http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Clinical Impact of MDR Pathogen during Bridge to Lung Transplantation
( Yunha Nam ),( Dong Kyu Oh ),( Tae Sun Shim ),( Kyun-wook Jo ),( Dong Kwan Kim ),( Sehoon Choi ),( Geun Dong Lee ),( Sung-ho Jung ),( Pil-je Kang ),( Seung-il Park ),( Sang-bum Hong ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-
Background As lung transplantation and extracorporeal membrane oxygenation (ECMO) are increasing in worldwide, bridge to lung transplantation (BTT) is also increasing and showing good Results. A few reports of lung transplantation, whether multidrug resistance (MDR) pathogens or not showed no difference of clinical outcome. However there are only a few reports about effects of MDR during BTT. Therefore, this study aimed to examine whether the presence of an MDR pathogen in the respiratory system before transplantation could affect clinical outcome. Methods We retrospectively analyzed medical records of adult patients who underwent ECMO before lung or heart-lung transplantation from 2011 to 2018 in Asan Medical center. Culture result performed in the respiratory system before transplantation were analyzed and divided into MDR and non-MDR groups to determine intensive care unit (ICU) stay, post-operation hospital duration, and post-operation ventilator duration. Results Of 41 patients, the median age was 55 years and 26 (63.4%) were male. MDR pathogen was identified in 20 patients, and MDR-Acinetobacter baumanii was cultured the most (13 patients, 31.7%) among pathogens. Pre-operative duration was longer in MDR group, about 14 [Interquartile range (IQR) 11-13] vs 10 [IQR 4-15] days (p=0.009). There was no difference in total ICU stay (43 [IQR 28-62] vs 33 [IQR 22-55], p=0.175), post-operation ICU stay (16 [9-25] vs 15 [11-35], p=0.638), post-operation hospital duration (64 [32-214] vs 60 [42-111], p=0.990), and post-operation ventilator duration (10 [5-18] vs 11 [6-31], p=0.744) between two groups. Also, there was no significant difference in 1-year survival between the two groups (70% vs 76%, p=0.462). Conclusion In patients who underwent BTT, even though the MDR pathogen was detected before transplantation, post-transplantation outcomes are no different.
전산해석을 통한 접선연소식 석탄화력 보일러의 암모니아 혼소 최적화 방안 연구
구윤하(Yunha Koo),강우석(Woosuk Kang),하선교(Seonkyo Ha),조현빈(Hyunbin Jo),박상빈(Sangbin Park),백세현(Sehyeon Baek),류창국(Changkook Ryu) 한국연소학회 2023 KOSCOSYMPOSIUM논문집 Vol.2023 No.5
In coal-fired power plants, NH₃ cofiring has emerged as a new strategy to reduce CO₂ emissions. For NH₃ cofiring, it is important to minimize NOx emissions while maintaining boiler performance in terms of flame stability, combustion efficiency, and heat distribution. In this study, various NH₃ co-firing methods of four different NH₃ inlet were evaluated using computational fluid dynamics in a commercial 500 MWe tangential-firing boiler. To suppress fuel NO formation, the burner zone stoichiometric ratio was kept low by increasing the air supply to the separated over-fire air, while the overall excess air ratio was fixed at 15%. Injecting NH₃ through the oil ports at the burner zone with burner zone stoichiometric ratio of 0.75-0.80 result in low NO emissions (194.8~204.8 ppm) while achieving similar combustion efficiency and heat distribution to the reference case of coal combustion only. Additionally, further optimization can be achieved in other cases with different injection locations through changes in secondary air distribution and NH₃ injection speed.
눈의 물리적인 특성과 유사한 펄 원료 개발 및 이를 이용한 화장료 조성물 제조방법
이윤하 ( Yunha Lee ),김경남 ( Kyung Nam Kim ),선우건 ( Gun Sunwoo ),( Norbert Rick ),( Antje Reichnek ),최영진 ( Yeongjin Choi ),고승용 ( Seungyong Ko ),한상훈 ( Sanghun Han ),강학희 ( Hakhee Kang ),이옥섭 ( Oksub Lee ) 대한화장품학회 2008 대한화장품학회지 Vol.34 No.3
화장품 분야에서 펄 안료는 다양하게 적용되어져 왔다. 지금까지 가장 대중적으로 사용된 펄 안료는 마이카 기재에 산화철이 코팅된 것이었지만, 최종 제품에 이와 같은 펄을 사용하게 될 경우 천연 마이카에 함유된 불순물로 인해 약간의 불투명한 노란 색상이 띄게 된다[1,2]. 본 연구는 눈과 같은 반짝임을 제공하는 펄 안료 개발에 초점을 맞췄고, 눈과 같은 효과는 펄 안료의 구조와 순도 등의 영향 때문인 것을 알게 되었다. 특히, 이번 펄 안료 개발은 유리 기재와 산화철을 코팅시켜 눈의 광학적인 값(refractive index)과 입자 크기(particle size)를 눈과 유사하게 개발하였고 이는 눈과 같이 화려한 반짝임(glittering) 효과를 구현할 수 있게 되었다. 그리고 메이크업 제품에 본 펄 안료를 적용하여 화려한 제품을 개발하게 되었다. Pearlescent pigments have been widely used in cosmetic applications. Up to date; the most widely used pearl effect pigment is the mica-based pigment, which uses natural mica as the substrate that is in turn coated with metal oxide interference layer. However, when natural mica is employed as a base material the final product often has a yellowish color, mainly due to the fact that natural mica contains low levels of iron as an impurity[1,2]. This study was focused on developing a pearl pigment which might have a similar sparkling effect as snow. This effect was found to be due to its structure and purity, and this concept was also applied to development of our pearl pigments. More specifically, this invented pearl effect pigments are the mixture of glass-flake and glass-flake coated metal oxides and present the optical properties of snow matrix such as refractive index and particle size, unlike only the glass-flake or glass-flake coated metal oxides to be applied in. Using base material having similar physical properties (refractive index and particle size) as snow matrix as platelet for pearl effect pigments, these invented pigments present a three-dimensional glittering effect of the snow matrix. With this invented pigments an applied; we achieved the beauty of snow crystal from makeup products containing these pigments.
접선연소식 석탄화력 보일러에서 최적 암모니아 혼소 방안에 대한 전산해석 연구
구윤하(Yunha Koo),박종민(Jongmin Park),강우석(Woosuk Kang),조현빈(Hyunbin Jo),박상빈(Sangbin Park),백세현(Sehyeon Beak),이종민(Jongmin Lee),류창국(Changkook Ryu) 한국연소학회 2022 KOSCOSYMPOSIUM논문집 Vol.2022 No.11
NH₃ co-firing has recently emerged as an urgent issue for CO₂ emission reduction by displacing the fossil fuel in coal-fired power plants. The ideal method for NH₃ cofiring requires to minimize the NOx emission while achieving similar boiler performance in terms of flame stability, combustion efficiency, and heat distribution. This paper presents the results of preliminary study for NH₃ co-firing with coal in a tangential-firing boiler using computational fluid dynamics. The location of NH₃ injection was varied between different parts across the burner zone while increasing the ratio of air supply to the separated over-fire air (SOFA). It was found that the NOx emission at the boiler exit greatly depends on the location of NH₃ injection, in which the lowermost burner was found ideal to keep the NOx emission at a similar level to that for coal combustion only. However, the distribution of secondary air requires further optimization because the heat absorption on the furnace wall (evaporator) reduced significantly.
500 MWe급 접선연소식 석탄화력 보일러의 암모니아 혼소 최적화를 위한 전산해석 연구
구윤하(Yunha Koo),강우석(Woosuk Kang),하선교(Seonkyo Ha),조현빈(Hyunbin Jo),백세현(Sehyun Baek),박경일(Kyeongil Park),류창국(Changkook Ryu) 한국연소학회 2023 KOSCOSYMPOSIUM논문집 Vol.2023 No.11
In coal fired power generation, cofiring ammonia replacing coal has emerged as a potential solution to mitigate carbon dioxide. For ammonia cofiring, it is important to minimize NOx emissions while maintaining boiler performance in terms of flame stability, combustion efficiency, and heat distribution. In this study, ammonia cofiring methods varying its inlet, speed, and direction were evaluated using CFD in 500 MWe tangential-firing pulverized coal boiler. To suppress fuel NO formation, secondary air supply around the ammonia inlet was moved to SOFA, resulting in burner zone stoichiometric ratio of 0.8, while the overall excess air ratio was fixed at 15%. When ammonia is injected from the lower part of the boiler where fireball begins to form, endothermic ammonia decomposition delays ignition/combustion of coal, leading to significant decrease in boiler performance. When ammonia is injected from the upper part of the burner zone, ammonia flow moves along the outside of the fireball where is oxygen-rich resulting in increase of ammonia oxidation. By increasing speed of ammonia, it can penetrate fuel-rich fireball leading to decrease in NO emissions. Furthermore, Injecting ammonia with opposite direction promotes the 연료 농후 and reactions of O₂ with unburned gases, while NO emission remains almost the same.
Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency
Kim, Yunha,Kang, Young-Sook,Lee, Na-Young,Kim, Ki Yoon,Hwang, Yu Jin,Kim, Hyun-Wook,Rhyu, Im Joo,Her, Song,Jung, Min-Kyung,Kim, Sun,Lee, Chai-Jin,Ko, Seyoon,Kowall, Neil W,Lee, Sean Bong,Lee, Junghee LANDES BIOSCIENCE 2015 AUTOPHAGY Vol.11 No.5
고기술산업과 저기술산업의 제품혁신패턴 및 연구개발 결정요인 분석: Hurdle 모형과 Heckman 표본선택모형을 중심으로
이윤하(Yunha Lee),강승규(Kang, Seung-Gyu),박재민(Jaemin Park) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.10
그간 진화경제학적 관점에서 산업 고유의 특성에 따라 발생하는 기술혁신 패턴을 고찰하고자 하는 시도가 있어왔다. 본 연구는 국내 제조업을 기술집약도에 따라 고기술산업과 저기술산업으로 구분하고 제품혁신 패턴 및 혁신 성과 결정요인의 산업별 차이를 확인하였다. 기존 연구들은 연구개발 수행에 대한 기업의 의사결정 과정에서 연구개발을 수행하도록 만드는 결정요인을 분석에 반영하지 못했다는 지적이 있다. 본 연구에서는 이러한 문제를 극복하기 위해서 Heckman 표본선택모형과 허들모형을 대안으로 제시하고, 「2014년 중소기업기술통계조사」 자료의 1,637개 기업에 대해 분석을 실시했다. 분석 결과 제조업의 중소기업이 수행하는 제품혁신 패턴과 제품혁신 성과에 영향을 미치는 결정요인들에 있어 고기술산업과 저기술산업 간 뚜렷한 차이가 있다는 것을 확인 할 수 있었다. 또한, 기존 연구의 한계점을 극복하기 위해 채택한 연구모형의 확장을 통해서 중소기업 연구개발 수행에 대한 의사결정 과정에서 표본선택편의 문제와 허들로 표현되는 문지방이 있다는 것을 발견할 수 있었다. 본 연구는 산업별 제품혁신 패턴의 특징과 제품혁신 성과결정요인을 다각적으로 살펴보았고, 중소기업의 연구개발 수행에 대한 의사결정 과정을 더 깊이 이해할 수 있었다는 점에서 학술적 의의가 있다. There have been many studies to examine the patterns in innovations reflecting industry-specific characteristics from an evolutionary economics perspective. The purpose of this study is to identify industry-specific differences in product innovation patterns and determinants of innovation performance. For this, Korean manufacturing is classified into high-tech industries and low-tech industries according to technology intensity. It is also pointed out that existing research does not reflect the decision-making process of firms" R&D implementations. In order to solve this problem, this study presents a Heckman sample selection model and a double-hurdle model as alternatives, and analyzes data from 1,637 firms in the 2014 Survey on Technology of SMEs. As a result, it was confirmed that the determinants and patterns of manufacturing in small and medium-size enterprise (SME) product innovation are significantly different between high-tech and low-tech industries. Also, through an extended empirical model, we found that there exist a sample selection bias and a hurdle-like threshold in the decision-making process. In this study, the industry-specific features and patterns of product innovation are examined from a multi-sided perspective, and it is meaningful that the decision-making process for manufacturing SMEs" R&D performance can be better understood.