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        Study on mass transfer and heat transfer in transition zone of short-path distillation separation equipment based on N-dodecanol and N-hexadecanol

        Zhenya Duan,Haodong Zhang,Bin Liu,Zhiwei Sun,Junmei Zhang,Longlong Lin 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.2

        Based on the fact that the distance between the heat exchange surfaces has little influence on the separation efficiency in the short-path distillation, a hypothesis that the heat and mass transfer process in the transition region is controlled by heat convection is proposed; the gas-liquid state in the transition zone was calculated by numerical simulation experiment. The results show that the gas-liquid volume fraction and temperature fluctuation in the evaporation and condensation process is unstable, while the gas-liquid volume fraction and temperature fluctuation in the transition zone is stable in the short-path distillation process. It can be concluded that in unsteady thermodynamics, the transition zone is a stable convective heat transfer process that is not affected by the distance between heat transfer surfaces. Thus, under ideal conditions, the continuous extension of the transition region has little effect on the distillation efficiency.

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        Study on the performance of different discharging devices of a continuous production system

        Zhenya Duan,Jie Wang,Shujie Sun,Wenchen Li,Haodong Zhang,Guoyue Qiao,Junmei Zhang,Jingtao Wang 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.4

        Based on the developed continuous production system of sodium phenol carboxylation reaction, severaltypes of discharging devices are proposed, which are suitable for the case where the transported particles are not easyto maintain a stable state in the transported fluid. Numerical simulations of the gas-solid two-phase flow characteristicsand particle distribution were performed with DPM, and the particle retention ratio and fluid loss degree were proposedto investigate the performance of the discharging devices. The results of simulations and industrial experimentsshowed that a guide plate installed in the “B” discharging device can solve the accumulation problem, realize the efficientand continuous delivery of the particles, and maintain a uniform distribution of particles. This study can providea reference for the design of a gas-solid two-phase discharging device, and guide the industrial experimental operationand modification of continuous production systems for sodium phenol carboxylation.

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        Dependency of Portevin-LeChatelier Effect and Microstructure Characteristics of 9Cr ODS Steels on Strain Rates Upon Hot Deformation

        Xiaosheng Zhou,Yaran Zhang,Yanmo Li,Meini Yuan,Guodong Li,ZhenYa Chen,Huang Zhang 대한금속·재료학회 2024 METALS AND MATERIALS International Vol.30 No.1

        The flow stress and microstructure evolution of 9Cr oxide dispersion strengthened (ODS) steels were investigated by isothermalcompression at 1000–1150 oC with strain rates from 0.001 to 1 s−1. Microstructure characteristics of ODS steelsunder various condition were studied using the EBSD and TEM techniques. At each deformation temperature, PortevinLe--Chatelier (PLC) effect characteristics of repeated serrated stress was observed, as the strain rates were 0.01, 0.1 and 1 s−1. The serrations fluctuated about the mean flow curve in quick succession, and the critical strain for the PLC effect was relatedto both the deformation temperature and strain rates. The stress drops at strain rates of 0.01 and 0.1 s−1 were smaller thanthose at 1 s−1. The strain rate affected the dynamic recovery and recrystallization of austenite grains, as well as the texturecomponents of martensite transformed from austenite. Cap-shaped oxide particles in as-fabricated and hot deformed steelswere characterized in detail. The cap parts of cap-shaped oxide particles were depleted of alloying elements, and the capswere crystal or amorphous. Large-sized oxide particles were easier to be deformed than small-sized ones. Despite of theoxide deformation, the PLC effect was still suggested to be related to the solute-dislocation interaction.

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        Evaluation of the Immunomodulatory and Anti-inflammatory Activities of Honey Bee Larva Powder

        Kejuan Li,Shuang Sun,Masakatsu Kageyama,Long Xiao,Guoqing Xing,Ran Gao,Fengming You,Xi Fu,Zhenya Zhang 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.7

        Honey bee larva powder (HLP) has traditionally been used as a daily supplement and tonic for health promotion with an uncertain scientific basis. In this study, B16-F10 tumor-bearing mice were established to evaluate the immunomodulatory activity of HLP. The proliferation and apoptosis assays were performed to evaluate the anti-inflammatory activity of honey bee larva extract (HLE) in RAW 264.7 macrophage. The in vivo experimental results demonstrated that the oral administration of freeze-dried HLP (4 and 6 g/kg) significantly enhanced the spleen index, the percentage of CD4+cells, and the ratio of CD4+ and CD8+ T lymphocytes (CD4+/CD8+) in the peripheral blood compared with those in the tumor control mice. The in vitro studies demonstrated the potent immunomodulatory activities of HLE through the induction of RAW 264.7 macrophage proliferation and the mitigation of doxorubicin (DOX)-induced toxicity. HLE also exhibits anti-inflammatory activity by decreasing the production of nitric oxide (NO) and the cytokine level of interleukin-6 (IL-6) in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage. The present study provides important scientific evidence for the immunomodulatory and anti-inflammatory activities of HLP and HLE.

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