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      • 상용차 기반에 대한 주차보조시스템 사용자 감성 평가

        전재석(Jaeseok Jeon),박현배(Hyunbae Park),문희석(Heeseok Moon),곽수진(Sujin Kwag) 한국자동차공학회 2013 한국자동차공학회 부문종합 학술대회 Vol.2013 No.5

        In this paper, we described about evaluation of human sensibility using park assist system of the commercial vehicle. The perpendicular parking and parallel parking have been carried out as a user test and subjects are classified as beginning drivers, drivers with less than 1 year experience and over 3 years experience. As a result, parking duration of beginning drivers and drivers with less than 1 year experience who use automatic parking assistance system is similar to drivers with over 3 years experience. However error occurred according to sensor position and distance between vehicle and parking space. And also it occurred that the vehicle leaves from parking line or does not recognize the parking space. Therefore, if we improve its completeness by compensating problems that came up from this evaluation and distribute the automatic parking assistance system, it is expected that the park assistance system is to help driver providing convenience of parking.

      • KCI우수등재

        도시녹지 유형에 따른 휘발성유기화합물 농도 특성

        조예슬(Yeseul Jo),박수진(Sujin Park),노관평(Gwan Pyeong Roh) 한국환경보건학회 2018 한국환경보건학회지 Vol.44 No.4

        Objectives: The occurrence characteristics of BTEXS and phytoncides were investigated by type of urban forest. Methods: Four types of urban green space (Hongneung Forest, Mt. Chunjang, residential park, and traffic island) and Gwangneung Forest were selected. Monitoring of phytoncides and BTEXS was conducted considering the activity times of urban residents (five times per day) using a Tenax TA tube and suction pump in June 2017 (one day). Results: Phytoncide concentrations were ranked as Gwangneung Forest>Hongneung Forest>Mt. Cheonjang> traffic island>residential park. Relatively high concentrations of phytoncides were also identified in the urban forest. There was no significant difference between Gwangneung Forest and the urban forest. BTEXS concentrations were ranked as traffic island>residential park>Hongneung Forest>Gwangneung Forest>Mt. Cheonjang. Traffic island and residential park showed high levels of BTEXS depending on the inflow of vehicles. The difference in concentration by time was significant for the traffic island in particular. Pollutant levels in Hongneung Forest were as low as in Gwangneung Forest. Conclusion: The concentrations of phytoncides and BTEXS were different by types of urban green space, and the potential for health and hygiene of urban forests were able to be investigated. This study is expected to provide as basic data for the creation of urban forest spaces in the future.

      • KCI등재

        Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation

        Park, Sujin,Yang, Kyung-Min,Park, Yuna,Hong, Eunji,Hong, Chang Pyo,Park, Jinah,Pang, Kyoungwha,Lee, Jihee,Park, Bora,Lee, Siyoung,An, Haein,Kwak, Mi-Kyung,Kim, Junil,Kang, Jin Muk,Kim, Pyunggang,Xiao, Korean Society of Cancer Prevention 2018 Journal of cancer prevention Vol.23 No.1

        <P><B>Background</B></P><P>Smad3 linker phosphorylation plays essential roles in tumor progression and metastasis. We have previously reported that the mutation of Smad3 linker phosphorylation sites (Smad3-Erk/Pro-directed kinase site mutant constructs [EPSM]) markedly reduced the tumor progression while increasing the lung metastasis in breast cancer.</P><P><B>Methods</B></P><P>We performed high-throughput RNA-Sequencing of the human prostate cancer cell lines infected with adenoviral Smad3-EPSM to identify the genes regulated by Smad3-EPSM.</P><P><B>Results</B></P><P>In this study, we identified genes which are differentially regulated in the presence of Smad3-EPSM. We first confirmed that Smad3-EPSM strongly enhanced a capability of cell motility and invasiveness as well as the expression of epithelial-mesenchymal transition marker genes, <I>CDH2</I>, <I>SNAI1</I>, and <I>ZEB1</I> in response to TGF-β1 in human pancreatic and prostate cancer cell lines. We identified <I>GADD45B</I>, <I>CTGF</I>, and <I>JUNB</I> genes in the expression profiles associated with cell motility and invasiveness induced by the Smad3-EPSM.</P><P><B>Conclusions</B></P><P>These results suggested that inhibition of Smad3 linker phosphorylation may enhance cell motility and invasiveness by inducing expression of <I>GADD45B</I>, <I>CTGF</I>, and <I>JUNB</I> genes in various cancers.</P>

      • Arctic Primary Aerosol Production Strongly Influenced by Riverine Organic Matter

        Park, Jiyeon,Dall’Osto, Manuel,Park, Kihong,Kim, Jung-Hyun,Park, Jongkwan,Park, Ki-Tae,Hwang, Chung Yeon,Jang, Gwang Il,Gim, Yeontae,Kang, Sujin,Park, Sanghun,Jin, Yong Keun,Yum, Seong Soo,Simó American Chemical Society 2019 Environmental science & technology Vol.53 No.15

        <P>The sources of primary and secondary aerosols in the Arctic are still poorly known. A number of surface seawater samples-with varying degrees of Arctic riverine and sea ice influences-were used in a sea spray generation chamber to test them for their potential to produce sea spray aerosols (SSA) and cloud condensation nuclei (CCN). Our interdisciplinary data showed that both sea salt and organic matter (OM) significantly influenced the SSA production. The number concentration of SSA in the coastal samples was negatively correlated with salinity and positively correlated with a number of OM tracers, including dissolved and chromophoric organic carbon (DOC, CDOM), marine microgels and chlorophyll <I>a</I> (Chl-<I>a</I>) but not for viral and bacterial abundances; indicating that OM of riverine origin enhances primary aerosol production. When all samples were considered, transparent exopolymer particles (TEP) were found to be the best indicator correlating positively with the ratio number concentration of SSA/salinity. CCN efficiency was not observed to differ between the SSA from the various samples, despite differences in organic characteristics. It is suggested that the large amount of freshwater from river runoff have a substantial impact on primary aerosols production mechanisms, possibly affecting the cloud radiative forcing.</P> [FIG OMISSION]</BR>

      • A study on the Similarity and Results of Opinion polls for Reviews by Online Media through Sentiment Analysis

        Suyeon Sun,Jenny Park,Baek Sujin,Haejin Chung,Jung Bokmoon,Park Sohyun,Seunghun Baek,Eung-Kyo Suh 한국차세대컴퓨팅학회 2021 한국차세대컴퓨팅학회 학술대회 Vol.2021 No.11

        The main research topic of this study is how much ‘opinion mining’ of online comments on specific keywords reflects actual public opinion. In detail, we compared and analyzed how much the results of sentiment analysis for comments by platform reflect the actual opinion poll results. We analyzed the most mentioned keywords by platform and by parking in the comments classified as positive, and the most mentioned keywords by platform and by parking in the comments classified as negative. As a result of the study, it was found that the results of the polls were similarly reflected in the order of the Naver News model, Naver News + YouTube model, and YouTube model. In addition, it was possible to find out keywords with high interest by positive/negative public opinion through positive/negative word cloud analysis by parking and platform.

      • KCI등재

        A Construction Morphology Analysis of Old English Genuine and Pseudo Synthetic Nominal Compounds: Schema Unification and Motivation

        Sujin Park 한국영어학학회 2019 영어학연구 Vol.25 No.3

        The main goal of this study is twofold. The first goal is to provide a Construction Morphology (CxM) analysis of OE [N N] Synthetic Nominal Compounds ([N V SF/-Ø]N SNCs), which may exhibit two internal structures ([[N V]V SF]N vs. [N [V SF]N]N) similar to the SNCs in Present-day English (PDE). Within the theoretical framework of ‘Word-based’ CxM (Booij 2010, Booij and Audring 2018), this study claims that OE [N V SF/-Ø]N SNCs can be seen as constructions consisting of two schemas for [N V]V verbal compounds (VCs) and [V SF/-Ø]N deverbal nouns (DNs), and tha t the forma tion o f OE SNCs ca n be better understood by assuming that the two schemas can be unified into one abstract schema for OE SNCs ([[Ni Vj]Vk SF/-Ø]Nm ↔ [Entity/Action/Resultant with ARGUMENT relation to SEMk]m). The second goal is to propose that the four types of OE [[N V]V SF/-Ø]N SNCs classified in this study receive full motivation from the unified abstract schema for OE [[N V]V SF/-Ø]N SNCs, and that the four type SNCs receive partial and multiple motivation from the three schemas for DNs, VCs, and base verbs, with which the four type SNCs are paradigmatically and systematically connected. A CxM analysis of OE SNCs has two important advantages that the possibility of making a generalization of OE SNCs, and that the unnecessariness of determining one ‘correct’ internal structure between two plausible ones.

      • KCI등재

        Over-characterized Constructions of Double Prefixal Verbs in Old English

        ( Sujin Park ) 대한영어영문학회 2021 영어영문학연구 Vol.47 No.4

        This study aims to look closely into the over-characterized double prefixal verbs with eight Prefix2s (aweg-, eft-, fore-, forð/þ-, fram-, of-, ūp-, ūt-) and with two Prefix1s (ā-, ge-) in Old English (OE). It is observed that semantic pleonasm is displayed in the double prefixal verbs when one of the eight Prefix2s denoting ‘Direction’ or ‘Movement’ is attached to the single prefixal verbs with one of the two Prefix1s that already hold the (same) semantic feature of ‘Direction’ or ‘Movement’. The phenomenon of OE prefix pleonasm is shown in the descriptive analysis of OE double prefixation by Kim (2013), where he views that the prefixes at the right position are meaningless and semantically faded by grammaticalization, while the prefixes at the left position maintain their (lexical) meanings. From the perspective of Construction Morphology (CxM) (Booij 2010), this article suggests that the pleonastic OE double prefixal verbs can be seen as special constructions with the phenomenon of overcharacterization, and that these over-characterized double prefixal verbs can be accounted for (and assumed to be made) by the morphological operation of schema imposition or unification (Booij 2005, 2010; Booij & Audring 2018). Different from Kim (2013), the present study argues that both the Prefix2s and Prefix1s bear the lexical and grammatical meanings, of which the meanings of the Prefix2s are expressed twice in the unified constructions of the double prefixal verbs in OE. (Hankuk University of Foreign Studies)

      • Protein O-GlcNAcylation regulates developmental growth of Drosophila through the insulin-IGF signaling pathway

        Sujin Park,Yeon Jung Kim,Si-Hyoung Park,JuYuel Baek,KwanSoo Kim,Jürgen Roth,Jin Won Cho,Kwang-Min Choe 한국당과학회 2011 한국당과학회 학술대회 Vol.2011 No.1

        Modification of nuclear and cytosolic proteins by O-linked N-acetylglucosamine (O-GlcNAc) is ubiquitous in cells. The in vivo function of the protein O-GlcNAcylation, however, is not well understood. Here, we genetically manipulated the cellular O-GlcNAcylation level in Drosophila and found that it promotes developmental growth by enhancing insulin signaling. This alteration of growth is due to cell growth and apoptosis and not to cell proliferation, and is mediated, at least in part, through O-GlcNAcylation of Akt. These results indicate that O-GlcNAcylation is one of the crucial mechanisms involved in control of insulin signaling in normal Drosophila development.

      • ERADication of EDEM1 occurs by selective autophagy

        Sujin Park,Insook Jang,Jin Won Cho,Jürgen Roth 한국당과학회 2013 한국당과학회 학술대회 Vol.2013 No.1

        Misfolded and misassembled glycoproteins are retained in the endoplasmic reticulum (ER) where they are exposed to the protein folding machinery and protein quality control. The Unfolded Protein Response is activated in response to an accumulation of unfolded or misfolded proteins in the lumen of the ER. Eventually, misfolded and mis-assembled glycoproteins are targeted for degradation by a process called ER-associated protein degradation (ERAD). EDEM1 is an ERAD component that interacts with misfolded luminal glycoproteins and routes them for dislocation. This is followed by their ubiquitination and proteasomal degradation. Although EDEM1 was proposed to be a lectin–like protein and to react with Man8GlcNAc2 oligosaccharides of glycoproteins, still very little is known about the turnover and degradation mechanism of EDEM1 and how this relates to the fate of its substrates. Previously, we reported that EDEM1 exits the ER by a vesicular non-COPII-mediated mechanism and becomes rapidly degraded by basal autophagy. Here, we provide detailed insight into the mechanism by which EDEM1 becomes degraded. After its dislocation to the cytosol, EDEM1 is apparently making complexes with the selective autophagy receptors p62, NBR1 and Alfy. We observed co-distribution of EDEM1 and selective autophagy receptors by double and triple confocal laser scanning immunofluorescence. By quantifying the relationship of EDEM1 and the selective autophagy receptors as visualized by confocal laser scanning immunofluorescence and double immunogold electron microscopy, dramatical changes were observed in HepG2 cells. Following inhibition of autophagy by wortmannin, the number and size of cytoplasmic clusters composed of EDEM1 and the selective autophagy cargo receptors dramatically increased and this aggregate formation was independent of the activity of HDAC6. We observed that deglycosylation of EDEM1 occurred by the action of the cytosolic peptide N-glycanase since treatment with inhibitors resulted in a strong increase in the amount of glycosylated EDEM1. Inhibition of cytosolic peptide N-glycanase also inhibited wortmannin-induced aggregation of EDEM1 and its complex formation with p62. This indicates that deglycosylation of EDEM1 is a prerequisite for subsequent ubiquitination and interaction with selective autophagy receptors. This demonstrates that the ERAD component EDEM1 itself undergoes ERAD involving selective autophagy

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