공복혈당과 당화혈색소를 적용한 당뇨병 이상소견자의 분포 및 특성 - 당뇨병 기진단자를 제외한 성인을 대상으로

권세영,나영악,Kwon, Seyoung,Na, Youngak 대한임상검사과학회 2017 대한임상검사과학회지(KJCLS) Vol.49 No.3

Among the commonly known tools to diagnose diabetes are fasting plasma glucose (FPG), HbA1c., and OGTT known as gold standard. However, there can be many disagreements on the ways to diagnose diabetes. In this study, we examined the differences of the types of diabetes according to the applicability of FPG and HbA1c. Moreover, we evaluated the concordance of diagnosis. We excluded subjects with missing glucose and HbA1c data, as well as those previously diagnosed with diabetes, and those who fasted less than 8 hours. The data of 4,502 subjects (1,956 men and 2,546 women) from the 2015 KNHNES were analyzed. We divided these patients into three categories which are normal, prediabetes, and diabetes, based on the FPG and HbA1c. In men, the number of subjects with FPG ranging from 100 to 125 mg/dL and HbA1c ${\geq}6.5%$ was 23 out of 664, and the number of subjects with FPG < 126 mg/dL and HbA1c ${\geq}6.5%$ was 39 out of 86 newly diagnosed diabetes patients. The concordance rate was as follows: Normal 80.3%, prediabetes 44.9%, and diabetes 54.7%. The coefficient of Cohen's Kappa was 0.322 in men and 0.362 in women; this suggests that both gender showed a low concordance rate. However, when we divided them into two categories (nondiabetes and diabetes), Kappa was 0.582 in men and 0.637 in women, showing a relatively high concordance rate. While all subjects with FPG ${\geq}126mg/dL$ showed a significantly high HOMA IR, all subjects with FPG < 126 mg/dL showed a significantly high QUICKI. Considering the low concordance rate for the diagnosis of diabetes and characteristic of diagnostic tests, it is necessary to combine the related tests for diagnosing diabetes.

우리나라 청소년에서 혈청과 뇨의 크레아티닌 농도

권세영,나영악 대한임상검사과학회 2014 대한임상검사과학회지(KJCLS) Vol.46 No.4

Creatinine is a general marker as a screening test for renal disease. This study was conducted to provide basic data about pediatric concentration for serum and urine creatinine. The data from the 2011 Korean National Health and Nutrition Examination Survey was used. Analysis was done on 488 Children and Adolescents (boys 278, girls 210) aged 10 to 19, the Jaffe reaction method was used to gather the data. The highest serum creatinine levels were found in boys aged 19 to 20 years, the mean being 0.97 mg/dL (min 0.81 mg/dL, max 1.14 mg/dL). The levels showed increase over those in the 10 year old group. The highest urine creatinine levels were found aged 19 to 20 years, and the mean was 222.68 mg/dL (min 133 mg/dL, max 324 mg/dL). In the case of girls, the highest serum creatinine levels were found with those aged between 18 and 19, the mean being 0.71 mg/dL (min 0.49 mg/dL, max 0.84 mg/dL). The levels showed increase over the 11 to 18 year old group. The highest urine creatinine levels were found aged 14 to 15 years, and the mean was 218.44 mg/dL (min 131 mg/dL, max 321 mg/dL). The mean difference in serum creatinine in all age groups was statistically significant except for those aged 10 to 14, that of urine creatinine in all age groups was not significant statistically except for those aged 12 to 13, 17 to 18. Therefore, it is suggested that reference values for children and adolescents should be divided into different groups according to gender, further studies are needed using complementing data of the pediatrics.

소아청소년에서 혈청 25-hydroxyvitaminD 농도와 비타민 D 상태

권세영 사단법인 대한보건협회 2023 대한보건연구 Vol.49 No.2

Objectives: Vitamin D deficiency has become one of the most important health issues, especially in children and adolescents. This study was conducted to provide basic data about pediatric intervals for 25-hydroxyvitamin D[25(OH)D]. Methods: The data from the 2008~2014 Korean National Health and Nutrition Examination Survey was used. Analysis was done for 5,137 Children and Adolescents(boys 2,735, girls 2,402) aged 10 to 18. The method of radioimmunoassy was used to get the data. Results: Mean serum 25(OH)D value was 17.05ng/mL which was higher in boys than in girls. The highest 25(OH)D level was found in boys aged 10, and the lowest 25(OH)D level was found in girls aged 18. The range of 25(OH)D levels of subjects aged 10 was as follows; the 2.5th, 25th, 50th, 75th and 97.5th percentile values were 9.99, 16.19, 19.41, 23.33 and 34.13ng/mL respectively. The ratio of vitamin D deficiency was higher in girls than in boys (79.0% vs 68.6%) and increased according to age. Conclusion: It is considered necessary to study the determination of serum vitamin D status by applying appropriate criteria and the reference value for serum 25OHD concentration. 연구목적: 비타민 D 결핍은 특히 어린이와 청소년에서 중요한 건강 문제 중 하나가 되었다. 본 연구는 소아청소년의 25-하이드록시비타민 D[25(OH)D]의 농도에 대한 기초 자료를 제공하기 위해 수행되었다. 연구방법: 2008∼2014년 국민건강영양조사 자료를 사용하였고, 10∼18세 소아청소년 5,137명(남자 2,735명, 여자 2,402명)을 대상으로 분석하였다. 혈청 25(OH)D 측정치는 방사면역측정법을 이용하였다. 연구결과: 평균 혈청 25(OH)D 값은 17.05ng/mL로 여아보다 남아에서 더 높았다. 25(OH)D 수치는 10세 남아에서 가장 높았고, 18세 여아에서 가장 낮았다. 10세 남아에서 25(OH)D의 2.5th, 25th, 50th, 75th 및 97.5th 백분위수 값은 각각 9.99, 16.19, 19.41, 23.33 및 34.13ng/mL였다. 비타민 D 결핍 비율은 남아(68.6%)보다 여아(79.0%)에서 더 높았고, 연령에 따라 증가하였다. 결론: 혈청 25OHD 농도에 대한 적절한 기준과 참고범위를 적용하여 비타민 D 상태를 판단하는 연구가 필요할 것으로 생각된다.

Anaerobic Baffled Reactor를 이용한 1차 슬러지 산발효 및 후탈질 공정을 위한 외부탄소원으로의 적용 가능성 연구

권세영,조진우,신정훈 한국폐기물자원순환학회 2014 한국폐기물자원순환학회 학술대회 Vol.2014 No.11

Anaerobic Baffled Reactor(ABR)는 혐기성 소화 공정 중 하나로 주로 중소규모의 폐수처리에 사용되며 반응조 내부에 설치된 격벽(Baffle)에 의해 산생성과 메탄생성의 공간적 분리가 뚜렷하고, 일정 수준의 고액분리 효과를 기대할 수 있으며, 비교적 짧은 HRT(Hydraulic Retention Time)와 긴 SRT(Solids Retention Time)를 유지할 수 있다는 장점이 있다. 본 연구에서는 ABR 공정을 이용하여 하수처리공정에서 발생하는 1차 슬러지를 안정화시키는 과정에서 메탄생성을 억제하고 산생성을 최대화하여 고농도의 유기산(Volatile Fatty Acid, VFA)을 생산하고자 하였다. 이때 생산되는 유기산은 후단 탈질반응조의 외부 탄소원으로 이용되어 후탈질 공정으로 유입되는 고농도의 NO3-N을 제거하도록 하였다. 최적 설계 인자 도출을 위하여 ABR 형태의 산발효조와 탈질반응조의 HRT, SRT 및 슬러지 반송과 폐기량이 VFA 생성 및 탈질에 미치는 영향을 살펴보았다. 실험실 규모의 연구결과 HRT 2, 4, 6 및 8일에서 ABR공정을 통한 1차 슬러지 유입 SCOD대비 VFA 생성율은 각각 107±121, 35±87, -82±9 및 -82±12%로 HRT 2일에서 가장 높은 산 생성율을 나타내었으며, HRT 6일 및 8일에서는 긴 체류시간으로 인해 생성된 유기산의 상당량이 메탄으로 전환되면서 VFA 생성율이 저하되는 결과를 보였다. 또한 각 조건에서 생산되는 VFA를 탈질반응조의 유입탄소원으로 이용하였을 때, 유입되는 SCOD의 70% 이상이 탈질에 사용되었으며, NO3-N의 제거율은 평균 82±11% 수준의 탈질효율을 확인하였다.

북한이탈주민 작가 이항구의 『소설 김일성』연구

권세영,이미림 한중인문학회 2012 한중인문학회 학술대회 Vol.2012 No.1

작업의 특징적인 특성에 따른 톨루엔 노출 근로자에서 요중 마뇨 산의 농도

권세영,나영악,김상락 대한임상검사과학회 2012 대한임상검사과학회지(KJCLS) Vol.44 No.1

This study is assessed the urinary hippuric acid (HA) concentration in toluene-exposed workers. Toluene is widely used in the coating, printing, painting and petroleum industries. We analyzed the hippuric acid level of toluene-exposed workers (males: 198, females: 63) from 2008 to 2010 and examined the relationship between hippuric acid and the characteristics of their work. The measurements of the urinary hippuric acid were confirmed by high-performance liquid chromatography. Among the subjects, males had on average more work experience than females (males: 9.17 years, females: 4.45 years), but females showed a higher hippuric acid concentration levels than males (males: 0.26 g/L, females: 0.75 g/L). The mean of the HA concentration according to the age group was 0.19 g/L in 30’s, 0.30 g/L in 40’s, 0.54 g/L in 50’s, 1.36 g/L in 60’s. Those in their 60’s had the highest concentration. The mean of HA concentration according to the type of work was 0.70 g/L for the coating, 0.52 g/L for the painting, and 0.16 g/L for the printing industries, revealing that the workers in the coating industry had the highest concentration. By the highest order, the mean of HA concentration by working period was as follows; less than 5 years, ≤5 years~<10 years. The factors that influence the HA concentration are not only how long one is exposed to toluene but also the type of work, worker’s age, and their gender. .

델파이(Dephi)와 계층 분석적 의사결정(AHP) 기법을 활용한 댄스 피트니스 강습 전략 개발

권세영,전원재 한국체육정책학회 2021 한국체육정책학회지 Vol.19 No.4

In this study, Delphi and AHP techniques were applied to explore effective dance fitness teaching strategies. A total of 20 experts were selected as a group of experts, mainly field experts and academic experts. Data were collected by conducting a total of three surveys and analyzed through the Expert Choice 2000 program. The research results are as follows. First, as a result of the Delphi study, there were largely 4 factors in the large category, 11 factors in the middle category, and 34 factors in the small category. Second, the relative weights and priorities were derived through the results of the Analytic Hierarchy Process(AHP) study. The findings are of great significance in it presented objective indicators of teaching strategies required in the dance fitness field.

한국 소설의 중국어 번역 검토를 통한 번역 지원 사업의 개선 방안 - 김유정 단편소설의 중국어 번역물을 분석을 통해

권세영 한중인문학회 2016 한중인문학회 국제학술대회 Vol.2016 No.06

감독 권력에 대한 대학 엘리트 여성축구선수의 순응

권세영,임수원 한국스포츠사회학회 2012 한국스포츠사회학회지 Vol.25 No.4

The purpose of this study was to find out docility aspect of college elite female football players to the power of head coach. For this purpose, a case study of qualitative research methods were used. Environment of this study was ‘Y’ college women's football team in ‘D’ city. We selected as 10 participants in the research by using purposeful sampling. The data was collected through non-participant observation, in-depth interviews, other related materials. As a result of textual analysis in the view of Michel Foucault's discipline power, docility aspect of college female football players to the power of head coach is as follows: First, the visible eye consciousness of head coach at the stadium and training space. Second, norm internalization by head coach. Third, perception of head coach's assessment and secure the opportunity to play in the game. Fourth, employment obsession and self-surveillance. Fifth, routine of the discipline due to a long-term camp. Sixth, acceptance of hierarchy consciousness and obedience culture. According to the results of the study, in-depth research into the culture of resistance as well as docility needs to be deployed in terms of ensuring a balanced perspective on the relationships power of human. 본 연구는 축구 감독 권력에 대한 대학 엘리트 여성축구선수들의 순응 기제를 밝히는데 그 목적이 있다. 이를 위해 질적연구 방법 중 사례연구를 이용하였다. 연구의 환경은 ‘D’광역시 ‘Y’대학 여자축구 팀이었으며, 연구참여자는 10명이었다. 자료는 비참여관찰과 심층면담, 기타 관련 자료 등을 통해 수집되었다. 푸코의 규율권력 관점에서 접근하여 텍스트 분석을 통해 도출된 결과, 대학 엘리트 여성축구선수들이 감독의 권력에 순응하는 기제는 첫째, 경기장 및 훈련공간에서 감독의 가시적 시선 의식 둘째, 감독에 의한 규범 내면화 셋째, 감독의 평가 인지와 경기출전 기회 확보 넷째, 취업 강박관념과 자기감시 다섯째, 장기적인 합숙으로 인한 규율의 일상화 여섯째, 위계질서 의식과 복종문화 수용 등 6가지로 나타났다. 이상의 연구결과 인간의 관계권력에 대한 균형적인 시각을 확보해야 한다는 측면에서 순응뿐 아니라 저항문화에 대한 심층적인 연구가 전개될 필요가 있을 것으로 사료된다.

인슐린 저항과 B세포 기능이 당뇨병이 없는 성인의 항상성 모델 평가에 의해 결정되는 것에 대한 상대적 요인

권세영,나영악 대한임상검사과학회 2013 대한임상검사과학회지(KJCLS) Vol.45 No.4

Insulin resistance and pancreatic beta cell dysfunction have been established as being related to the diabetes. Lately, what is emphasizing is that those have been shown as something related to the metabolic syndrome and cardiovascular disease. Homeostasis model assessment (HOMA), simple index is calculated on blood levels of fasting glucose and insulin. And HOMA has been widely validated and applied for insulin resistance and pancreatic beta cell dysfunction. We also assessed the factors relative to insulin resistance and β cell function determined by HOMA. The data from the 2010 Korean National Health and Nutrition Examination Survey were used. Analysis was done for 3,465 nondiabetic subjects (male 1,357, female 2,108). At baseline, anthropometric measurements were done and fasting glucose, insulin, lipid (Total cholesterol, HDL cholesterol, LDL cholesterol and Triglycerides) profiles were measured. HOMA-insulin resistance (HOMA-IR) and beta cell function (HOMA β-cell) were calculated from fasting glucose and insulin levels. In male, the value of HOMA-IR and HOMA β-cell was the highest among 30's and decreased as the age increased. In female, the value of HOMA-IR increased with age, while HOMA β-cell decreased. High HOMA-IR and low HOMA β-cell were associated with the highest value of fasting glucose and systolic blood pressure. Low HOMA-IR and high HOMA β-cell showed the lowest concentration of fasting glucose and the highest concentration of HDL cholesterol. High HOMA-IR and high HOMA β-cell were connected with BMI, Total cholesterol, LDL cholesterol, and Triglycerides. There was a negative correlation between HOMA β-cell and age. The correlation coefficients of HOMA-IR and HOMA β-cell showed the highest value among weight, BMI and WC.