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흰쥐에서 동맥혈만 공급한 보조간 이식에 관한 연구(Ⅱ)
羅成均 中央醫學社 1976 中央醫學 Vol.31 No.1
In order to asses that the hepatic arterial blood alone can maintain the function of the heterotopic auxiliary liver graft in rats, guanine aminohydrolase (GDA) GPT, and GOT activities as well as nucleic acids were, analyzed in the graft. Isogenie and allogeneic liver transplantation were performed on Lewis and Sprague-Dawley rats respectively, weighing 250 to 300 gm by the suture technique of Lee's original method, but only arterial blood flow was introduced to the graft and the bile duct was implanted into the duodenum. All'hepatic isografts in these experiments were removed 1, 4, 5, 6,10, and 13 (days subsequent to the surgical ,procedure for biochemical studies, and for histo?pathological studies-in the grafts allogeneic liver transplant rats were also sacrificed for periods up to 14 days. The following results were obtained. I .Biochemical studies 1), DNA. contents were decreased, with slight increases on the 5th postoperative day. 2) RNA contents showed also decreases, except slight increases on the 5th postoperative day. 3) GDA activities were also decreased, maximally oil the 5th postoperative day, but progressive increases were evident on the 13th postoperative day. 4) ,GPT & GOT activities showed marked decreases. Histopaaholoical studies: n observation period the graft shod-ed to slight increase on the DLIi postopu ative day 2), Some of the grafts revealed findings of rejection, outflow blurb, in flamma Lion and/or infection, or combined features of them. It is concluded that the. hepatic arterial blood can maintain minimal liver fu?nction, but have no apparant regeneration,power, in the isogeneic liver graft. The histopathological study in the allogenic liver graft discloses the findings, of rejection, outflow,block, inflammation, ischemia and combined features of them.
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장결핵 (腸結核 ) 34예에 대한 임상적 (臨床的) 고찰
김상준,김우길,이수석,라성균,장선택 ( Sang Jhoon Kim,Woo Kil Kim,Su Suk Lee,Rha Sung Kyun,Sun Taik Chang ) 대한소화기학회 1974 대한소화기학회지 Vol.6 No.2
Levy and Granmark had introduced double contrast study in 1896 for the first time. Since Daval and Beclere had human experiment of double contrast air study, so many methods for diagnosis of ge.stric diseases are discovered and improved. 'Aiain valuable purpcses for double contrast study of stomach and duodenum are early diagncsis of stomach cBilcer and differectial diagncsis of ulcer forming malignancy frcm benigncy. In ='d ticn to t4ese, differentiation of gastroauoe.al defects, intrin-ic or extrins!c, is also v'orthwlii!e by tl;e metho3 of doub!e cc,ntrast air study of stomach and duodenum. Hvpotonic duodenography is exclusive of misinterpretation of duocenal non lesion in conventi,.nal barium study, as it attributes in cor firmation of nature, extention of lesion, and differer..iation betv;een intrinsic or extrinsic, cr duodenal or papillary lesion in origin, Hypotonic 3uodenogrzphy is helpful in carly diagnosis of disease and avoid misleading unneccessary fv.rther study or explorat- ory laparotomy.
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