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- 저자 : Zufry Hendra (검색결과 3 건)
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( Hendra Zufry ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: The use of Core Needle Biopsy (CNB) as complementary test to diagnose thyroid nodules has been minimally reported and is currently being investigated. The aims of this study to investigate the utility and patient comfort of Ultrasonography- Guided CNB for thyroid nodules based on Bethesda System. Methods: Sixty-five patients of thyroid nodule with inconclusive and follicular neoplasm data reported by fine-needle aspiration (FNA), divided to 32 patients undergone CNB with a 18-gauge, 7.5 cm, 1.1 and 1.6 cm specimen cutter TSK Acecut Automatic Biopsy Gun and 33 patients who refusing CNB were tested repeat FNA with a 23-gauge needle.. We used Visual Analog Scale (VAS) and Questioner to investigate patient comfort. Results: From the follow-up, the overall rate of malignancy was of 78.5 % (CNB 84.3 %; FNA 72.7 %), with the diagnosis accuracy of CNB was significantly (P < 0.05) higher than that of FNA. Mild Pain was reported in 87.5 % of CNB patient; 84.8 % of FNA patients. Local pain after biopsy was reported in 30.3 % of FNA and 50 % of CNB patients. Conclusions: This study has supported the assumption that CNB more useful than repeat FNA in thyroid nodules with inconclusive results, improving the diagnostic performance for malignancy, safely and comfort procedure.
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Zufry Hendra,Hariyanto Timotius Ivan 대한영상의학회 2024 Korean Journal of Radiology Vol.25 No.3
Objective: The current body of evidence lacks clarity regarding the comparative efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) as minimally invasive treatments for benign thyroid nodules. The primary objective of this study is to clarify these concerns. Materials and Methods: A comprehensive search was conducted using the Cochrane Library, Scopus, Europe PMC, and Medline databases until October 10th, 2023, using a combination of relevant keywords. This study incorporated literature that compared RFA and MWA for benign thyroid nodules. The primary outcome was the volume reduction ratio (VRR) from baseline to follow-up. Secondary outcomes were symptom score, cosmetic score, ablation time, major complications rate, hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. We used Risk of Bias in Non-randomized Studies - of Interventions (ROBINS-I) tool to assess the risk of bias in the included studies. We employed random effects models to analyze the standardized mean difference (SMD) and odds ratio for the presentation of outcomes. Results: Nine studies with 2707 nodules were included. The results of our meta-analysis indicated similar efficacy between RFA and MWA in terms of VRR during the 1 (SMD 0.06; 95% confidence interval [CI]: -0.13 to 0.26; P = 0.52) and 3 (SMD 0.11; 95% CI: -0.03 to 0.25; P = 0.12) months of follow-up. VRR was significantly higher in RFA than in MWA at the 6 (SMD 0.25; 95% CI: 0.06–0.43; P = 0.008) and 12 month of follow-up (SMD 0.38; 95% CI: 0.17 to 0.59; P < 0.001). There were no significant differences between RFA and MWA in symptom scores, cosmetic scores, or the incidence of complications, including hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. Conclusion: RFA showed a higher VRR than MWA at 6 and 12-month follow-ups, with a comparable safety profile.
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( Ganis Irawan ),( M Riswan ),( Krishna Sucipto ),( Hendra Zufry ),( Desi Salwani ),( Muslim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Hemophagocytic syndrome (HPS) is a rare, life-threatening, hematologic disorder which might arises secondary to infection, autoimmune disease or malignancy. It is most often characterized by prolonged fever, splenomegaly, and cytopenia of at least two lineages. Splenic tuberculosis is a rare form of extrapulmonary tuberculosis. No particular set of clinical symptoms or imaging findings is characteristic for splenic tuberculosis. We are reporting a case of HPS associated with splenic tuberculosis in 36 year old male who was admitted to our hospital due to persistent fever for the past 3months. He complained of distended belly, weakness, night sweats and weight loss. He lives in a rural village which is known to be an endemic area of malaria and tuberculosis. Histopathological examination of spleen tissue supported the diagnosis of splenic tuberculosis. Diagnosis of HPS were established by the presence of fever, splenomegaly, pancytopenia, hypofi brinogenemia and serum ferritin level more than 500 μg/l. Additional supportive evidences were hepatomegaly, elevated lactate dehydrogenase and slightly-hypoplastic marrow.
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