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- 저자 : Yusuf Aydın (검색결과 3 건)
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Overall Cost Optimization of Prestressed Concrete Bridge using Genetic Algorithm
Zekeriya Aydın,Yusuf Ayvaz 대한토목학회 2013 KSCE JOURNAL OF CIVIL ENGINEERING Vol.17 No.4
Overall cost optimization of Prestressed Concrete (PC) bridges is investigated in this study. The purpose of this study is to determine the optimum span number and optimum cross-sectional properties of multi-span bridges. Considered bridge superstructure is constituted by adjacent simply supported pretensioned prestressed I-girders. Also, considered bridge substructure is constituted by single-column piers and rectangular spread footings. Span number, cross-section dimensions of prestressed girders and the area of Prestressing Steel (PS) are considered as design variables. PC girders, piers and footings are designed according to AASHTO Standard Specifications for Highway Bridges. A modified hybrid Genetic Algorithm (GA) is used for the optimum design. Working stress, ultimate strength, ductility limits, deflection, and geometry constraints are considered. Total cost of the bridge is taken as optimality criterion. A computer program is coded to perform optimum design and numerical examples from the application are designed. One of these examples is used in this paper. It is concluded that GA can be effectively used in the overall cost optimization of PC bridges.
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Recurrent and Massive Life Threatening Epistaxis due to Nasal Heroin Usage
Hüseyin Yaman,Yusuf Aydın,Süleyman Yılmaz,Elif Önder,Ender Güçlüm,Özcan Öztürk 대한이비인후과학회 2011 Clinical and Experimental Otorhinolaryngology Vol.4 No.3
Epistaxis, active bleeding from the nose, is a common ear nose and throat emergency, and can be severe or even fatal. We report a severe life threatening recurrent massive nasal bleeding caused by intranasal heroin use that has not hitherto been reported in the English literature. A 24-year-old male who took heroin several times nasally presented with massive nasal bleeding. A blood transfusion and an operation to halt nasal bleeding were required. The patient did not experience a bleeding attack 2 months following cessation of nasal heroin use.
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Cemil Çelik,Abdullah Bolu,Taner Öznur,Mehmet Sinan Aydın,Yusuf Tokgöz,Özcan Uzun 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.1
Objective: Myostatin is a growth factor which is investigated regarding musculoskeletal system. Albeit its effect on muscle mass is known, it is considered likely having other unknown effects as well, particularly on central nervous system. With this study, it is aimed to find out that what type of effect electroconvulsive therapy (ECT) does on myostatin in patients with treatment resistant depression. Methods: Twenty-nine patients with treatment resistant major depression and thirty healthy volunteers were included in the study. Pre- and post-ECT levels of myostatine were compared; also this results were compared to healthy controls. Results: For 29 patients with treatment-resistant major depression, the pre-treatment mean myostatin level was 0.95±0.32 ng/ml and post-therapy myostatin level was 11.05±6.97 ng/ml. As a result of this study, it is found that ECT affects serum myostatin levels to a significant degree (t=4.17, p<0.05). It is also found that there was a significant relation between serum myostatin levels and depression scores (r=0.392, p<0.05). Conclusion: With the present study and similar ones, it can be understood that how ECT achieves its effectiveness biologically.
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