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Hongmei Xu,Libin Wang,Jian Huang,YanQing Zhang,Feng Ma,Jianmin Wang,WenChun Xu,XueMei Zhang,YiBing Yin,KaiFeng Wu 한국미생물학회 2015 The journal of microbiology Vol.53 No.2
Pneumococcal asymptomatic colonization of the respiratory tracts is a major risk for invasive pneumococcal disease. We have previously shown that pneumococcal wall teichoic acid (WTA) was involved in pneumococcal infection of sepsis and adherence to epithelial and endothelial cells. In this study, we investigated the contribution of pneumococcal WTA to bacterial colonization and dissemination in murine models. The result showed that nasopharynx colonizing D39 bacterial cells have a distinct phenotype showing an increased exposure of teichoic acids relative to medium-grown bacteria. The WTA-deficient mutants were impaired in their colonization to the nasopharynx and lungs, and led to a mild inflammation in the lungs at 36 h post-inoculation. Pretreatment of the murine nares with WTA reduced the ability of wild type D39 bacteria to colonize the nasopharynx. In addition, the WTA-deficient strain was impaired in its ability to invade the blood and brain following intranasal administration. WTA-deficient D39 strain was reduced in C3 deposition but was more susceptible to the killing by the neutrophils as compared with its parent strain. Our results also demonstrated that the WTA enhanced pneumococcal colonization and dissemination independently of the host strains. These results indicate that WTA plays an important role in pneumococcal pathogenesis, both in colonization and dissemination processes.
Libin Ma,Yang Liu,Sheng-Quan Xu 한국응용곤충학회 2015 Journal of Asia-Pacific Entomology Vol.18 No.4
Vietacheta, a cricket genus found across northern and southern Vietnam, is a rare taxon lacking any additional species discovered after the genus was established. This genus possesses features found across many other genera. Its general appearance is the same as Itaropsis; genitalia ectoparamere is very similar to Phonarellus; inner tympanum is absent, and particularly, the metanotum is armed with several hairs. Now, we found the first species of Vietacheta in China. The new species, Vietacheta harpophylla sp. nov., is close to Vietacheta aquila Gorochov, 1992, but they are different in details of anal plate, epiphallus, and ectoparamere. A description and illustration of this new species, a revision of other Vietacheta, and a key to the genus are provided.
Haiyan Xu,Zimeng Shao,Zhijie Wang,Libin Cai,Zhen Li,Xinzheng Jiang 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.3
This paper intends to obtain a sub-level classification of fully weathered red sandstone rock mass during the Cretaceous period based on physical property indices. An automatic prediction system for mechanical properties of rock mass is also established in which the values of rock mass grade and mechanical properties can be returned when physical indices are given. In this study, water content, relative compaction, and fine content, which are relatively easy to measure on tunnel sites, are selected as physical property indices, while cohesion, internal friction angle, and compression modulus, which affect mechanical strength, are taken as mechanical indices. For the convenience of analysis, rock mass of different physical states is divided into 18 different combinations based on the results of lab tests and rock mass stability of each state is evaluated using a stability evaluation criterion we put forward. The numerical simulation of tunnel excavation is further carried out for determining the sub-level classification. A decision tree model is applied for further studying the relationship between physical and mechanical indices to ensure accurate prediction. The result shows that the prediction system works with high accuracy and can be used for engineering reference for fully weathered red sandstone rock mass.
Zhu Yifan,Xu Feng Xiang,Guan Yijie,Zou Zhen,Duan Libin,Du Zhanpeng,Ma Hongfeng 한국자동차공학회 2023 International journal of automotive technology Vol.24 No.5
As an alternative to the conventional concave hexagonal honeycomb structure (CHHS), a negative Poisson’s ratio honeycomb structure with power function curve (NHPC) was devised. The relationship between the power function exponent (PFE) and normalized power function coefficient (NPFC) of honeycomb structure and its equivalent Poisson’s ratio (EPR) was explored to identify the range of variables required for the negative Poisson’s ratio effect. To investigate the in-plane mechanical properties and energy absorption characteristics of NHPC, the deformation mode, dynamic response, and energy absorption characteristics under various impact velocities were studied by constructing an in-plane impact simulation model. The results showed that NHPC obviously exhibited a negative Poisson’s ratio effect on medium and low impact velocities, and the deformation was primarily uniform. As the NPFC increased, the honeycomb structure was less prone to stress concentration, while the peak crushing force (PCF) and the specific energy absorption (SEA) declined and the plateau stress increased. A multi-objective optimization experiment was operated with low PCF and high SEA as the targets within the range of design variables in order to generate the optimal NHPC. According to the experimental findings, the improved NHPC showed a 25.48 % reduction in PCF and a 19.29 % increase in SEA. This paper provides theoretical recommendations for improving the energy absorption and structural optimization of the honeycomb structure.
Li Pan,Tao Gao,Fang Xu,Libin Zhang 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.2
Industrial assembly robots are designed to enable accurate and repeatable tracking of the positions and orientations of the robot’s end-effector and are hence often required to perform complex tasks within uncertain environments. Therefore, trajectory tracking control is vital to the wide range of applications of industrial robotic systems. This paper presents an enhanced robust motion tracking controller with disturbance adaption for trajectory tracking control of industrial assembly robot. The dynamics of the industrial assembly robotic system is formulated in the working space of the end-effector and the tracking control problem is then formulated. The enhanced robust motion tracking control is synthesized by using disturbance adaption and modified iterative control terms, which is a refined version of conventional robust adaptive control with only disturbance rejection. The capability and effectiveness of the enhanced robust motion tracking control have been evaluated based on an industrial robotic platform. The comparative results clearly show that the proposed control can be used to better minimize the trajectory tracking errors in finite time as compared with conventional proportional derivative control.
( Pingping Huang ),( Wen Su ),( Rui Han ),( Hao Lin ),( Jing Yang ),( Libin Xu ),( Lei Ma ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.4
In this study we aimed to develop novel ZnO-NP/chitosan/β-glycerophosphate (ZnO-NP/CS/β-GP) antibacterial hydrogels for biomedical applications. According to the mass fraction ratio of ZnO-NPs to chitosan, mixtures of 1, 3, and 5% ZnO-NPs/CS/β-GP were prepared. Using the test-tube inversion method, scanning electron microscopy and Fourier-transform infrared spectroscopy, the influence of ZnO-NPs on gelation time, chemical composition, and cross-sectional microstructures were evaluated. Adding ZnO-NPs significantly improved the hydrogel's antibacterial activity as determined by bacteriostatic zone and colony counting. The hydrogel's bacteriostatic mechanism was investigated using live/dead fluorescent staining and scanning electron microscopy. In addition, crystal violet staining and MTT assay demonstrated that ZnO-NPs/CS/β-GP exhibited good antibacterial activity in inhibiting the formation of biofilms and eradicating existing biofilms. CCK-8 and live/dead cell staining methods revealed that the cell viability of gingival fibroblasts (L929) cocultured with hydrogel in each group was above 90% after 24, 48, and 72 h. These results suggest that ZnO-NPs improve the temperature sensitivity and bacteriostatic performance of chitosan/β-glycerophosphate (CS/β-GP), which could be injected into the periodontal pocket in solution form and quickly transformed into hydrogel adhesion on the gingiva, allowing for a straightforward and convenient procedure. In conclusion, ZnO-NP/CS/β-GP thermosensitive hydrogels could be expected to be utilized as adjuvant drugs for clinical prevention and treatment of peri-implant inflammation.