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- 저자 : Zhu Shaohui (검색결과 4 건)
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Yushan Zhu,Xiaoling Wang,Shaohui Deng,Mengqi Zhao,Xuefei Ao 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.7
Because of the concealment and uncertainty of dam foundation grouting, the accurate evaluation of the quality of grouting construction is a major concern. Most of the previous studies pertaining to the assessment of grouting efficiency only take a single factor into account, and only a few efforts have been devoted to the comprehensive evaluation of grouting efficiency, which fail to consider the fuzziness problems caused by the complex relationships among indicators as well as the randomness problems caused by subjective consciousness. Therefore, the curtain grouting efficiency evaluation method considering the uncertainty in evaluation process is proposed which includes three main parts: 1) Based on conventional evaluation indicators of grouting efficiency, where groutability is introduced as a new indicator; 2) a fuzzy comprehensive evaluation method based on cloud model is developed, by which the fuzziness and randomness in assessment are organically combined; and 3) the fuzzy entropy was calculated for indicating the complexity of grouting efficiency level. Then, the proposed method is used to assess efficiency of the curtain grouting for a hydropower station in China, and compared with three other methods. The outcomes display the consistency, representativeness, robustness and superiority of this evaluation method, which make the evaluation results more scientific and objective.
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Probabilistic Risk Assessment of RCC Dam Considering Grey-Stochastic-Fuzzy Uncertainty
Wenlong Chen,Xiaoling Wang,Minghui Liu,Yushan Zhu,Shaohui Deng 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.11
Greyness, randomness and fuzziness are three inseparable uncertainty factors influencing the safety of a roller compacted concrete dam (RCC dam), which can be regarded as a system reliability problem associated with multiple failure modes. Aiming at the current probabilistic risk analysis of RCC dams, most of the studies limited to single failure mode and single uncertainty. A probabilistic risk assessment method for dam under Grey-Stochastic-Fuzzy (GSF) uncertainty is proposed to consider the randomness and greyness of parameters and the fuzziness of the failure criteria. First, the fault tree model of an RCC dam is established based on Fault Tree Analysis (FTA). Then, bootstrap repeated sampling is embedded into grey system theory to quantify the grey properties of stochastic variables. The Latin Hypercube Sampling (LHS) function is improved to compensate for the inability of describing the fuzzy failure criteria. Finally, considering the correlated multiple failure modes, the proposed method is applied to analyze the parameter sensitivity and failure probability of the LDL dam in China. The results show that the proposed method is a high-efficiency, fastconvergence and more scientific method with reasonable outputs compared to common uncertainty probability analysis methods. The proposed method also provides an effective basis for the structural design and safety analysis of a concrete dam.
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Zhi Zheng,Jung Kuk Park,Linjuan Jiang,Shaohui Zhu,권오욱,이병천,이혜민,노연진,강재현,박병희 한국식품영양과학회 2023 Journal of medicinal food Vol.26 No.2
Red chili pepper is a beneficial natural spicy food that has antiobesity and antitype II diabetes effects, but it is not conducive to in-depth research as a dietary strategy to treat obesity. This study aims to investigate the beneficial effects of red chili pepper, fermented with a novel Lactococcus lactis subs. cremoris RPG-HL-0136. LC-MS/MS analysis is conducted to detect the content of capsaicin and dihydrocapsaicin, and no significant difference is observed between the nonfermented red chili pepper (NFP) (W/W) and the prepared L. lactis subs. cremoris RPG-HL-0136-fermented chili mixture (LFP). After establishing a high-fat diet-induced obese type II diabetic mouse model, the effects on weight gain, weight loss of liver and testicular fat, total cholesterol, triglyceride, fasting glucose, insulin, and homeostatic model assessment for insulin resistance in LFP were evaluated to be better than those in NFP following 10 weeks of interventions. All animal experiments were approved by the Institutional Animal Care and Use Committee of Xinxiang medical university. NFP and LFP could increase the expression of transient receptor potential vanilloid subfamily 1, peroxisome proliferator-activated receptor-alpha and caspase-2 in the high-fat mice. Compared with unfermented red chili pepper, the fermented red chili pepper complex significantly reduced LPS, tumor necrosis factor-alpha, and interleukin-6 in serum (P < .05). Intake of LFP significantly increased the expression of claudin-1 and occludin in the colon of the high-fat mice (P < .05), and there was no damage to the stomach and colon. This study provides scientific evidence that red chili pepper, fermented with L. lactis subs. cremoris RPG-HL-0136, may be beneficial for future treatment of obesity and accompanying diabetes. (IACUC.No.XYLL-20200019).
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The Risk of Gastrointestinal Cancer on Daily Intake of Low-Dose BaP in C57BL/6 for 60 Days
Zheng Zhi,Park Jung Kuk,Kwon Oh Wook,Ahn Sung Hoon,Kwon Young Joo,Jiang Linjuan,Zhu Shaohui,Park Byoung Hee 대한의학회 2022 Journal of Korean medical science Vol.37 No.30
Background: Benzo(a)pyrene (BaP) is a carcinogenic compound in contaminated foodstuffs. The effect of oral intake of the environmental carcinogen BaP under low doses and frequent exposure on a digestive system has not been thoroughly verified. Methods: In this regard, this study was conducted to prove the toxicity effects of BaP on the stomach and colon tissue after exposure to C57BL/6 mouse (3 and 6 µg/kg) following daily oral administration for 60 days. This study investigated acute gastric mucosal injury, severe gastric edema, cell infiltration, and mononuclear cells, multifocal cells, and tumoral inflammatory cells. Results: The results of ELISA showed that the expression of serum interleukin (IL)-6 and tumor necrosis factor-α in the BaP exposure group were significantly increased, and a high level of DNA adduct distribution in their stomach and colon. Moreover, this study has confirmed the expression of early carcinogenesis markers: nuclear factor (NF)-κB, p53, IL-6, superoxide dismutase 1 (SOD1), mucin (MUC1 and MUC2), and β-catenin in the stomach and colon, and showed that there was a significant increase in IL-6, NF-κB, SOD1, β-catenin, and MUC1 (P < 0.05). At the same time, there was a significant decrease in MUC2 and p53 (P < 0.05). Thus, even in low doses, oral intake of BaP can induce DNA damage, increasing the potential risk of gastrointestinal cancer. Conclusion: This study will provide a scientific basis for researching environmental contaminated food and intestinal health following daily oral administration of BaP.
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