성문상부암(聲門上部癌)의 근치적(根治的) 방사선치료(放射線治療) 성적(成績)

김귀언,서창옥,김병수,김광문,홍원표,Kim G.E.,Suh C.O.,Kim B.S.,Kim K.M.,Hong W.P. 대한두경부종양학회 1985 대한두경부 종양학회지 Vol.1 No.1

A total of eighty five cases with supraglottic carcinoma treated by radical radiotherapy in Yonsei Cancer Center between Jan. 1974 and Dec. 1980, was observed through retrospective analysis. This study is concerned wi th patients selection for irradiation alone or combined treatment with surgery. Emphasis is directed to the analysis of effectiveness of radical radiotherapy instead of partial laryngectomy in T-1, T-2 and early T-3 lesion. A satisfactory control of laryngeal disease and preservation of a normal voice ranging from 100% for $T_1N_0$ lesions, 61.1% for $T_2N_0$ to 50% for $T_3N_0$. But 47.1% of cases with node metastasis on admission had poor results to irradiation suggesting of necessicity of combined treatment. 5 year recurrence-free survivals was 43.3% in all cases with supraglottic carcinoma treated by irradiation alone, although it was 87.5% in T-1 and 51.8% in T-2.

Localized Primary Laryngeal Lymphoma Treated by Irradiation

김귀언(G E Kim),서창옥(C O Suh),김주항(J H Kim),김병수(B S Kim),이광길(K K Lee),김광문(K M Kim),홍원표(W P Hong) 대한두경부종양학회 1985 대한두경부 종양학회지 Vol.1 No.1

A case of primary laryngeal non -Hodgkin's lymphoma is detailed with a review of the literature, on this rare site of presentation. Histologic findings and radio-therapeutic technique are included with longterm follow-up data. Local radiotherapy is a curative treatment of choice due to longterm NED survival with preservation of voice.

고선량율 강내조사법을 이용한 자궁경암의 방사선 치료

김귀언(G.E. Kim) 대한방사선종양학회 1983 Radiation Oncology Journal Vol.1 No.1

根源不明 轉移性 頸部癌의 治療

金貴彦(G.E. Kim) 대한방사선종양학회 1984 Radiation Oncology Journal Vol.2 No.1

聲門上部癌의 根治的 放射線治療 成績

G E Kim(金貴彦),C O Suh(徐昌玉),B S Kim(金炳洙),K M Kim(金光文),W P Hong(洪元杓) 대한두경부종양학회 1985 대한두경부 종양학회지 Vol.1 No.1

A total of eighty five cases with supraglottic carcinoma treated by radical radiotherapy in Yonsei Cancer Center between Jan. 1974 and Dec. 1980, was observed through retrospective analysis. This study is concerned with patients selection for irradiation alone or com bined treatment with surgery. Emphasis is directed to the analysis of effective ness of radical radiotherapy instead of partial laryngectomy in T - 1. T - 2 and early T - 3 lesion. A satisfactory control of laryngeal disease and preservation of a normal voice ranging from 100% for T1 N0 lesions, 61.1 % for T2 N0 to 50% for T3N0. But 47.1% of cases with node metastasis on admission had poor results to irradiation suggesting of necessicity of combined treatment. 5 year recurrence - free survivals was 43.3% in all cases with supraglottic carcinoma treated by irradiation alone, although it was 87'5% in T - 1 and 51.8% in T - 2.

두경부에 발생한 연골육종 4예

고은희(E H Koh),노준규(J K Loh),김귀언(G E Kim),서창옥(C O Suh),김수곤(S K Kim),김병수(B S Kim),홍원표(W P Hong),박경란(K R Park),이창걸(C G Lee) 대한두경부종양학회 1987 대한두경부 종양학회지 Vol.3 No.1

Chondrosarcoma of the head and neck is very rare tumor and this incidence was reported to be about 10% of all chondrosarcomas. Maxilla is the most common site of involvement and mandible, paransal sinus, nasal cavity and base of skull in that order. In general, chondrosarcoma has been known to be radioresistant, however since the Princess Margaret Hospital reported that it was radioresponsive tumor in 1980, the role of radiotherapy has been emphasized in terms of local control, especially in head and neck regions where complete excion is often difficult to achieve. The authors experienced 4 cases of chondrosarcoma of head and neck among all 29 chondrosarcoma patients from 1971 to 1985. The clinical and pathologic feature of this disease, it's treatment and prognosis were reviewed along with the literatures.

Radiation Treatment of Esophageal Cancer

오원용,서창옥,김귀언,Oh W. Y.,Suh C. O.,Kim G. E. The Korean Society for Radiation Oncology 1985 Radiation Oncology Journal Vol.3 No.1

한국에서는 식도암의 임상적 관찰과 치료성적이 아직까지는 광범위하게 연구 및 보고되지 않았지만, 소화기계통에서 발생하는 악성종양 중에서는 비교적 적지 않은 것으로 알려져 있다. 의학적 지식, 진단적 설비, 방사선 치료의 적용, 외과적 수술의 진보, 그리고 최근의 화학요법의 재발 등과 같은 괄목할만한 향상에도 불구하고 예후는 극히 불량하여 5년 생존율이 10%이하로서, 과거에 비하여 크게 향상되지 않은 것으로 보고되고 있다. 이에 저자들은 1970년 1월부터 1980년 12월까지 만 11년 동안 식도암으로 진단되어 연세 암 센터에서 근치적 목적으로 방사선 치료를 받았던 63예에 대한 철저한 추적조사를 통하여 후향성 분석을 시행한 바 다음과 같은 결과를 얻었다. 1. 전 63예의 식도암 환자의 85.2%인 52예는 조직병리학적 소견에서 상피성세포암(Epidermoid Carcinoma)으로 확진되었다. 그리고 $T_1$인 17예를 제외한 46예73%의 병변은 상당히 진행되였던 예들이였다. 2. 방사선 조사선량은 일일 일회 2Gys가 조사되였으며 총 조사선량 $50{\sim}74Gys$가 $5{\sim}8$주간에 조사되었다. 3. 전 63예중 28예에서 방사선 치료 후 1개월만에 식도조형상을 통하여 식도암에 대한 방사선치료 효과를 평가하여 본 결과, 완전관해는 7예였으며 나머지 15예는 부분적 관해, 그리고 6예는 변화가 없었다. 4. 전 63예의 3년, 5년 생존율은 11.8%, 8.8%였으며 그리고 $T_1$인 17예의 3년, 5년 생존율은 24.7%, 20.8%였다. 63 patients who were irradiated with a goal of long term control among 101 patients with esophageal cancer seen during an 11 fears period between Jan, 1970 and Dec, 1980 at Yonsei Cancer Center in Seoul, Korea have retrospectively analysed. 52(82.5%) among the 63 Patients were confirmed to have epidermoid carcinoma in the histology. 46 cases(73.0%) except 17 cases of $T_1$, were locally or far advanced extension. Tumor dose of radical radiation in the management of esophageal cancer had delivered from 50 Gy to 74 Gys. 2 Gys daily fractions, between 5weeks and 8 weeks. After 1 month from the completion of radiation, 23 of the 63 patients had a repeat barium esophagogram for the assessment of tumor response, there had showed 7 cases of complete response and 15 cases of partial response. 45(71.4%) patients were followed up and the remaining 18 patients were lost to follow-up within 1 year after the completion of irradiation. Actuarial overall 3 and 5 years survival rate of all 63 Patients were 11.8% and 8.8%, respectively. The actuarial 3 and 5 years survival rates of 17 cases of $T_1$, esophageal cancer were 24.7% and 20.8%. Statistically, there was no significant difference in survival rate according to tumor location (p>0.05). Radical Radiotherapy, Esophageal Cancer

병기 T₁ 성대종양 환자의 방사선치료성적에 관한 고찰

이연구(Y G Lee),노준규(J K Loh),이창걸(C G Lee),이종영(J Y Lee),김귀언(G E Kim),서창옥(C O Suh),홍원표(W P Houng) 대한두경부종양학회 1988 대한두경부 종양학회지 Vol.4 No.1

Radiation therapy is generally considered to be the treatment of choice in T₁ glottic cancer, maninly because of preservation of voice function and its local control rate is comparable to that of surgery. Failures from radiation therapy can be ultimately salvaged by surgery. A retrospective analysis of the treatment of 25 patients with T₁ glottic cancer seen at the Y onsei Cancer Center from 1980 to 1984 is presented. Radiation dose to the target volume varied from 6400 to 7000 cGy in 6-7 weeks. The local control rate is 84%. Four patients had primary failure and three of these patients had salvage surgery. Of the 3 patients who had salvage surgery, 2 were cured and aonther one was died with progression of the disease. 5-year acturial and disease free survival rate are 91.1%, 78.0% respectively.

두경부에 국한된 Stage I, II, Non-Hodgkin's Lymphoma의 방사선치료

오원용,서창옥,김귀언,김병수,Oh W. Y.,Suh C. O.,Kim G. E.,Kim B. S. 대한방사선종양학회 1984 Radiation Oncology Journal Vol.2 No.1

53 patients of previously untreated Stage I&II Non-Hodgkin's Lymphoma in head and neck treated with irradiation at Yonsei Cancer Center from January, 1970 to December, 1978 were retrospectively analysed. 5 year survival rate and 5 year disease free survival rate were $51.5\%\;and\;42\%$. Local control rate by irradiation was $92.4\%$ with mainly $4,000\~6,000$ rads. 21 patients suffered relapses after radiotherapy, 4 cases recurred within irradiated area, 4 cases at contiguous site of irradiation field, and 13 cases recurred at distant area, more commonly below diaphragm. Most cases relapsed within 1 year 6 months after treatment. Optimum irradiation field for head and neck localized lymphoma, prognostic factors ana usefulness of chemotherapy are also discussed.

THYMOMA : A Review of Fourteen Patients

S.K. Kim(김수곤),H.S. Lee(이형식),K.H. Cho(조관호),C.O. Suh(서창옥),G.E. Kim(김귀언) 대한방사선종양학회 1985 Radiation Oncology Journal Vol.3 No.1

흉선종은 비교적 드문 종양으로 알려져 있다. 예후를 알 수 있는 가장 중요한 인자는 수술시 육안적인 종양의 침윤정도이며, 치료는 수술에 의한 종양의 제거가 무엇보다 중요하고, 방사선 치료 역시 수출 후 국소적 계발의 방지를 위해 쓰이고 있다. 근치적 목적의 방사선 치료도 수술이 어려운 경우에 시행되고 있는 형편이다. 저자들은 1977년 1월부터 1984년 12월까지 세브란스병원 연세암센타 치료방사선과에서 흉선종 진단받고 치료한 14명의 환자를 후향성 분석에 의해 다음과 같은 결과를 얻었다. 1. 6명의 환자(14%)가 근무력증을 나타냈다. 2. 주변조직의 침윤이 86%(12/14)에서 관찰되었다. 3. 43%에서 육안적 완전 절제를 시행하였고 14%에서 부분결제, 그리고 43%에서는 생검만 시행 하였다. 4. 수술 후 혹은 근치적 목적의 방사선치료는 8명의 환자에서 시행하였으며 그중 현재 5명은 생존(4년, 2.8년, 1.6년, 1.4년, 1.3년), 3명은 사망(1년, 0.6년, 0.6년)하였다. 5. 방사선 치료선량은 대체료 4,000 ~ 4,500rad(1950 ~ 7,000rad)를 전후 흉곽 부위에 외부 조사하였다. Between January 1977 and December 1984, fourteen patients diagnosed of thymoma has been analyzed retorspectively. Six patients(6/14 patients 43%) had myasthenia gravis. Twelve patients (12/14 patients 86%) had invasive thymoma. Complete resection was carried out in six patients (43%), two patients had patial resection (14%) and six patients had only biopsy (43%). Postoprative or radical radiotherapy was given to 8 patients, of whom 5 patients was still alive(4 yr. 2.8 yr. 1.6 yr. 1.4 yr. 1.3 yr) and 3 patients died (1 yr. 0.6 yr. 0.6yr). External irradiation ranges 1950 ~ 7000 rads(mean 4500, median 4000 rads).