http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yung-Chieh Tsai,Yen-Mei Lee,Sy-Ying Leu,Hsiao-Yen Chiang,Mao-Hsiung Yen,Pao-Yun Cheng,Chih-Hsiung Hsu 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-
Leptin is a peptide hormone, which has a central role in the regulation of body weight; it also exerts many potentially atherogenic effects. Ferulic acid ethyl ester (FAEE) has been approved for antioxidant properties. The aim of this study was to investigate whether FAEE can inhibit the atherogenic effects of leptin and the possible molecular mechanism of its action. Both of cell proliferation and migration were measured when the aortic smooth muscle cell (A10 cell) treated with leptin and/or FAEE. Phosphorylated p44/42MAPK, cell cycle-regulatory protein (for example, cyclin D1, p21, p27), β-catenin and matrix metalloproteinase-9 (MMP-9) proteins levels were also measured. Results demonstrated that leptin (10, 100 ng ml−1) significantly increased the proliferation of cells and the phosphorylation of p44/42MAPK in A10 cells. The proliferative effect of leptin was significantly reduced by the pretreatment of U0126 (0.5 μM), a MEK inhibitor, in A10 cells. Meanwhile, leptin significantly increased the protein expression of cyclin D1, p21, β-catenin and decreased the expression of p27 in A10 cells. In addition, leptin (10 ng ml−1) significantly increased the migration of A10 cells and the expression of MMP-9 protein. Above effects of leptin were significantly reduced by the pretreatment of FAEE (1 and 10 μM) in A10 cells. In conclusion, FAEE exerts multiple effects on leptin-induced cell proliferation and migration, including the inhibition of p44/42MAPK phosphorylation, cell cycle-regulatory proteins and MMP-9, thereby suggesting that FAEE may be a possible therapeutic approach to the inhibition of obese vascular disease.
Yung-Chung Chen,Yu-Yang Su,Sheng-Huei Hsiao 한국섬유공학회 2019 Fibers and polymers Vol.20 No.9
A series of fluorinated poly(ether imide)s (PEIs) were prepared from asymmetry, bulky featured of 1,2-bis(3,4-dicarboxyphenoxy)-4-tert-butylbenzene dianhydride and various trifluoromethyl-based bis(ether amine)s via conventionalthermal (H) or chemical (C) imidization. All fluorinated PEIs exhibited flexible, good mechanical properties and excellentsolubility in a variety of organic solvents. In addition, the chemical imidization based PEI thin films showed cut-offwavelengths of UV-vis absorptions below 380 nm with very low yellowness index (b* < 5.5). They also exhibited highthermal stability with the 10 % weight loss temperature from 486 to 550 oC of in nitrogen or air atmosphere. Compared withthe corresponding PEIs based on non-fluorinated bis(ether amine)s, fluorinated PEIs not only showed higher opticaltransparency, lower dielectric constants and water absorptions but also maintained thermal and mechanical properties.
Properties of recycled green building materials applied in lightweight aggregate concrete
Her-Yung Wang,Darn-Horng Hsiao,Shi-Yang Wang 사단법인 한국계산역학회 2012 Computers and Concrete, An International Journal Vol.10 No.2
This study uses recycled green building materials based on a Taiwan-made recycled mineral admixture (including fly ash, slag, glass sand and rubber powder) as replacements for fine aggregates in concrete and tests the properties of the resulting mixtures. Fine aggregate contents of 5% and 10% were replaced by waste LCD glass sand and waste tire rubber powder, respectively. According to ACI concretemixture design, the above materials were mixed into lightweight aggregate concrete at a constant water-tobinder ratio (W/B = 0.4). Hardening (mechanical), non-destructive and durability tests were then performed at curing ages of 7, 28, 56 and 91 days and the engineering properties were studied. The results of these experiments showed that, although they vary with the type of recycling green building material added, the slumps of these admixtures meet design requirements. Lightweight aggregate yields better hardened properties than normal-weight concrete, indicating that green building materials can be successfully applied in lightweight aggregate concrete, enabling an increase in the use of green building materials, the improved utilization of waste resources, and environmental protection. In addition to representing an important part of a “sustainable cycle of development”, green building materials represent a beneficial reutilization of waste resources.
Lin, Cheng-Yung,Kuo, Hsiao-Yun,Wan, Tien-Chun Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.6
Experiments were conducted to evaluate the effect of an outdoor-grazed raising model on meat composition, physical properties and sensory attributes of Taiwan game hens. Six hundred 1-d old female chicks were raised on a floor for 8 weeks. On day 57, 600 healthy birds, with similar body weight, were selected and randomly assigned to three treatment groups (cage, floor-pen and free-range). The results showed that different feeding models had no effect on drip loss, cooking loss, moisture, crude protein, crude fat, crude ash, zinc and calorie contents in breast meat and moisture content in thigh meat. The free-range group had the lowest fat content in both breast and thigh meat, and the lowest calorie content in thigh meat. The firmness and toughness in both thigh and breast of the free-range group were the highest values (p<0.05). The crude protein, total collagen, zinc and iron contents in thigh meat and total collagen content in breast meat of the free-range group were significantly higher than those of the cage-feeding group (p<0.05). The meat sensory scores of flavor, chewiness and overall acceptability of both thigh and breast meat of the free-range group were significantly (p<0.05) better than those of the other two groups. Moreover, the current findings also indicate that the Taiwan game hens of the free-range feeding model displayed well-received carcass traits and meat quality, with higher scores for flavor, chewiness and overall acceptability for greater sensory satisfaction in both breast and thigh meat. In addition, the thigh meat contained high protein and total collage but low fat, offering a healthier diet choice.
Development of Composite Load Models of Power Systems using On-line Measurement Data
Byoung-Kon Choi,Hsiao-Dong Chiang,Yinhong Li,Yung-Tien Chen,Der-Hua Huang,Mark G. Lauby 대한전기학회 2006 Journal of Electrical Engineering & Technology Vol.1 No.2
Load representation has a significant impact on power system analysis and control results. In this paper, composite load models are developed based on on-line measurement data from a practical power system. Three types of static-dynamic load models are derived: general ZIP-induction motor model, Exponential-induction motor model and Z-induction motor model. For the dynamic induction motor model, two different third-order induction motor models are studied. The performances in modeling real and reactive power behaviors by composite load models are compared with other dynamic load models in terms of relative mismatch error. In addition, numerical consideration of ill-conditioned parameters is addressed based on trajectory sensitivity. Numerical studies indicate that the developed composite load models can accurately capture the dynamic behaviors of loads during disturbance.
Development of Composite Load Models of Power Systems using On-line Measurement Data
Choi Byoung-Kon,Chiang Hsiao Dong,Li Yinhong,Chen Yung Tien,Huang Der Hua,Lauby Mark G. The Korean Institute of Electrical Engineers 2006 Journal of Electrical Engineering & Technology Vol.1 No.2
Load representation has a significant impact on power system analysis and control results. In this paper, composite load models are developed based on on-line measurement data from a practical power system. Three types of static-dynamic load models are derived: general ZIP-induction motor model, Exponential-induction motor model and Z-induction motor model. For the dynamic induction motor model, two different third-order induction motor models are studied. The performances in modeling real and reactive power behaviors by composite load models are compared with other dynamic load models in terms of relative mismatch error. In addition, numerical consideration of ill-conditioned parameters is addressed based on trajectory sensitivity. Numerical studies indicate that the developed composite load models can accurately capture the dynamic behaviors of loads during disturbance.
Yuan-Hao Chen,Yung-Hsiao Chiang,Hsin-I Ma 대한신경과학회 2014 Journal of Clinical Neurology Vol.10 No.2
Background and Purpose Hypoxia, or ischemia, is a common cause of neurological deficits in the elderly. This study elucidated the mechanisms underlying ischemia-induced brain injury that results in neurological sequelae. Methods Cerebral ischemia was induced in male Sprague-Dawley rats by transient ligationof the left carotid artery followed by 60 min of hypoxia. A two-dimensional differential proteome analysis was performed using matrix-assisted laser desorption ionization-time-of-flightmass spectrometry to compare changes in protein expression on the lesioned side of the cortexrelative to that on the contralateral side at 0, 6, and 24 h after ischemia. Results The expressions of the following five proteins were up-regulated in the ipsilateralcortex at 24 h after ischemia-reperfusion injury compared to the contralateral (i.e., control)side: aconitase 2, neurotensin-related peptide, hypothetical protein XP-212759, 60-kDa heatshock protein, and aldolase A. The expression of one protein, dynamin-1, was up-regulatedonly at the 6-h time point. The level of 78-kDa glucose-regulated protein precursor on the lesioned side of the cerebral cortex was found to be high initially, but then down-regulated by 24 hafter the induction of ischemia-reperfusion injury. The expressions of several metabolic enzymes and translational factors were also perturbed soon after brain ischemia. Conclusions These findings provide insights into the mechanisms underlying the neurodegenerative events that occur following cerebral ischemia.