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Cho, Jung Sun,Youn, Ho-Joong,Her, Sung-Ho,Park, Maen Won,Kim, Chan Joon,Park, Gyung-Min,Jeong, Myung Ho,Cho, Jae Yeong,Ahn, Youngkeun,Kim, Kye Hun,Park, Jong Chun,Seung, Ki Bae,Cho, Myeong Chan,Kim, C The Korean Academy of Medical Sciences 2015 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.30 No.7
<P>The prognostic value of the left ventricle ejection fraction (LVEF) after acute myocardial infarction (AMI) has been questioned even though it is an accurate marker of left ventricle (LV) systolic dysfunction. This study aimed to examine the prognostic impact of LVEF in patients with AMI with or without high-grade mitral regurgitation (MR). A total of 15,097 patients with AMI who received echocardiography were registered in the Korean Acute Myocardial Infarction Registry (KAMIR) between January 2005 and July 2011. Patients with low-grade MR (grades 0-2) and high-grade MR (grades 3-4) were divided into the following two sub-groups according to LVEF: LVEF ≤ 40% (n = 2,422 and 197, respectively) and LVEF > 40% (n = 12,252 and 226, respectively). The primary endpoints were major adverse cardiac events (MACE), cardiac death, and all-cause death during the first year after registration. Independent predictors of mortality in the multivariate analysis in AMI patients with low-grade MR were age ≥ 75 yr, Killip class ≥ III, N-terminal pro-B-type natriuretic peptide > 4,000 pg/mL, high-sensitivity C-reactive protein ≥ 2.59 mg/L, LVEF ≤ 40%, estimated glomerular filtration rate (eGFR), and percutaneous coronary intervention (PCI). However, PCI was an independent predictor in AMI patients with high-grade MR. No differences in primary endpoints between AMI patients with high-grade MR (grades 3-4) and EF ≤ 40% or EF > 40% were noted. MR is a predictor of a poor outcome regardless of ejection fraction. LVEF is an inadequate method to evaluate contractile function of the ischemic heart in the face of significant MR.</P>
골시멘트비사용 Metal-bascked Cup에서 발생한 Polyethylene liner의 조기 역학적 실패
이중명 ( Joong Myung Lee ),조덕연 ( Duck Yun Cho ),박인섭 ( In Seop Park ),이중배 ( Joong Bae Lee ) 대한고관절학회 1993 Hip and Pelvis Vol.5 No.1
Successful total hip arthroplasty in its current form was made by Sir John Charnley. The incidence of acetabular loosening appears to increase at about 5-7 years after surgery. Over the last decade, a number of modifications in acetabular component design have been undertaken to solve this problem. In 1971, for purpose of reduction of peak stress occurring in cement and trabecular bone of the acetabulum, Harris reported a series of metal-backed acetabrlar components with removable polyethylene liners that could be replaced if excessive wear ocurred. Although long-term survivorship analysis has not demonstrated substantial improvement with the use of metal backing, most current acetabular designs retain the matal backing as a means of acetabular fixation. Even more, recent reports of porous-ingrowth of cementless cup have generally been favorable and few revision have been reported. The increasing use of cementless metal-backed acetabular components in total hip arthroplaty produced another mechanical interface that may fail: Mechanical failure of polyethylene liner in metal backed cup. We report two cases of early failure of polyethylene liner in cementless metal backed cup, and review previously reported articles.
젊은 대퇴골두 무혈성 괴사 환자에서 시행한 Cementless Spotorno(CLS) 스템을 사용한 인공 고관절의 5-9년 임상 추시결과
이중명 ( Joong Myung Lee ),조덕연 ( Duck Yun Cho ),황재광 ( Jae Kwang Hwang ),이중배 ( Joong Bae Lee ) 대한고관절학회 1996 Hip and Pelvis Vol.8 No.2
A retrospective follow-up study was perfomend with clinical and radiographic results of uncemented total hip arthroplasty using CLS(Cementless Spotorno, Protek, Berne, Switzerland) in 40 patients(53 hips) with osteonecrosis of the femoral head at the department of orthopaedic surgery, National Medical Center from November 1987 to November 1991. The average age at surgery was 45.5 years (range, 30-55 years). 15 Weill threaded cup, 19 expansion cup and 19 bipolar cup were used for the acetabular components. The Average Harris hip score improved from 49 to 96 points and revealed mild thigh pain in 2 hips (3.8%) and intermittent groin pain in 3 bipolar hips(5.7%). The radiographic evaluation demonstrated that significant reactive lines showed in 8 femoral components (15%) and in 4 acetabular components( I Weill cup, 3 expansion cup), endosteal bone formation in 42 hips (79%), cortical hypertrophy in 29 hips (55%) and calcar atrophy in 29 hips (55%), and also stem subsidence more than 4 mm, in 1 hip, heterotopic ossification, in 11 hips(21%). No revision was performed for aseptic loosening, failure, or infection.
Threaded Acetabular Cup은 과연 모두 문제가 있는가? -CLW threade cup의 5년 이상 추시 결과-
이중명 ( Joong Myung Lee ),조덕연 ( Duck Yun Cho ),나기호 ( Ki Ho Nah ),이중배 ( Joong Bae Lee ) 대한고관절학회 1995 Hip and Pelvis Vol.7 No.2
We reviewed 14 patients(22 hips) to whom had been performed total hip arthroplasty using CLW(CementLess weill, Protek, Switzerland)acetabular cup at the department of orthopaedic surgery, National Medical Center from February 1988 to August 1990. The purpose of this retrospective follow-up study was to analyze the radiological findings such as loosening or migration at the acetabular component and to assess the usefulness of the CLW cup. The CLW acetabular cup is made of self-tapping, double-threaded anchoring ring with deep pitch and low profile and it is made of pure titanium with rough corundum blasted surface. The average age of the patients at operation was 49 year(23-62 years) and all were male. The mean follow-up period was 6years and 3months(from Syears 2months to 7years 9months). The operation had been performed by a single surgeon(J-M Lee) using transgluteal approach. We analyzed the loosening and migration on the immediate postoperative and last follow-up plain X-ray film by Engh's criteria, which demonstrated no loosening and migration. While we need long term follow-up, we think that threaded cups which are well designed biomechanically and have good surface with bone on-growth capability should make different results compared to the poor results of other threaded cups.
Anthropometric Mismatch Investigation on Washing Machines for Wheelchair Users
Joong Hee Lee,NamWoo Cho,Yoonki Kim,Hwan Lee,Sejin Song,Myung Hwan Yun 한국HCI학회 2020 한국HCI학회 학술대회 Vol.2020 No.2
More than 200 million people encounter significant difficulties in performing daily activities. Large portion of those people are disabled population due to spinal cord injuries, and, despite the high number, there has been inadequate amount of research using anthropometric measurements to provide accessible design for pursuing simple daily activities. The purpose of this research is to provide a design guideline on washing machine for the people on a wheelchair. This study observes the anthropometric dimensions of people on a wheelchair to identify accessible measurements for designing washing machine. Mismatch equation is used not only to discover the accommodation levels of selected washing machines in the market and to find out the design strategies of washing machines.
Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2
Cho, Yong Soon,Lee, Jae Il,Shin, Dongkyu,Kim, Hyun Tae,Cheon, Young Hoon,Seo, Chang Il,Kim, Yong Eun,Hyun, Young-Lan,Lee, Yoon Sup,Sugiyama, Kanako,Park, Sam-Yong,Ro, Seonggu,Cho, Joong Myung,Lee, Tae Wiley Subscription Services, Inc., A Wiley Company 2008 Proteins Vol.70 No.1