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嚴柱澤,柳春桃,崔粉龍 고려대학교 의과대학 1972 고려대 의대 잡지 Vol.9 No.2
Concerning the histological structure of stomach in the bird, Mo¨llendorff's regard to proventricle and gizzard was generally accepted. Authors were interested in their mitotic behavior, and studied with fowls and domestic duck's gastric mucosa. Bouin fixation and Hall's(1970) triple stain-basic fuchsin and picro-indigo carmine were performed. Mitotic index, the frequency and distribution of mitotic cells in the various glands were observed with following results: 1. The mitotic indices for the proventricle and gizzard in fowls and ducks were highest in the gland of central sinus (compound gland), moderate in the surface gland of proventricle, and lowest in the gland of gizzard. 2. Mitotic figures were most frequently seen in the isthmus of glandular epithelium in the surface gland of proventricle, in the side wall of the gland of central sinus, and in the wall of the gizzard gland. However, mitotic figures were also scatteredly observed at the bottom and in the upper portion of the gland.
Molecular discrimination of Panax ginseng species
Um, Jae-Young,Chung, Hwan-Suck,Kim, Hyun-Ju,Kim, Dae-Ki,Shim, Kyung-Shik,Lee, Kang-Yong,Kim, Jeong-Sook,Choi, Tae-Jin,Kim, Nam-Song,An, Nyeon-Hyoung,Lee, Kang-Min,Lee, Young-Mi,Kim, Jeong-Joong Kyung Hee Oriental Medicine Research Center 2000 International journal of oriental medicine Vol.1 No.2
In order to develop convenient and reproducible methods for identification of ginseng drugs at a DNA level, RAPD (randomly amplified polymorphic DNA) and PCR-RFLP (PCR-Restriction fragment length polymorphism) analysis were applied within Panax species. To authenticate Panax ginseng betvyeen Chinese and Korean ginseng population, RAPD analysis were carried out using 20 mer-random primer. The similarity coefficients among the DNA of ginseng plants analyzed were low, ranging from 0.197 to 0.491. In addition, using PCR-RFLP analysis, very different fingerprints were obtained within Korean ginseng plants. These results suggest that these methods are able to authenticate the concerned Panax species. Broader application of this approach to authenticate other morphologically similar medicinal materials is rationalized.
( Yong Dae Kwon ),( Hoon Jai Chun ),( Soon Ho Um ),( Chang Duck Kim ),( Ho Sang Ryu ),( Yoon Tae Jeen ),( Jin Su Jang ),( Ju Young Kim ),( Chul Young Kim ),( Sang Hoon Park ),( Bora Keum ),( Yeon Seok 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: Screening guideline for colorectal cancer in average-risk asymptomatic population recommends colonoscopy starting at age 50. One prior study has reported the prevalence and low cost-effectiveness of colorectal neoplasia with colonoseopic screening in asymptomatic population aged 40-49 (Imperale et al.). However, recently colonoscopic detection rate of colorectal cancer of young age (<50) is increasing. Therefore, we investigated the prevalence of advanced neoplasia with colonoscopy according to age and evaluated the optimal age of screening colonoscopy. Methods: We reviewed the medical records of average-risk asymptomatic 1.745 persons performed screening colonoscopy from January 2001 to December 2006 in Korea university medical center. High risk patients (family history of cancer, IBD, previous history of adenoma) were excluded. Advanced neoplasia was defined as tubular adenoma measuring 1 cm or larger, any villous histology, high grade dysplasia, or cancer. Results: Overall prevalence of colorectal adenoma was 38.9% (679 of 1,744) and prevalence of advanced adenoma was 2.06% (36 of 1.744). Of the 489 persons in the 40-49 age group, 127 (25.97%) had one or more adenomas, and 6 (1.23%) had an advanced neoplasia, 2 (0.41%) had cancer. Of the 633 persons in the 50-59 age group, 270 (42.65%) had one or more adenomas, and 9 (1.42%) had an advanced neoplasia, 3 (0.47%) had cancer. Conclusions: The prevalence of advanced neoplasia in 40-49 and 50-59 age groups was lower than previous study. However, our study shows similar prevalence of advanced neoplasia between 40-49 and 50-59 age groups. Therefore, we should consider screening colonoscopy for early colorectal cancer earlier than 50 in average-risk asymptomatic population.