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      • KCI등재

        Is There Any Association Between Childhood Traumatic Experiences, Dissociation and Psychotic Symptoms in Schziophrenic Patients?

        Zeynep Yildiz Akbey,Mustafa Yildiz,Nermin Gü,ndü,z 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.5

        Objective: The aim of this study was to investigate the rates childhood traumatic experiences (CTEs) of schizophrenia patients and to examine relationship between childhood traumatic experiences, dissociation and psychotic symptoms. Methods: One hundred schizophrenia patients who had 5 or 5 points below in Clinical Global Impression-Severity (CGI-S) and who were not in active psychotic episode and 50 healthy siblings who grew up in the same environment with the patients were included to the study. Structured Clinical Interview for DSM IV, Scale for the Assessment of Positive Symptoms, Scale for the Assessment of Negative Symptoms, Dissociative Experiences Scale (DES), CGI-S, Global Assessment of Functioning Scale and Childhood Trauma Questionnaire (CTQ-28) applied to the patients. Results: Childhood abuse subscales and DES scores were statistically higher in the patient group (p<0.001). We determined moderately significant positive correlation between CTQ-28 and DES. We determined moderately significant positive correlation between CTQ total scores and persecutory delusions, delusions of reference, ability to feel intimacy and closeness; relationship with friends and peers. Also, there was a significant positive correlation between persecutory delusions and CTQ-total, DES-total and all subscales of CTQ-28. Conclusion: Clinicians should inquire about CTEs to develop comprehensive formulations and treatment plans among schizophrenia.

      • SCIESCOPUSKCI등재

        Physiological Profile of Growing Rats: Effects of Cage Type and Cage Density

        Yildiz, A.,Hayirli, A.,Okumus, Z.,Kaynar, O.,Kisa, F. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.2

        This experiment was conducted to examine the effects of cage type (CT) and cage density (CD) on physiological variables in growing rats. Sprague Dawley rats (n=108) weighing an average of 46 g were housed in metallic cage with woodchip bedding (MCWB), metallic cage with wire mesh (MCWM), and plastic shoebox with woodchip bedding (PCWB) separately by sex at normal ($160-cm^2/rat$, ND) and high ($80-cm^2/rat$, HD) CD from 3 to 10 wks of age. All cages were in dimension of $24{\times}40{\times}20$ cm ($W{\times}D{\times}H$). At the end of the experiment, blood samples were collected and 6 rats from each cage were sacrificed. No death was observed among rats at ND, whereas mortality rate at HD was 22.3% for males and 13.9% for females. Heart weight was affected by CT. Doubling CD caused 23, 11.8, 17.9, 8.6, 6.9, and 16.4% decreases in BW and weights of heart, liver, kidney, testis, and ovary, respectively. Except for adrenal gland, other organs for males were heavier than for females. Liver weight of males and females responded differently to CT and CD. Comparing with females, males had 7.3 and 5.2% heavier and 9.9% lighter liver weights in MCWB, MCWM, and PCWB, respectively. As CD doubled, liver weight for males and females decreased by 22.4 and 13.1%, respectively. Mean adrenal gland weight increased by 8.4% and decreased by 9.7% for males and females, respectively, with doubling CD. CT affected glucose, TG, Ca, and ALP levels. However, CD did not alter blood chemistry. Rats housed in metallic cages had greater neutrophil count and neutrophil:lymphocyte ratio than rats housed in plastic cages. Doubling CD caused a 24.2% increase in lymphocyte count. There were CT by CD, CT by sex, and CD by sex interaction effects on lymphocyte count. Doubling CD caused 0.1% decrease and 49.8 and 26.7% increases in lymphocyte count for rats housed in MCWB, MCWM, and PCWB, respectively. Comparing with females, lymphocyte count for males housed in MCWB, MCWM, and PCWB had 8.9 and 12.9% greater and 30.3% less lymphocyte counts, respectively. Lymphocyte count decreased by 4.12% for males, whereas it increased by 61.0% for females as CD doubled. Doubling CD resulted in 2.5 and 2.3% increases in erythrocyte count and hematocrit value. These data suggest that animals perform better in metallic cages than in plastic cages and that cage density had pronounceable effects on physiological parameters in a cage type and sex dependent-manner.

      • KCI등재

        Primary Effusion Lymphoma: An Untrivial Differential Diagnosis for Ascites

        Funda Ceran,Yusuf AydIn,Levent Özçakar,Ünsal Han,Mehmet YIldIz 연세대학교의과대학 2009 Yonsei medical journal Vol.50 No.6

        A primary effusion lymphoma is a rare type of non-Hodgkin’s lymphoma where serous cavities are involved. Thatcause peritoneal, pleural and pericardial effusions without any lymphadenopathy. They affect immunosuppressive patients with human herpes virus-8 being the suspected etiological agent. The prognosis is usually poor despite treatment. Herein, the case of an immunocompetent patient with ascites and pleural effusion diagnosed as primary effusion lymphoma is presented and discuss the case in the light of the current literature. A primary effusion lymphoma is a rare type of non-Hodgkin’s lymphoma where serous cavities are involved. Thatcause peritoneal, pleural and pericardial effusions without any lymphadenopathy. They affect immunosuppressive patients with human herpes virus-8 being the suspected etiological agent. The prognosis is usually poor despite treatment. Herein, the case of an immunocompetent patient with ascites and pleural effusion diagnosed as primary effusion lymphoma is presented and discuss the case in the light of the current literature.

      • SCIESCOPUSKCI등재
      • SCIESCOPUSKCI등재

        Experimental study on the rheology of anisotropic, flocculated and low volume fraction colloids

        Ozel, Burcu Genc,Orum, Aslihan,Yildiz, Mehmet,Menceloglu, Yusuf Z. 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.1

        In this work, we have investigated rheological behavior of colloids with a low particle volume fraction, and anisotropic and flocculated microstructures through measuring their viscosity and electrical resistance under varying shear rates together with utilizing several relevant characterization methods (i.e., Dynamic Light Scattering, Transmission Electron Microscopy, Atomic Force Microscopy, and Capacitance and Electrical resistance measurements). The colloids are formed through the suspension of hydrophilic/phobic fumed silica particle with attractive/repulsive interaction in polyethylene glycol and/or ethylene oxide-propylene oxide copolymer. It is observed that studied suspensions display shear thickening/thinning flow behavior depending on their microstructure (the spatial distribution and arrangements of particles in continuous media) and associated changes in cluster sizes, which are controlled by the break down of densified clusters (due to the shear induced mechanical and hydrodynamical forces) and the interaction forces among particle-particle and particles-polymers (owing to physicochemical effects). The detailed evaluation of the experimental results indicates that the shear thickening phenomena in low volume fraction, anisotropic and flocculated systems can be mainly attributed to the increase in the effective volume fraction of particles due to both hydrodynamic and physicochemical forces.

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