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60 N.m급 플렉서블 디스크 커플링 구조해석 및 최적화
이현규(H. K. Lee),김병로(B. R. Kim),김성묵(S. M. Kim),김종봉(J. B. Kim) 한국생산제조학회 2013 한국생산제조학회지 Vol.22 No.5
A structural analysis was carried out for a 60 N.m class flexible disk coupling. Flexible disk couplings are used to transmit power between two shafts. When a flexible coupling is used, some amount of misalignments such as angle of deviation and end play can be allowed in assembling the shafts. However, the maximum allowable misalignment should be decided to guarantee the fatigue life. In this study, the effect of the angle of deviation and end play on the maximum stress was investigated. From the analysis results, it was shown that the angle of deviation has a greater effect on the maximum stress than the end play. Furthermore, the dimensions of the disk plate were optimized to realize a better design. From the optimization, the maximum stress could be reduced by up to 5.2%.
Interleukin - 2 와 Cycolphosphamide 를 이용한 말기암 환자 치료
최승훈(S H Choi),임태숙(T S Lim),김병로(B R Kim),박기일(K L Park),이경식(K D Lee),함경수(K S Hahm),나도선(D S Na),한문희(M H Han) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.4
N/A Application of adoptive immunotherapy has been the inability to generate specifically sensitized lymphoid cells with antitumor reactivity. Interleukin-2 is now available in large quantities and has made possible expansion of cells with a diverse spectrum of immune reactivities. In this study, we evaluated the immunologic effects and the response rate of LAK cell, Interleukin-2 and cyclophosphamide administered intravenously in humans with tumors unresponsive to other treatments. There were five hepatomas and a metastatic breast cnacer. Two patients received LAK cell and Interleukin-2 twice. 5.94x10 monounclear cells were obtained in each leukapheresis. Cellular cytotoxicity was measured using 51 Chromium release assay. This study clearly showed that Interleukin-2 and Cyclophosphamide treatment augmented LAK cell activity, but there were no statistically significant differences in the natural killer cell function after the treatment. There were one complete response and one partial response. It could be speculated that LAK, Interleukin-2 and Cyclophosphamide therapy can be used as an adjuvant treatment for the advanced cancer.