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RISS 인기검색어
- 검색키워드
- 저자 : Zhenxing Di (검색결과 5 건)
- 무료
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TRANSFER PROPERTIES OF GORENSTEIN HOMOLOGICAL DIMENSION WITH RESPECT TO A SEMIDUALIZING MODULE
Di, Zhenxing,Yang, Xiaoyan Korean Mathematical Society 2012 대한수학회지 Vol.49 No.6
The classes of $G_C$ homological modules over commutative ring, where C is a semidualizing module, extend Holm and J${\varnothing}$gensen's notions of C-Gorenstein homological modules to the non-Noetherian setting and generalize the classical classes of homological modules and the classes of Gorenstein homological modules within this setting. On the other hand, transfer of homological properties along ring homomorphisms is already a classical field of study. Motivated by the ideas mentioned above, in this article we will investigate the transfer properties of C and $G_C$ homological dimension.
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BALANCE FOR RELATIVE HOMOLOGY WITH RESPECT TO SEMIDUALIZING MODULES
Di, Zhenxing,Zhang, Xiaoxiang,Chen, Jianlong Korean Mathematical Society 2015 대한수학회보 Vol.52 No.1
We derive in the paper the tensor product functor -${\otimes}_R$- by using proper $\mathcal{GP}_C$-resolutions, where C is a semidualizing module. After giving several cases in which different relative homologies agree, we use the Pontryagin duals of $\mathcal{G}_C$-projective modules to establish a balance result for such relative homology over a Cohen-Macaulay ring with a dualizing module D.
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Balance for relative homology with respect to semidualizing modules
Zhenxing Di,Xiaoxiang Zhang,Jianlong Chen 대한수학회 2015 대한수학회보 Vol.52 No.1
We derive in the paper the tensor product functor $-\otimes_R-$ by using proper $\mathcal {G}\mathcal {P}_C$-resolutions, where $C$ is a semidualizing module. After giving several cases in which different relative homologies agree, we use the Pontryagin duals of $\mathcal {G}_C$-projective modules to establish a balance result for such relative homology over a Cohen-Macaulay ring with a dualizing module $D$.
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Transfer properties of Gorenstein homological dimension with respect to a semidualizing module
Zhenxing Di,Xiaoyan Yang 대한수학회 2012 대한수학회지 Vol.49 No.6
The classes of GC homological modules over commutative ring, where C is a semidualizing module, extend Holm and Jgensen's notions of C-Gorenstein homological modules to the non-Noetherian set-ting and generalize the classical classes of homological modules and the classes of Gorenstein homological modules within this setting. On the other hand, transfer of homological properties along ring homomorphisms is already a classical eld of study. Motivated by the ideas mentioned above, in this article we will investigate the transfer properties of C and GC homological dimension.
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Sun Di,Mou Shan,Chen Lifeng,Yang Jie,Wang Rongrong,Zhong Aimei,Wang Wei,Tong Jing,Wang Zhenxing,Sun Jiaming 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background: Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have been found to have a great potential for soft tissue repair due to various biological functions, including pro-angiogenesis and low immunogenicity. However, the low yield and heterogeneity of MSC-EVs limited their clinical transformation. This study was designed to develop a novel adipose-derived stem cell engineered nanovesicles (ADSC-NVs) with high production and explore its pro-angiogenetic effect and application in adipose tissue regeneration. Methods: Adipose-derived stem cell-derived extracellular vesicles (ADSC-EVs) were isolated from an EVs-free culture medium for human ADSCs (hADSCs). ADSC-NVs were prepared by sequentially extruding ADSCs followed by iodixanol density gradient ultracentrifugation and were compared with ADSC-EVs in morphology, size distribution, protein contents and yield. The pro-angiogenetic effect of ADSC-NVs in different doses (0, 5, 20 and 80 μg/mL) in vitro was determined using transwell assay, tube formation assay, western blot and qRT-PCR. In vivo, BALB/c nude mice were administered injection of a mixture of fat granules and different dose of ADSC-NVs and grafts were harvested at 12 weeks post-transplantation for further analysis. By analyzing the weight and volume of grafts and histological evaluation, we investigated the effect of ADSC-NVs in vessel formation and adipose tissue regeneration. Results: Our results showed yield of purified ADSC-NVs was approximately 20 times more than that of ADSC-EVs secreted by the same number of ADSCs. In vitro, both ADSC-NVs and ADSC-EVs exhibited a dose-dependent proangiogenetic effect, despite their distinct miRNA profiles. These effects of ADSC-NVs may be mediated by enriched miR-21-5p via PTEN inhibition and PI3K/p-Akt signaling activation. Furthermore, after a mixed injection of ADSC-NVs, vessel formation and adipose regeneration were observed in vivo in fat implants. Conclusions: Our study developed a potent alternative of ADSC-EVs. ADSC-NVs have a high pro-angiogenesis potential and can be used as cell-free therapeutic biomaterials in soft tissue regeneration.
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