A 15-amino acid C-terminal peptide of beta-defensin-3 inhibits bone resorption by inhibiting the osteoclast differentiation and disrupting podosome belt formation

Park, Ok-Jin,Kim, Jiseon,Ahn, Ki Bum,Lee, Jue Yeon,Park, Yoon-Jeong,Kum, Kee-Yeon,Yun, Cheol-Heui,Han, Seung Hyun Springer-Verlag 2017 Journal of molecular medicine Vol.95 No.12

First Record of the Interstitial Annelid Pharyngocirrus uchidai (Annelida: Saccocirridae) from Korea, Confirmed by Topotypic DNA Barcoding Data from Japan

Park, Jiseon,Kajihara, Hiroshi,Jung, Jongwoo The Korean Society of Systematic Zoology 2019 Animal Systematics, Evolution and Diversity Vol.35 No.1

The marine interstitial annelid Pharyngocirrus uchidai(Sasaki, 1981) has been only known from Japan. In this study, we report the occurrence of P. uchidai for the first time in four localities along the eastern coast of Korea: Bukmyeon, Gamchu, Gase, and Oeongchi. Species identification was confirmed by comparison of DNA barcoding sequences with morphological examination from the type locality, Oshoro, Japan. We generated a total of 25 sequences of a partial segment (580 bp) of the cytochrome c oxidase subunit I gene (COI), representing five specimens from each locality. Maximum intra-specific variation was 1.2% in terms of Kimura two-parameter (K2P) distance, observed between two individuals each from Gamchu (i.e., between two specimens from the single locality), Gamchu and Oeongchi, Gamchu and Oshoro, and Oeongchi and Oshoro. On the other hand, an identical haplotype was found in all the five localities, substantiating our species identification for the Korean populations. Inter-specific K2P distance between P. uchidai and an unidentified Saccocirrus sp. from Canada (based on public database entries) was 22.4-23.4%.

Diagnostic Conundrum: Fever and Pyuria Preceding Diagnosis of Kawasaki Disease in Children

( Jiseon Park ),( Young June Choe ),( Seung Ah Choe ),( Jue Seong Lee ),( Hyung Eun Yim ),( Yun-kyung Kim ) 대한소아감염학회 2023 Pediatric Infection and Vaccine Vol.30 No.3

농뇨는 가와사키병 환아의 약 30-60%에 동반되는 소견으로, 임상적 증후가 다 나타나지 않은 초기의 가와사키병 또는 불완전 가와사키병에서 요로감염으로 오인할 수 있으나, 불완전 가와사키병 진단에 중요한 검사실 소견 중 하나일 수 있다. 본 연구에서는 한국의 5세 미만 영유아에서 가와사키병 진단 전 요로감염으로 선행 진단 사례의 유병률과 역학적 위험인자를 평가하고자 한다. 건강보험심사평가원에서 제공하고 있는 보건의료 빅데이터 개방시스템 자료를 바탕으로 2007년 11월부터 2019년 10월까지 가와사키병과 요로감염으로 진료, 청구된 대상자에 대해 후향적 단면연구를 시행하였다. 가와사키병 확정 진단 전 1주일 이내의 요로감염 선행 진단된 환아의 발생률을 계산하였고, 카이제곱 (χ2 test) 검정을 실시하였다. 연령, 성별, 지역, 계절별 발생률에 대한 요로감염 선행 진단 여부에 대해 로지스틱 분석 (logistic regression)을 수행하였다. 연구 결과, 총 53,822명의 가와사키병 환자가 포함되었으며 그 중 304명 (0.56%)이 선행요로감염 진단이 있었다. 12개월 미만에서의 요로감염 선행 진단률이 가장 높았으며 (0.95%), 4세와 비교했을 때 요로감염 선행진단의 오즈비는 3.12 (2.05-4.77) 였다. 발열을 동반한 농뇨가 있는 영아의 일부에서는 불완전 가와사키병의 감별진단이 필요할 수 있다 Purpose: Children with incomplete Kawasaki disease (KD) and pyuria may be misdiagnosed with urinary tract infection (UTI) during the early phase of the prodrome. We investigated the percentage of UTI diagnoses preceding a KD diagnosis. Methods: Using the National Health Insurance data of South Korea, we assessed differences in UTI diagnoses made during the week preceding a KD diagnosis, according to demographic and geographic factors from November 2007-October 2019. Results: A total of 53,822 KD cases were identified, including 304 patients (0.56%) diagnosed with a UTI during the week preceding a KD diagnosis. The younger age group (0-11 months) showed the highest percentage of preceding UTI diagnoses (0.95%), with higher odds than 4-year-old children (3.12; 95% confidence interval, 2.05-4.77). Conclusions: These findings suggest a potentially misleading presentation of incomplete KD, a clinical conundrum requiring further investigation and validation, particularly in infants

Negative Declarative Question-answer Sequences in English Conversation

Jiseon Park 한국응용언어학회 2009 응용 언어학 Vol.25 No.3

Using conversion analytic framework, this paper examines negative declarative yes/no question-answer sequences that are produced in naturally occurring English conversation. The analysis explicates various action that are implemented through a negative declarative question, such as doing an understanding check, providing a potential account, or registering and resolving an unexpectedness. The paper also illustrates the ways in which different responses are produced to different action embodied through a negative declarative question. The analysis demonstrates that a negative declarative question. The analysis demonstrates that a negative declarative yes/no question invokes different degrees of epistemic gradient between conversational speakers depending on the interactional contexts in which the question is embedded and the speakers use the declarative question-answer sequence as to achieve different interactional goals, even beyond the basic function of requesting the answerer to affirm the truth of the proposition.

Pre-verbal Negation Yes/No Question-Answer Sequences in Conversation

Jiseon Park 사단법인 한국언어학회 2009 언어학 Vol.0 No.55

Using conversation analytic framework, this paper explicates how sequential structures and action formations are organized through an adjacency pair of negative yes/no question with pre-verbal negation and its response in naturally occurring Korean conversations. The paper demonstrates that (ⅰ) the pre-verbal negation yes/no question can frame an understanding of a negative event (a negated propositional content) that the questioner "noticed" from the preceding talk and (ⅱ) speakers use the negative question to implement various actions, such as understanding check, information request, or complaint/accusation, depending on the sequential position of the question and what is being addressed as ‘negative’. The paper also examines the ways in which responses are produced to different actions embodied by pre-verbal negation yes/no questions. The analysis demonstrates that an utterance is understood by speakers for the action that the utterance implements, even beyond the constraints set by the form itself.

Understanding Requests in Children’s Play

Jiseon Park 한국영어어문교육학회 2015 영어어문교육 Vol.21 No.3

The present study is an attempt to understand requests in naturally occurring English conversation between two children by delineating how they organize their daily face-to-face interaction. In this study, requests are viewed as a communicative tool used with an aim to control other’s behavior. Using video data and adopting Goodwin’s (2002) systematic framework for the analysis of social action within situated activity, the study focuses on how children employ different kinds of semiotic resources in order to accomplish the course of action embedded within a situated activity, which is solving a puzzle together. From this analysis it is demonstrated that children deploy a number of different semiotic fields, such as talk, gesture and participation framework and that they use different forms (verbal or non-verbal) of requests and responses continuously reshaping the temporally available range of semiotic resources. The results of the study may shed a light on our understanding of requests and their responses produced by young native speakers of English in naturally occurring conversation, which will again help us conceptualize the uses of requests in the English learning situation, especially for young learners of English.

The Two Forms of English Negative Yes/No Question and Practices of Challenging in Conversation

Jiseon Park 담화·인지언어학회 2013 담화와 인지 Vol.20 No.2

This study uses the method of conversation analysis and explicates the ways in which the two alternative forms of negative yes/no question-declarative and interrogative-are used to implement the social action of challenge in naturally occurring conversation. The analysis shows that a negative declarative question can frame a challenge against what was conveyed in the preceding talk for its appropriateness or correctness. In this case, the negative declarative question addresses an epistemic conflict against general and/or cultural knowledge of how the world operates. This study also examines the challenging action implemented through a negative interrogative question. The analysis demonstrates that the strong assertiveness delivered through a negative interrogative is similar to that of a negative declarative but that the negation portion of the negative interrogative does not actually negate the propositional content of the question as the negative declarative question does. Instead, the negation of a negative interrogative is related to projecting a strong assertiveness of the speaker to the matter addressed through the question. Based on the findings of the analysis, the paper suggests that speakers treat the two question formats as different interactional objects that have different epistemic and interactional consequences.

Storytelling in Multi-party Face-to-Face Interaction

Jiseon Park 담화·인지언어학회 2010 담화와 인지 Vol.17 No.1

The study examines a specific kind of storytelling: a principal character of the story being told is present and actively participates in the activity. Using video data and giving attention to what the present principal character does in the interaction as well as the teller of the story, the paper demonstrates that a storytelling in multi-party face-to-face interaction is a public, multi-party, and embodied interactive field. The study also explicates the ways in which participants of storytelling in face-to-face interaction take up a stance to the story and to other interlocutors as the story unfolds. The findings of the study suggest that stance should be understood as a social, public and interactional concept. The study emphasizes that the nature of storytelling in social interaction can be properly understood by describing how individual participants construct the telling of story in concert with one another and consequentially achieve their public existence.

스마트팜 내 신재생에너지 최적화 도입을 위한 해석적 연구

박지선(Jiseon Park),양원(Won Yang),이용운(Yongwoon Lee),홍종섭(Jongsup Hong),김희곤(Heegon Kim),정수호(Sooho Jung),윤가윤(Gayun Yun),정종모(Jongmo Jung) 한국연소학회 2022 KOSCOSYMPOSIUM논문집 Vol.2022 No.5

항공레저스포츠산업 환경 분석 및 발전전략 탐색

박지선(Park Jiseon),서호정(Seo Hojeong),원형중(Won Hyungjoong) 한국콘텐츠학회 2012 한국콘텐츠학회 종합학술대회 논문집 Vol.2012 No.5