest radiographs, FVC's and $FEV_{1.0}'s$ were lower than those values in small opacity group at admission but improved more progressively. Similar finding was noted in the group of emphysema; those values were lower at admission but improved more progressively than those of non-emphysema group.

도로 교통 소음에 대한 교사와 학생들의 반응

김증호,이경종,문영한,노재훈,윤명조,Kim, Ceung-Ho,Lee, Kyung-Jong,Moon, Young-Hahn,Roh, Jae-Hoon,Yoon, Myung-Cho 대한예방의학회 1995 예방의학회지 Vol.28 No.4

The purpose of this study is to reveal how the road traffic noise influences on the response of teachers and students, which composed of conversation, studying, relaxation, and physical disturbances. The research method used in this study was self-administrated questionnaire. Samples of the survey were composed of 420 persons(114 teachers and 306 students) who are exposed to traffic noise less than 65 dB(A) from two junior high schools and 410 persons(140 teachers and 270 students) from two noisy junior high schools which the road traffic noise above 65 dB(A). In the response of both of the teachers and students in noisy(above 65 dB) schools complaints of disturbances of conversation, studying, relaxation, and physical disturbances are much higher than that of less noisy schools' teachers and students(p<0.01). On the occasion of time and season, the subjects answered the traffic noise cause high troublesome and stresses in the afternoon(12:00 - 17:00) and summer respectively. It is necessary to provide governmental comprehensive and fundamental measures to improve the noisy school environments.

n-Hexane 및 Benzene이 백서 경골신경에 미치는 영향

이영수,노재훈,문영한,Lee, Young-Soo,Roh, Jae-Hoon,Moon, Young-Hahn 대한예방의학회 1987 Journal of Preventive Medicine and Public Health Vol.20 No.2

n-Hexane and benzene are organic compounds which have been widely used as industrial solvents. However, they are also increasingly recognized as important pollutants in working environment. The purpose of this study is tp analyze neurotoxicity of benzene and n-hexane. In this study, tibial nerve of Sprague-Dawley rats were observed after exposing them to two different concentrations of these compounds (6000 ppm of n-hexane and 2000 ppm of benzene) which were known to be the levels to cause subacute toxicity for the three different periods; two weeks, four weeks, and six weeks. The following results were obtained from the analysis of variance, Duncan's multiple comparison test, and regression analysis: 1) Myelin sheath thickness of nerve fiber for two n-hexane exposed groups (four weeks and six weeks) were both reduced compared with the control group and the benzene exposed group. 2) There were positive relationships between nerve fiber diameter and myelin sheath thickness for both exposed and control groups. 3) There was no significant difference in myelin sheath thickness from equal diameter nerve fibers between benzene exposed group and control group, but the greater number of thin myelin sheath were observed for n-hexane exposed group compared with control group. Thus, it is concluded that n-hexane tends to reduce the rate of growth of nerve fiber more than the benzene and control group. While these results shed light on understanding the effects of benzene and n-hexane, the duration of exposure was not long enough to apply these results to real working environments. In addition, to further understand the mechanims of nerve degeneration caused by organic solvents, both epidemiological and biochemical studies should accompanied by this kind of study.

인자분석을 통한 유기용제 취급자의 자각증상 호소에 관여하는 변수에 관한 연구

천용희,정호근,문영한,Cheon, Young-Hee,Chung, Ho-Gun,Moon, Young-Hahn 대한예방의학회 1985 Journal of Preventive Medicine and Public Health Vol.18 No.1

By using Factor analysis on the variables relating to the subjective symptoms of total 56 workers, who have exposed to mixture of organic solvents at the musical instrument manufacturing plant, as experinmental group, and 70 workers, who worked in noisy working environment as control group, the study was performed. It was confirmed that the variables found in hematological figures, age specification, occupational history and physical examination have a influential factor on the subjective symptoms of both groups. It was explicated that the ratio of these to total Eigen Values showed 31.1 percent in experimental group and the control group revealed 37.7 percent.