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공태석 ( Tae Seok Kong ),한태영 ( Tae Young Han ),이현경 ( June Hyunkyung Lee ),손숙자 ( Sook-Ja Son ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.1
Pacinian neuroma is a rare skin disease characterized by hyperplasia or hypertrophy of the Vater-Pacini corpuscles which are responsible for the appreciation of deep pressure and vibration. It usually affects the volar aspects of the fingers in middle-aged adults and it produces severe pain and tenderness on the affected skins. About half of previously reported cases revealed the association with precipitating factors such as local trauma, but underlying mechanisms are not established. Two patients presented with a several months history of solitary pale-colored papule on the tip of finger. The patients reported a severe tenderness on the lesion with a history of repetitive trauma. The histopathologic examination from the lesions showed increased number of onion-like stratified structures around nerve fibers, compared to the usual density of pacinian corpuscles (3∼5/cm2). The histopathological features were consistent with pacinian neuroma. The symptoms of the patients disappeared soon after the surgery. Herein, we present two patients with pacinian neuroma on the finger, and we also propose that pacinian neuroma should be considered for the differential diagnosis of tender papule on the digit.
혈액학적 이상 소견이 없는 환자에서 발생한 조직구양 Sweet 증후군
공태석 ( Tae Seok Kong ),한태영 ( Tae Young Han ),이현경 ( June Hyunkyung Lee ),손숙자 ( Sook Ja Son ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.7
Histiocytoid Sweet syndrome (HSS) is a recently described rare variant of acute febrile neutrophilic dermatosis. HSS is clinically characterized by painful inflammatory plaques or nodules with high fever and neutrophilia. About 20% of HSS patients also have an associated malignancy, most commonly of hematologic origin. Histopathologically, HSS is characterized by dense histiocytic infiltration with prominent upper dermal edema, and little neutrophil infiltration. A 69-year-old female presented with a 1-week history of painful erythematous plaques on both elbows accompanied by fever. She was diagnosed with acute pyelonephritis and treated with ciprofloxacin for 2 weeks. Routine laboratory tests showed elevated white blood cell count (predominantly neutrophils), erythrocyte sedimentation rate, C-Reactive Protein, and a mildly elevated liver function test. Peripheral blood smears were normal. Histopathologic examination showed papillary dermal edema and diffuse interstitial infiltration of histiocytoid cells. Immunohistochemical studies revealed that the histiocytoid cells were positive for CD 68 and myeloperoxidase. After treatment with systemic glucocorticoids, the skin lesions and fever gradually resolved. Based on the clinical and histopathologic examination, we diagnosed HSS with no evidence of a hematologic disorder. Herein, we report an unusual case of HSS without associated bone marrow dysplasia. (Korean J Dermatol 2015;53(7):552∼555)
변희섭,오승원,공태석,김종만 한국산림바이오에너지학회 2002 산림바이오에너지 Vol.21 No.3
본 연구는 단소용 대나무 악기재를 효과적으로 건조하기 위하여 열처리 및 몇 가지 스케줄에 의한 건조를 실시하였다. 평균 직경 2.2cm, 길이 60cm정도의 솜대를 이용하였다. 열처리 효과를 평가하기 위하여 무처리 및 열처리재로 구분하였으며 적당한 건조 조건 조사를 위해서 20℃, 65%와 40℃, 40% 그리고 대기상태의 3가지 조건으로 실시하였다. 탄화와 재색의 결함이 발생하지 않는 열처리의 최적 온도 조건은 180℃정도가 적당하였으며 열처리가 할렬의 수와 할렬 크기의 발생을 줄였으며 건조결함을 발생하지 않는 최적의 조건은 온도 20℃, 관계습도 65%이지만 건조를 할 때 기간이 너무 많이 소요되는 단점이 있기 때문에 40℃, 40%에서 건조시키는 것이 더욱 효율적이었다. This study was carried out to investigate a heat treatment condition and suitable drying schedule of bamboo material(Phyllostachys nigra var. henonis) for a vertical flute with small-notched bamboo. It is very important to prevent drying defects during its drying process. We investigated the effort of heat treatment the most suitable drying schedule for small-notched bamboo vertical flute without drying defects in this research. A direct heat treatment method and drying conditions of 3($20^{\circ}C$ 65%, $40^{\circ}C$ 40%, and dry at air condition) were applied to the Bamboo specimen that felled in several areas for a month. The result suggested that the most suitable drying schedule with the less split and the shortest time was to dry at $40^{\circ}C$, 40% condition and it was useful to direct heat-treatment because of reducing the number and size of split during drying bamboo.
김서완 ( Seo Wan Kim ),공태석 ( Tae Seok Kong ),한태영 ( Tae Young Han ),이현경 ( Hyun Kyung Lee ),손숙자 ( Sook Ja Son ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.11
Granulomatous vulvitis is a rare localized inflammatory disease characterized by a painless, swollen, indurated and distorted vulva. Histopathologically, it shows chronic non-necrotizing granulomatous inflammation with edema, fibrosis, and lymphangiectasia. Some cases are associated with granulomatous cheilitis or Crohn`s disease. So far, only a few cases of idiopathic granulomatous vulvitis have been reported. A 43-year-old female presented with a 1-year-history of persistent swelling of the vulva. The lesion was enlarged, edematous, and indurated, and there were clustered vesicles and papules on the labia major. Histopathologic examination of the swollen labia major showed granulomatous inflammation composed of multinucleated giant cells and epithelioid cells, with numerous lymphocytes in the dermis. Another biopsy specimen obtained from the clustered vesicles showed lymphangiectasia with chronic inflammation. Based on these characteristic histopathologic features and clinical findings, the patient was diagnosed with idiopathic granulomatous vulvitis. Herein, we reported a rare case of idiopathic granulomatous vulvitis that developed in a healthy woman. (Korean J Dermatol 2013;51(11):912∼915)
김서완 ( Seo Wan Kim ),공태석 ( Tae Seok Kong ),한태영 ( Tae Young Han ),이현경 ( June Hyunkyung Lee ),손숙자 ( Sook Ja Son ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.12
Partial unilateral lentiginosis is a rare pigmentary disorder which is characterized by multiple grouped lentigines in unilateral or segmental distributions. The ocular involvement of the disease is extremely rare and only four cases have been reported until today. The exact pathophysiology is still unknown. An 18-year-old woman is being presented with unilateral hyperpigmented macules on her left forehead, eyelid, cheek, lip and chin which all demarcated sharply at the midline of her face. The lesion has been presented since the age of 1. Also, there are discrete brownish pigmentations on her left bulbar conjunctiva. Biopsy specimen is being obtained from the left chin and the histopathological examinations revealed increasing basal layer of pigmentations and mild elongation of rete ridges. The histopathological features are also consistent with lentigo simplex. Herein, we present a rare case of partial unilateral lentiginosis with an ocular involvement. We have also proposed that the partial unilateral lentiginosis has a possibility of ocular involvements. (Korean J Dermatol 2013;51(12):979∼982)
영아에서 BCG 접종 후 발생한 전신성 고리 육아종 3예
김서완 ( Seo Wan Kim ),공태석 ( Tae Seok Kong ),한태영 ( Tae Young Han ),이현경 ( June Hyunkyung Lee ),손숙자 ( Sook Ja Son ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.4
Generalized granuloma annulare is a rare benign granulomatous dermatosis characterized by disseminated necrobioticdermal papules forming an annular or nonannular configuration. It usually occurs in adults and rarely affects infants. Histologically, it presents as a lymphohistiocytic granuloma associated with varying degrees of connective tissue degeneration. Clinical associations between generalized granuloma annulare and diabetes mellitus, thyroid disease,malignancy, infection, and vaccination have been reported. There are a few cases reports of generalized granulomaannulare associated with Bacillus Calmette-Guerin (BCG) vaccination. Herein, we report three cases of generalizedgranuloma annulare following BCG vaccination in infants.