http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Sunyoung Cho(Sunyoung Cho),Heejo Koo(Heejo Koo),Beom Kyung Kim(Beom Kyung Kim),Euna Han(Euna Han) 대한약학회 2024 약학회지 Vol.68 No.1
Many studies have shown that statins reduce the risk of progression to liver cirrhosis (LC) and hepatocellular carcinoma (HCC) among at-risk populations. However, causality has not been proved. This study examined whether statins could prevent LC and HCC in patients with progressive and worsening chronic liver disease, using a robust methodology for causality. Between 2002 and 2013, 52,145 patients with chronic liver diseases were identified from the National Health Insurance Service database in South Korea. The inverse probability weighting (IPW) and superlearning targeted maximum likelihood estimation (TMLE) were used to assess the causality of statin use on the risk of LC and HCC, adjusting for sex, age, comorbidities, and co-medications. Multivariable superlearning TMLE revealed that statin use was associated with reduction in the incidence risk of LC (Marginal odds ratio (MOR) 0.59, 95% confidence interval [CI] 0.50-0.65) and HCC (MOR 0.59, 95% CI 0.50-0.67). Such a protective effect was more evident with atorvastatin and lipophilic statin. This population-based observational study indicated the benefit of statin use, particularly atorvastatin and lipophilic statin, for causally reducing the risk of LC and HCC.
What Drives the Customer Momentum?
Sunyoung Han 한국재무학회 2021 한국재무학회 학술대회 Vol.2021 No.11
This paper investigates possible explanations for the customer momentum documented by Cohen and Frazzini (2008). First, returns to the customer momentum vary significantly over time and can have large crashes during market crises. However, I do not find evidence linking the customer momentum to macroeconomic risk. Second, the customer momentum does not weaken significantly out-of-sample and thus is unlikely to be driven by statistical bias. Third, there is no evidence for the publication effect of Mclean and Pontiff (2016). Hence, the customer momentum does not represent profitable opportunities for arbitrage. Consistently, I show that the customer momentum is concentrated in stocks that are difficult to arbitrage. Moreover, trading on the customer momentum generates high turnovers but the probability of underperformance is not as high in annual frequency. Overall, my evidence suggests that limits-to-arbitrage prevent the incorporation of new information on customer firms into the share prices of suppliers.
Han, Sunyoung,Choi, Kyungho,Kim, Jungkon,Ji, Kyunghee,Kim, Sunmi,Ahn, Byeongwoo,Yun, Junheon,Choi, Kyunghee,Khim, Jong Seong,Zhang, Xiaowei,Giesy, John P. Elsevier 2010 Aquatic toxicology Vol.98 No.3
<P><B>Abstract</B></P> <P>Despite frequent detection of ibuprofen in aquatic environments, the hazards associated with long-term exposure to ibuprofen have seldom been investigated. Ibuprofen is suspected of influencing sex steroid hormones through steroidogenic pathways in both vertebrates and invertebrates. In this study, the effect of ibuprofen on sex hormone balance and the associated mechanisms was investigated <I>in vitro</I> by use of H295R cells. We also conducted chronic toxicity tests using freshwater fish, <I>Oryzias latipes</I>, and two freshwater cladocerans, <I>Daphnia magna</I> and <I>Moina macrocopa</I>, for up to 144 and 21d of exposure, respectively. Ibuprofen exposure increased 17β-estradiol (E2) production and aromatase activity in H295R cells. Testosterone (T) production decreased in a dose-dependent manner. For <I>D. magna</I>, the 48h immobilization EC50 was 51.4mg/L and the 21d reproduction NOEC was <1.23mg/L; for <I>M. macrocopa</I>, the 48h immobilization EC50 was 72.6mg/L and the 7d reproduction NOEC was 25mg/L. For <I>O. latipes</I>, 120d survival NOEC was 0.0001mg/L. In addition, ibuprofen affected several endpoints related to reproduction of the fish, including induction of vitellogenin in male fish, fewer broods per pair, and more eggs per brood. Parental exposure to as low as 0.0001mg/L ibuprofen delayed hatching of eggs even when they were transferred to and cultured in clean water. Delayed hatching is environmentally relevant because this may increase the risk of being predated. For <I>O. latipes</I>, the acute-to-chronic ratio of ibuprofen was estimated to be greater than 1000. Overall, relatively high acute-to-chronic ratio and observation of reproduction damage in medaka fish at environmentally relevant ranges of ibuprofen warrant the need for further studies to elucidate potential ecological consequences of ibuprofen contamination in the aquatic environment.</P>
The Textbook Analysis on Probability: The Case of Korea, Malaysia and U.S. Textbooks
( Han Sunyoung ),( Rosli Roslinda ),( Capraro Robert M. ),( Capraro Mary M. ) 한국수학교육학회 2011 수학교육연구 Vol.15 No.2
"Statistical literacy" is important to be an effective citizen ([Gal, I. (2005). Towards "probability literacy" for all citizens: Building blocks and instructional dilemmas. In: G. A. Jones (Ed.), Exploring probability in school: Challenges for teaching and learning (pp. 39-63). New York: Springer]). Probability and statistics has been connected with real context and can be used to stimulate students` creative abilities. This study aims at identifying the extent that textbooks in three countries include experimental probability concepts and non-routine, open-ended, application and contextual problems. How well textbooks reflect real application situations is important in the sense that students can employ probability concepts when solving real world problems. Results showed that three textbook series did not mention experimental probability. Furthermore, all of textbooks had more routine, close-ended, knowing, and non-contextual problems.
Design and Implementation of Virtual Terminal Protocol with Windowing Capability
Han, Sunyoung 건국대학교 1988 學術誌 Vol.32 No.2
컴퓨터 네트워크 환경에서는 서로 다른 특성을 갖는 호스트 컴퓨터가 존재할 뿐 아니라 서로 다른 특성을 갖는 터미날도 존재한다. 네트워크 상에 있는 터미날은 이기종 복수개의 호스트 컴퓨터에 접근할 수 있어야 하며, 호스트 컴퓨터에 있는 응용 프로그램도 네트워크 상에 있는 여러 형태의 터미날에서 사용될 수 있어야 한다. 만약 네트워크 상에 M 종류의 호스트와 N종류의 터미날이 존재한다면 어떤 응용프로그램이 네트워크 상에서 작동하기 위해서는 M×N 종류의 프로그램이 필요하다. 가상터미날은 실재하는 각종 터미날의 기능을 일반화시키고 추상화시켜 정의한 개념적으로 존재하는 표준터미날이다. 원격지 호스트에 있는 응용 프로그램과 로칼 호스트에 있는 터미날 사용자는 서로 가상터미날을 이용하여 통신하고 응용 프로그램은 가상터미날만을 제어하고 가상터미날과 로칼 호스트에 있는 실제 터미날 사이의 매핑은 로칼 호스트가 담당함으로써 M×N 문제가 M+N 문제로 축소된다. 본 논문에서는, 현재 국제 표준화기구(ISO)에서 정의하고 있는 가상터미날 모델에 기초하여 윈도우 기능을 갖는 가상터미날 프로토콜을 설계하고 구현하였다. 윈도우 기능은 bitmap 기 능을 제공하는 고급 터미날이나 워크스테이션 등에서 볼 수 있는 기능으로서, 윈도우 기능을 갖는 터미날은 일반적으로 문자 처리 능력뿐 아니라 그레픽스 및 이미지 처리 능력을 갖고 있다. 본 논문에서는 원격지 호스트에 있는 윈도우 시스템 등의 윈도우 기능을 갖는 소프트웨어를 로칼 호스트에 있는 Bitmap 터미날이나 Workstation등에서 사용할 수 있도록 가상터미날을 설계하고 구현하였다. 본 논문에서 연구한 가상터미날은 4.2BSD UNIX에서 C언어로 구현되었다.