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兪漢鐵,金聖勳,金東熙 대한본초학회 2001 大韓本草學會誌 Vol.16 No.1
To evaluate the effectiveness of Arctii Fructus(AF) in the treatment of allergy, studies were done experimentally. The results were obtained as follows : 1. Cytotoxicity of AF extract on the mouse lung fibroblast cells was not shown below the level of 100 ㎍/㎖ concentration. 2. In the quantification of IL-1β gene development, the amount was decreased compared to control group, gut which was insignificant. 3. Gene development of IL-4 was suppressed over 70% in the concentration of 100㎍/㎖ and also the of production of IL-4 was decreased significantly in the concentration of 100㎍/㎖ compared to the control group. 4. Gene development of Il-5 was decreased to 60% in the concentration of 100 ㎍/㎖ compared to the control group. 5. Gene development of IL-4 and IL-10 were decreased compared to the control group, but which was not significant. 6. Gene development of TNF-α was suppressed over 60% in the concentration of 10 ㎍/㎖ compared to the control group. 7. The effect of suppression of IgE production was significantly decreased in the concentration of 100㎍/㎖. 8. The effect of suppression of Histamine release was decreased significantly in the concentration of 100 ㎍/㎖. According to the above results, AF has antiallergic effects and suppression of the immune response. Thus it is suggested that aqua extract of AF could be applied to the aqua-acupuncture for suppressing humoral immune response, and further research is recommended.
유한철,金漢星 대전대학교 한의학연구소 2000 한의학연구소 논문집 Vol.9 No.1
From the reference research, the results obtained were as follows. 1.Until the "Song" dynasty, the predominant cause of faial nerve paralysis was the attack of Pathogenic Wind to "the Stomach Channel of Foot Yangming, (St.C.); and "the Small Intestine Channel of Hand Taiyang, (S.I.C.). They recognized the facial paralysis as an aspect of palsy. 2.In the period of Jin-Yuan(金元), the predominant cause was described as "Xuexu"(the deficiency of blood) and phlegm. They recognized that the facial palsy was a palsy. However, they also acceded to the possibility that there could be other explanations. 3.In the period of "Ming & Qing", there were numerous kinds of causes. For example, the following were identified as attacking the Meridian: the Pathogenic Cold; Pathogenic Heat; "Xinxu"(the deficiency in the heart); Fire and Heat combined as pathogenic factor; "Pixu"(the deficiency in the spleen); and, "Xinxu"(the deficiency of blood). 4.In the past, Koreans have explained the facial paralysis according to the Chinese theories mentioned. However, recently there has been an emergence of another Chinese theory; whereby, facial paralysis is classified into causes and symptoms, and then treatment is applied accordingly. 5.From the occident medical perspective, the facial paralysis is categorized into two causes. The first is called central facial nerve paralysis and the second is called peripheral facial nerve paralysis. The latter is mainly caused by Bell's palsy, Herpez zoster oticus, and trauma.