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Fan Zhuanzhuan,Weizhong Xu,Ruofei Wang,Huaping Wu,Aiping Liu 한국고분자학회 2023 Macromolecular Research Vol.31 No.6
Hydrogel actuators have potential applications in many fields because of their multiple responsiveness to environmental stimuli. However, it is still very challenging to design a hydrogel actuator with simple preparation, fast response, and good mechanical properties. In this work, a facile and convenient method to obtain a fast responsive hydrogel actuator has been successfully developed by embedding uniform inorganic particles into Poly(N-isopropylacrylamide) hydrogel network to form an asymmetric structure. By controlling the types and contents of inorganic particles, a wide range of adjustable actuation property can be achieved. At the same time, the introduction of inorganic particles greatly increases the mechanical properties of hydrogels, which is also very important for actuation performance improvement of hydrogel actuators. The optimized hydrogel exhibits relatively fast bending deformation under thermal stimulation (60 ℃), with a bending velocity of about 13.0° s−1 within first 10 s and a bending amplitude of about 328.1° within 1 min. The hydrogel can be designed to be temperature-controlled claw actuators with programmable shapes, indicating its application prospects in encapsulating, grasping, and transporting objects in water environment.
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Yan Xue,Zhuanzhuan Wu,Bo Li,Gang Sun,Fengyu Jia,Kai Liu 대한신경과학회 2023 Journal of Clinical Neurology Vol.19 No.5
Background and Purpose This study aimed to determine the changes in cerebral blood flow (CBF) in patients who received different durations of hemodialysis (HD) using arterial spin labeling magnetic resonance imaging. Methods The study included 46 patients who received HD and 24 demographically similar healthy controls (HCs). Patients who received HD were divided into three subgroups based on its duration: HD-1 (n=15, dialysis duration ≤24 months), HD-2 (n=16, dialysis duration >24 and ≤72 months), and HD-3 (n=15, dialysis duration ≥73 months). All subjects completed the Mini Mental State Examination and Montreal Cognitive Assessment tests, and the patients who received HD underwent laboratory tests. Group-level differences in the global and regional CBFs between patients who received HD and HCs were assessed. Correlation analysis was performed to evaluate the associations among CBF, clinical variables, and cognitive function. Results Compared with HCs, global and regional CBFs were significantly increased in the HD-1 and HD-2 groups (p<0.05), but there was no significant difference in the HD-3 group (p>0.05). However, compared with the HD-1 group, the HD-3 group had significantly decreased global and regional CBFs (p<0.05). The cognitive function was worse in patients who received long-term HD than in HCs. Increased dialysis duration and hemoglobin level were predictive risk factors for decreased CBF in patients who received long-term HD. Conclusions Patients who received long-term HD with normal CBF had worse cognitive function, which may be related to increased dialysis duration.
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