Investigating Various Factors Affecting the Long-Term Compressive Strength of Heat-Cured Fly Ash Geopolymer Concrete and the Use of Orthogonal Experimental Design Method

Hongen Zhang,Lang Li,Prabir Kumar Sarker,Tao Long,Xiaoshuang Shi,Qingyuan Wang,Gaochuang Cai 한국콘크리트학회 2020 International Journal of Concrete Structures and M Vol.14 No.1

This work quantified the hierarchy of the influence of three common mixture design parameters on the compressive strength and the rate of strength increase over the long term of low-calcium fly ash geopolymer concrete (FAGC) through designing 16 mixtures by the orthogonal experimental design (OED) method. The parameters used in the study were liquid to fly ash (L/FA) ratio, sodium hydroxide concentration (SHC) and sodium silicate solution to sodium hydroxide solution (SS/SH) ratio. The L/FA ratio showed little effect on compressive strength when it was varied from 0.40 to 0.52. SHC showed the greatest influence on compressive strength with little impact on the rate of strength increase after the initial heat curing. Even though the SS/SH ratio showed a small effect on the initial compressive strength, it had a considerable influence on the rate of strength increase over the long term. It was found that the compressive strength at 480 days was positively related to the Na₂O/SiO₂ molar ratio when it was varied from 0.49 to 0.80 and the Si/Al molar ratio was increased up to 1.87. Analysis of the failure types of specimens demonstrated that compressive strength of FAGC was associated with the strength of the mortar–aggregate interface zone (MAIZ).

Low-Intensity Shock Wave Therapy and Its Application to Erectile Dysfunction

Hongen Lei,Jing Liu,Huixi Li,Lin Wang,Yongde Xu,Wenjie Tian,Guiting Lin,Zhongcheng Xin 대한남성과학회 2013 The World Journal of Men's Health Vol.31 No.3

Although phosphodiesterase type 5 inhibitors (PDE5Is) are a revolution in the treatment of erectile dysfunction (ED) and have been marketed since 1998, they cannot restore pathological changes in the penis. Low-energy shock wave therapy (LESWT) has been developed for treating ED, and clinical studies have shown that LESWT has the potential to affect PDE5I non-responders with ED with few adverse effects. Animal studies have shown that LESWT significantly improves penile hemodynamics and restores pathological changes in the penis of diabetic ED animal models. Although the mechanisms remain to be investigated, recent studies have reported that LESWT could partially restore corpus cavernosum fibromuscular pathological changes, endothelial dysfunction, and peripheral neuropathy. LESWT could be a novel modality for treating ED, and particularly PDE5I non-responders with organic ED, in the near future. However, further extensive evidence-based basic and clinical studies are needed. This review intends to summarize the scientific background underlying the effect of LESWT on ED.

Recovery of mortar-aggregate interface of fire-damaged concrete after post-fire curing

Lang Li,Hong Zhang,Jiangfeng Dong,Hongen Zhang,Pu Jia,Qingyuan Wang,Yongjie Liu 사단법인 한국계산역학회 2019 Computers and Concrete, An International Journal Vol.24 No.3

In order to investigate the strength recovery of fire-damaged concrete after post-fire curing, concrete specimens were heating at 2°C/min or 5°C/min to 400, 600 and 800°C, and these exposed specimens were soaked in the water for 24 hours and following by 29-day post-fire curing. The compressive strength and split tensile strength of the high-temperature-exposed specimens before and after post-fire curing were tested. The proportion of split aggregate in the split surfaces was analyzed to evaluate the mortar-aggregate interfacial strength. After the post-fire curing process, the split tensile strength of specimens exposed to all temperatures was recovered significantly, while the recovery of compressive strength was only obvious within the specimens exposed to 600°C. The tensile strength is more sensitive to the mortar-aggregate interfacial cracks, which caused that the split tensile strength decreased more after high-temperature exposure and recovery more after post-fire curing than the compressive strength. The mortar-aggregate interfacial strength also showed remarkable recovery after post-fire curing, and it contributed to the recovery of split tensile strength.

Molecular and Cellular Microbiology / Biomedical Sciences : Isorhamnetin Attenuates Staphylococcus aureus-Induced Lung Cell Injury by Inhibiting Alpha-Hemolysin Expression

( Lanxiang Jiang ),( Hongen Li ),( Laiying Wang ),( Zexin Song ),( Lei Shi ),( Wenhua Li ),( Xuming Deng ),( Jianfeng Wang ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.3

Staphylococcus aureus, like other gram-positive pathogens, has evolved a large repertoire of virulence factors as a powerful weapon to subvert the host immune system, among which alpha-hemolysin (Hla), a secreted pore-forming cytotoxin, plays a preeminent role. We observed a concentration-dependent reduction in Hla production by S. aureus in the presence of sub-inhibitory concentrations of isorhamnetin, a flavonoid from the fruits of Hippophae rhamnoides L., which has little antibacterial activity. We further evaluate the effect of isorhamnetin on the transcription of the Hla-encoding gene hla and RNAIII, an effector molecule in the agr system. Isorhamnetin significantly down-regulated RNAIII expression and subsequently inhibited hla transcription. In a co-culture of S. aureus and lung cells, topical isorhamnetin treatment protected against S. aureus-induced cell injury. Isorhamnetin may represent a leading compound for the development of anti-virulence drugs against S. aureus infections.

Influence of structural system measures on the dynamic characteristics of a multi-span cable-stayed bridge

Fangfang Geng,Youliang Ding,Hongen Xie,Jianyong Song,Wanheng Li 국제구조공학회 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.52 No.1

A three-dimensional finite element model for the Jiashao Bridge, the longest multi-span cablestayed bridge in the world, is established using the commercial software package ANSYS. Dynamic characteristics of the bridge are analyzed and the effects of structural system measures including the rigid hinge, auxiliary piers and longitudinal constraints between the girders and side towers on the dynamic properties including modal frequency, mode shape and effective mass are studied by referring to the Jiashao Bridge. The analysis results reveal that: (i) the installation of the rigid hinge significantly reduces the modal frequency of the first symmetric lateral bending mode of bridge deck. Moreover, the rigid hinge significantly changes the mode shape and effective mass of the first symmetric torsional mode of bridge deck; (ii) the layout of the auxiliary piers in the side-spans has a limited effect on changing the modal frequencies, mode shapes and effective masses of global vibration modes; (iii) the employment of the longitudinal constraints significantly increases the modal frequencies of the vertical bending modes and lateral bending modes of bridge deck and have significant effects on changing the mode shapes of vertical bending modes and lateral bending modes of bridge deck. Moreover, the effective mass of the first anti-symmetric vertical bending of bridge deck in the longitudinal direction of the fully floating system is significantly larger than that of the partially constrained system and fully constrained system. The results obtained indicate that the structural system measures of the multi-span cable-stayed bridge have a great effect on the dynamic properties, which deserves special attention for seismic design and wind-resistant design of the multi-span cable-stayed bridge.

Influence of structural system measures on the dynamic characteristics of a multi-span cable-stayed bridge

Geng, Fangfang,Ding, Youliang,Xie, Hongen,Song, Jianyong,Li, Wanheng Techno-Press 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.52 No.1

A three-dimensional finite element model for the Jiashao Bridge, the longest multi-span cable-stayed bridge in the world, is established using the commercial software package ANSYS. Dynamic characteristics of the bridge are analyzed and the effects of structural system measures including the rigid hinge, auxiliary piers and longitudinal constraints between the girders and side towers on the dynamic properties including modal frequency, mode shape and effective mass are studied by referring to the Jiashao Bridge. The analysis results reveal that: (i) the installation of the rigid hinge significantly reduces the modal frequency of the first symmetric lateral bending mode of bridge deck. Moreover, the rigid hinge significantly changes the mode shape and effective mass of the first symmetric torsional mode of bridge deck; (ii) the layout of the auxiliary piers in the side-spans has a limited effect on changing the modal frequencies, mode shapes and effective masses of global vibration modes; (iii) the employment of the longitudinal constraints significantly increases the modal frequencies of the vertical bending modes and lateral bending modes of bridge deck and have significant effects on changing the mode shapes of vertical bending modes and lateral bending modes of bridge deck. Moreover, the effective mass of the first anti-symmetric vertical bending of bridge deck in the longitudinal direction of the fully floating system is significantly larger than that of the partially constrained system and fully constrained system. The results obtained indicate that the structural system measures of the multi-span cable-stayed bridge have a great effect on the dynamic properties, which deserves special attention for seismic design and wind-resistant design of the multi-span cable-stayed bridge.