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      • KCI등재

        Demotivating factors in learning English for elementary school students

        Lee,Jihye,Lee,Chung-Hyun 한국초등영어교육학회 2011 초등영어교육 Vol.17 No.1

        This study aims to identify the demotivating factors in learning English for Korean 5th and 6th graders and determine the differences in the demotivating factors according to students’ gender and English proficiency. For this study, a 57-item questionnaire was constructed based on eight demotivating factors: teachers’ personality and teaching style, class environment, reduced motivation and interest, characteristics of class, difficulty of learning English, negative attitudes toward second language (L2), attitude of group members, and grading and test score. The questionnaire was completed by 170 students, and seven students were then interviewed. The first finding was that reduced motivation and interest, difficulty of learning English, and characteristics of class were the most demotivating factors in respective order. The second finding showed that male students tended to have more negative attitudes toward L2. The third finding was that the lower their proficiency levels were, the more the students attributed their demotivation to reduced motivation and interest, difficulty of learning English, negative attitudes toward L2, attitude of group members, and grading and test score factors. Based on the results, it is suggested that through identifying learners’ demotivating factors, teachers can reduce the causes of demotivation using various methods applicable for the respective demotivating factors.

      • KCI우수등재

        SSP 기후변화 시나리오에 따른 농업용 저수지 홍수조절능력 분석

        김지혜 ( Kim¸ Jihye ),곽지혜 ( Kwak¸ Jihye ),황순호 ( Hwang¸ Soonho ),전상민 ( Jun¸ Sang Min ),이성학 ( Lee¸ Sunghack ),이재남 ( Lee¸ Jae Nam ),강문성 ( Kang¸ Moon Seong ) 한국농공학회 2021 한국농공학회논문집 Vol.63 No.5

        The objective of this study was to evaluate the flood control capacity of the agricultural reservoir based on state-of-the-art climate change scenario - SSP (Shared Socioeconomic Pathways). 18 agricultural reservoirs were selected as the study sites, and future rainfall data based on SSP scenario provided by CMIP6 (Coupled Model Intercomparison Project 6) was applied to analyze the impact of climate change. The frequency analysis module, the rainfallrunoff module, the reservoir operation module, and their linkage system were built and applied to simulate probable rainfall, maximum inflow, maximum outflow, and maximum water level of the reservoirs. And the maximum values were compared with the design values, such as design flood of reservoirs, design flood of direct downstream, and top of dam elevation, respectively. According to whether or not the maximum values exceed each design value, cases were divided into eight categories; I-O-H, I-O, I-H, I, O-H, O, H, X. Probable rainfall (200-yr frequency, 12-h duration) for observed data (1973∼2020) was a maximum of 445.2 mm and increased to 619.1∼1,359.7 mm in the future (2011∼2100). For the present, 61.1% of the reservoirs corresponded to I-O, which means the reservoirs have sufficient capacity to discharge large inflow; however, there is a risk of overflowing downstream due to excessive outflow. For the future, six reservoirs (Idong, Baekgok, Yedang, Tapjung, Naju, Jangsung) were changed from I-O to I-O-H, which means inflow increases beyond the discharge capacity due to climate change, and there is a risk of collapse due to dam overflow.

      • KCI등재후보

        Overseas Digital Citizenship Education Research Analysis and Implications

        JiHye Lee(JiHye Lee) 한국아세아태평양교육문화융복합학회 2022 Asia Pacific Journal of Teaching and Learning Vol.2 No.2

        Purpose The purpose of this study is to examine digital citizenship education in other countries and to suggest future directions for digital citizenship education. Through this, it is intended to provide implications for curriculum revision and subjects related to digital citizenship. Method In order to achieve the purpose of this study, websites, papers, and books were analyzed. In the EU, digital citizenship education presented by the Council of Europe was examined. In the UK, I analyzed the Connected World of the UK Council for Internet Safety. In Australia, I looked at two institutions: the New South Wales Department of Education and the ARC Centre of Excellence for the Digital Child. Common Sense, a nonprofit organization in the US, Smart Media that is a center for digital and media literacy in Canada, and DQ Institute in Singapore were also analyzed. Results Based on the examination of digital citizenship education in other countries, it was found that they emphasize responsibility within the digital society by paying attention to the connectivity of the digital society. For safety in the digital society, education in understanding the digital society and its characteristics is proposed. In addition, the rights within the digital society are considered important in protecting the digital rights of the self and others. Conclusion Since digital use is not limited to schools, education connected with home and society is necessary. For this, digital citizenship education for parents is needed. It is also necessary to recognize the importance of cultivating digital citizenship in society. In addition, it is necessary to develop a variety of educational material and educational programs that can be used in schools, homes, and organizations.

      • Dairy food consumption is associated with a lower risk of the metabolic syndrome and its components: a systematic review and meta-analysis

        Lee, Mijin,Lee, Hanna,Kim, Jihye Cambridge University Press 2018 The British journal of nutrition Vol.120 No.4

        <B>Abstract</B><P>A systematic review and a meta-analysis of observational studies were performed to assess the dose-response relationship between specific types of dairy foods and the risk of the metabolic syndrome (MetS) and its components. Studies of dairy foods and the risk of the MetS and its components published up to June 2016 were searched using PubMed, EMBASE and a reference search. Random-effects models were used to estimate the pooled relative risks (RR) with 95 % CI. Finally, ten cross-sectional studies, two nested case-control studies and twenty-nine cohort studies were included for the analysis. In a dose-response analysis of cohort studies and cross-sectional studies, the pooled RR of the MetS for a one-serving/d increment of total dairy food (nine studies) and milk (six studies) consumption (200 g/d) were 0·91 (95 % CI 0·85, 0·96) and 0·87 (95 % CI 0·79, 0·95), respectively. The pooled RR of the MetS for yogurt (three studies) consumption (100 g/d) was 0·82 (95 % CI 0·73, 0·91). Total dairy food consumption was associated with lower risk of MetS components, such as hyperglycaemia, elevated blood pressure, hypertriacylglycerolaemia and low HDL- cholesterol. A one-serving/d increment of milk was related to a 12 % lower risk of abdominal obesity, and a one-serving/d increment of yogurt was associated with a 16 % lower risk of hyperglycaemia. These associations were not significantly different by study design, study location or adjustment factors. This meta-analysis showed that specific types of dairy food consumption such as milk and yogurt as well as total dairy food consumption were inversely related to risk of the MetS and its components.</P>

      • One-Step Peptide Backbone Dissociations in Negative-Ion Free Radical Initiated Peptide Sequencing Mass Spectrometry

        Lee, Jihye,Park, Hyeyeon,Kwon, Hyuksu,Kwon, Gyemin,Jeon, Aeran,Kim, Hugh I.,Sung, Bong June,Moon, Bongjin,Oh, Han Bin American Chemical Society 2013 ANALYTICAL CHEMISTRY - Vol.85 No.15

        <P>Peptide dissociation behavior in TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl)-based FRIPS (free radical initiated peptide sequencing) mass spectrometry was analyzed in both positive- and negative-ion modes for a number of peptides including angiotensin II, kinetensin, glycoprotein IIb fragment (296–306), des-Pro<SUP>2</SUP>-bradykinin, and ubiquitin tryptic fragment (43–48). In the positive mode, the ·Bz-C(O)–peptide radical species was produced exclusively at the initial collisional activation of <I>o</I>-TEMPO-Bz-C(O)–peptides, and two consecutive applications of collisional activation were needed to observe peptide backbone fragments. In contrast, in the negative-ion mode, a single application of collisional activation to <I>o</I>-TEMPO-Bz-C(O)–peptides produced extensive peptide backbone fragmentations as well as ·Bz-C(O)–peptide radical species. This result indicates that the duty cycle in the TEMPO-based FRIPS mass spectrometry can be reduced by one-half in the negative-ion mode. In addition, the fragment ions observed in the negative-ion experiments were mainly of the <I>a</I>-, <I>c</I>-, <I>x</I>-, and <I>z</I>-types, indicating that radical-driven tandem mass spectrometry was mainly responsible for the TEMPO-based FRIPS even with a single application of collisional activation. Furthermore, the survival fraction analysis of <I>o</I>-TEMPO-Bz-C(O)–peptides was made as a function of the applied normalized collision energy (NCE). This helped us to better understand the differences in FRIPS behavior between the positive- and negative-ion modes in terms of dissociation energetics. The duty-cycle improvement made in the present study provides a cornerstone for future research aiming to achieve a single-step FRIPS in the positive-ion mode.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2013/ancham.2013.85.issue-15/ac303517h/production/images/medium/ac-2012-03517h_0010.gif'></P>

      • Marinopyrones A-D, α-pyrones from marine-derived actionmycetes of the family Nocardiopsaceae

        ( Jihye Lee ),( Chulkyeong Han ),( Tae Gu Lee ),( Jungwook Chin ),( Hyukjae Choi ),( Wonjae Lee ),( Man Jeong Paik ),( Dong Hwan Won ),( Gyusang Jeong ),( Jaeyoung Ko ),( Yeo Joon Yoon ),( Sang Jip Na 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-

        Two actinomycetes, a member of the rare halophilic genus Streptomonospora and a Nocardiopsis sp. (Nocardiopsaceae), strains CNQ-082 and CNQ-675, respectively. were isolated from marine sediments collected off shore near La Jolla. California. HPLC-UV guided fractionations of the extracts of these strains yielded marinopyrones A-D (1-4), the structures of which were elucidated by interpretation of 10 and 20 NMR and HRMS spectroscopic data. Oxidative ozonation, followed by conversion of the acid product to an α-naphthyl amide, provided the absolute configuration at the chiral center on the side-chain. Marinopyrones A-D were examined for the inhibitory activity on nitric oxide production in LPS-activated mouse macrophage cells (RAW 264.7); marinopyrone D (4) was inhibitory with an IC<sub>50</sub> value of 13 I``M. To our knowledge, marinopyrones A-C are only the second reported natural products from the rare halophi-lic genus Streptomonospora.

      • KCI등재

        Patchouli Alcohol, a Compound from Pogostemon cablin, Inhibits Obesity

        Jihye Lee,Byungwhi Kong,Seong-Ho Lee 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.3

        Obesity predisposes people to a variety of chronic metabolic diseases. Identification of natural factors that prevent the development of obesity is likely to be the most successful means of ameliorating the current obesity epidemic. Patchouli alcohol is a sesquiterpene alcohol found in Pogostemon cablin and possesses health benefit activities. This study was designed to examine if patchouli alcohol affects adipogenesis, and investigates the underlying mechanisms whereby patchouli alcohol exerts antiobesity effect. 3T3-L1 adipocytes were differentiated with treatment of different concentrations of patchouli alcohol. An in vivo study was performed to test the effect of patchouli alcohol gavage on a high-fat diet (HFD)-induced obesity. Treatment of patchouli alcohol reduced lipid accumulation in 3T3-L1 adipocytes in a dose-dependent manner without toxicity. Regarding mechanism, treatment of patchouli alcohol reduced expression of peroxisome proliferator-activated receptor-gamma (PPARγ) and CCAAT-enhancer-binding protein-alpha (C/EBPα) and increased expression of total and active β-catenin in 3T3-L1 adipocytes. Oral gavage of patchouli alcohol led to a significant reduction of body weight and fat accumulation in the mice fed with HFD. Transcriptome analysis indicates that smad7 is most highly activated gene in patchouli alcohol-treated 3T3-L1 cells. Patchouli alcohol possesses health benefit effect through inhibiting adipogenesis and fat tissue development.

      • SCIESCOPUS

        Pseudopolymorphs of LB30870, a Direct Thrombin Inhibitor: One-Dimensional Solvent Channel Structures Explain Reversible Hydration/Dehydration

        Lee, Jihye,Kim, Dongwook,Park, Jaehyeon,Kim, Eunice EunKyeong,Lah, Myoung Soo,Kim, Aeri The American Chemical Society 2018 CRYSTAL GROWTH AND DESIGN Vol.18 No.1

        <P>Three different hydrates of LB30870, a new direct thrombin inhibitor, were identified during the screening of solid form, and their interconversion relationship and relative thermodynamic stabilities were investigated. Form I (hexahydrate) changes to Form II (dihydrate) or Form III (tetrahydrate) by dehydration, while Form II becomes Form I by hydration, and both Form II and Form III change to Form I in the aqueous slurry. Single crystals obtained from two different crystallization conditions, wet or air-dried, were found to be isostructural with a difference in the solvent channels, and based on the simulated and experimental powder X-ray diffraction patterns, the air-dried crystals are assigned as Form I and Form III, respectively. In all crystal structures, LB30870 is in a folded conformation forced by the presence of strong hydrogen bonds by two structural water molecules. The solvent channel formed can hold up to six additional hydration water sites per each LB30870, and the one-dimensional solvent channel facilitates the interconversion among the hydrates and rapid conversion to Form I in water. Although all hydrate forms would not differ in oral bioavailability as Form I predominates in the aqueous phase, considering the stable water content at 40–75% relative humidity Form III would be the most suitable for further development.</P><P>Three different hydrates of LB30870, a new direct thrombin inhibitor, were identified, and their interconversion relationship and relative thermodynamic stabilities were investigated. LB30870 is in a folded conformation forced by the presence of strong hydrogen bonds by two structural water molecules, and the one-dimensional solvent channel facilitates the interconversion among the hydrates and rapid conversion to Form I in water.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cgdefu/2018/cgdefu.2018.18.issue-1/acs.cgd.7b00927/production/images/medium/cg-2017-00927h_0016.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cg7b00927'>ACS Electronic Supporting Info</A></P>

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