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RISS 인기검색어
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Pricing Strategy of Dual Channel Supply Chain under Asymmetric Information
Zhou Yongwei,Fan Hehua 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.11
Aiming at the dual channel supply chain which sells a single product, and composed of the retailer as the leader and the manufacturer as the follower, firstly, by establishing the Stackelberg game model, we study the manufacturer and the retailer’s optimal pricing strategy under the condition of retailer’s innovation cost coefficient is common knowledge, then further analyze the manufacturer and the retailer’s optimal pricing strategy under the retailer’s innovation cost coefficient is his own private information, and discuss the existence condition of perfect Bayesian Nash equilibrium pricing. The research result showed that under the condition of asymmetric information, even the manufacturer has belief revision, his optimal pricing is always consistent with the type of retailer’s optimal pricing, but there are several pricing strategy choices to retailer. Under different parameters’ values, the dynamic game model with asymmetric information possibly exist separating equilibrium, pooling equilibrium, and semi-separating equilibrium.
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Xingwang Zhou,Jia Zhou,Yongwei Yu,Jiangquan Ma,Xueni Sun,Lanmei Hu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.10
In this research, a series of catalysts based on MoSe2 were synthesized by the hydrothermal method and used for the catalytic hydrogenation of alkali lignin for the first time. For 4 wt.% NiSe2/MoSe2 catalyst, at 290 ℃, under 2MPa H2 pressure for 1.5 h, the conversion of alkali lignin and the yield of bio-oil reached 96.47% and 93.68%, respectively. In addition, the composition of the product (bio-oil) was analyzed via Fourier transform infrared (FTIR) spectrometry, gas chromatography-mass spectrometry (GC-MS) spectra, and proton nuclear magnetic resonance (1HNMR) spectra. Finally, our study demonstrated that those MoSe2-based composite catalysts can effectively degrade the biomass into bio-oil containing valuable chemical products.
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Effects of Loading Rates on the Hysteretic Response of Resilient Variable Friction Dampers
Yongwei Wang,Zhen Zhou,Linjie Huang 한국강구조학회 2021 International Journal of Steel Structures Vol.21 No.5
A novel resilient variable friction damper (RVFD) with a simple construction was proposed. To analyze the eff ects of loading rate on the stability and energy dissipation performance of the RVFD, two RVFDs were tested under diff erent loading rates and the hysteretic behaviors of the compared with that of the traditional constant friction dampers. Then the peak force, energy dissipation behavior, uneven gap opening of the grooved outer plates (GOPs), and performance of the disc springs under diff erent loading rates were studied. The results show that although no self-centering system was provided, only the RVFDs without a self-centering system still can exhibit stable self-centering performance and eff ective energy dissipation behaviors, especially with due to the using e of athe grooved steel plates with greater groove angle. When the loading rate is less than 10 mm/s, the peak forces of the RVFD slightly decrease with the increase in loading rates, while when the loading rate is greater than 10 mm/s, its eff ects could be neglected. The uneven gap opening of the GOPs infl uences the clamping forces of the disc springs in the bolts under diff erent loading amplitudes. The disc springs in the RVFDs not only provide the increasing clamping forces for energy dissipation and the restoring forces for self-centering behavior, but also dissipate the energy, which accounts for about 10% of the total energy dissipation of the RVFD.
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하해찬,장지민,ZHOU DAN,김한결,백문정,신인철,윤소윤,Yongwei Piao,최종민,원종훈,김대경 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.10
Drug repositioning is a strategy that explores new pharmaceutical applications of previously launched or failed drugs, and is advantageous since it saves capital and time. In this study, we examined the inhibition of TLR2 signaling by drug candidates. HEK-BlueTM-hTLR2 cells were pretreated with drugs and stimulated using the TLR2 ligand, Pam3CSK4. Among the drugs that inhibited TLR2 signaling, we selected TRIAC, which is yet to be patented. Pretreatment with TRIAC decreased the TLR2 level and the phosphorylation of Akt and MAPKs in HEK-BlueTM- hTLR2 cells. Since TLR2 is overexpressed in patients with acute hepatitis, we confirmed that TRIAC alleviates necrosis in a mouse model of Con A-induced acute hepatitis. The serum AST and ALT levels are indicators of liver damage, and are increased in Con A-induced hepatitis. Additionally, TLR2 and inflammatory cytokine levels are increased following administration of Con A and lead to liver damage. TRIAC decreased the serum levels of AST and ALT, and reduced liver tissue necrosis in mice with Con A-induced acute fulminant liver damage, by reducing the levels of inflammatory cytokines. In conclusion, TRIAC alleviates inflammation in mouse models of Con A-induced hepatitis by inhibiting the phosphorylation of Akt and MAPKs, the sub-mechanisms underlying TLR2 signaling.
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