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Fa-Po Chung,Chin-Yu Lin,Yenn-Jiang Lin,Shih-Lin Chang,Li-Wei Lo,Yu-Feng Hu,Ta-Chuan Tuan,Tze-Fan Chao,Jo-Nan Liao,Ting-Yung Chang,Shih-Ann Chen 대한심장학회 2018 Korean Circulation Journal Vol.48 No.10
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is predominantly an inherited cardiomyopathy with typical histopathological characteristics of fibro-fatty infiltration mainly involving the right ventricular (RV) inflow tract, RV outflow tract, and RV apex in the majority of patients. The above pathologic evolution frequently brings patients with ARVD/C to medical attention owing to the manifestation of syncope, sudden cardiac death (SCD), ventricular arrhythmogenesis, or heart failure. To prevent future or recurrent SCD, an implantable cardiac defibrillator (ICD) is highly desirable in patients with ARVD/C who had experienced unexplained syncope, hemodynamically intolerable ventricular tachycardia (VT), ventricular fibrillation, and/or aborted SCD. Notably, the management of frequent ventricular tachyarrhythmias in ARVD/C is challenging, and the use of antiarrhythmic drugs could be unsatisfactory or limited by the unfavorable side effects. Therefore, radiofrequency catheter ablation (RFCA) has been implemented to treat the drug-refractory VT in ARVD/C for decades. However, the initial understanding of the link between fibro-fatty pathogenesis and ventricular arrhythmogenesis in ARVD/C is scarce, the efficacy and prognosis of endocardial RFCA alone were limited and disappointing. The electrophysiologists had broken through this frontier after better illustration of epicardial substrates and broadly application of epicardial approaches in ARVD/C. In recent works of literature, the application of epicardial ablation also successfully results in higher procedural success and decreases VT recurrences in patients with ARVD/C who are refractory to the endocardial approach during long-term follow-up. In this article, we review the important evolution on the delineation of arrhythmogenic substrates, ablation strategies, and ablation outcome of VT in patients with ARVD/C.
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Customer Knowledge Management--A Case Study of Taiwan's Plastic Industry
Ho, Yung-Ching,Fu, Hsin-Pin,Niu, Chun-Fa,Chien, Pei-Hsiang The Korean Society for Quality Management 2004 The Asian Journal on Quality Vol.5 No.2
This paper investigates customer knowledge management activities of Taiwan's plastic industries. The results demonstrate that the bulk of customer knowledge comes from data related to customer purchase orders and complaints. Furthermore, marketing, production, and research and development are the main departments that developed and reuse customer knowledge. The benefits derived from knowledge management for enterprises do not vary with the position of the vendor on the business scope. In addition, the benefits derived by customers from knowledge management are directly related to the benefits gained by the five major business functions, while the benefits derived from the customer knowledge management are also directly related to customer satisfaction. Summarizing the above results, an Acquisition-Development-Reuse (ADR) model is proposed and can provide the enterprises with a systematic reference model when the business attempts to construct a customer knowledge management system.
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Solving Unbounded Knapsack Problem Using an Adaptive Genetic Algorithm with Elitism Strategy
Rung-Ching Chen,Cheng-Huei Jian,Yung-Fa Huang 보안공학연구지원센터 2008 International Journal of Smart Home Vol.2 No.2
With the popularity of sensor networks, solving the knapsack problem has become important in selecting the best combination of sensor nodes. Many methods have been proposed to solve the Knapsack problem, but few of them have used the genetic algorithm, especially in unbounded Knapsack problems. In this paper, we use the genetic algorithm to solve the unbounded Knapsack problem. We combine an elite strategy and a self adapting system into the genetic algorithm. Using the elite strategy overcomes the problem of the slow convergence rate of the general genetic algorithm. The elite strategy retains good chromosomes and ensures that they are not eliminated through the mechanism of crossover and mutation, ensuring that the features of the offspring chromosomes are at least as good as their parents. The system automatically adapts the number of the initial population of chromosomes and the number of runs to be executed in the genetic algorithm. It will obtain the best value from the chromosomes of each run executed, and retain the values in an elite group. The optimal value is then taken from the elite group and adopted as the real solution. Experimental results have shown that our method rapidly discovers the best solution of the problem.
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Ho Kim, Chan,Jin Lim, Beom,Sung Bae, Yoon,Eun Kwon, Young,Ly Kim, Yung,Heon Nam, Ki,Sook Park, Kyoung,Yeong An, Seong,Mo Koo, Hyang,Mee Doh, Fa,Jung Lee, Mi,Jung Oh, Hyung,Yoo, Tae-Hyun,Kang, Shin-Woo Springer Science and Business Media LLC 2014 Modern pathology Vol.27 No.7
<P>Recently, there has been emerging concern that crescents, the main histologic feature of Henoch-Sch?nlein purpura nephritis, merely reflect active inflammation, and may not be useful in predicting long-term outcomes. We therefore conducted a single-center retrospective study to evaluate whether the new Oxford classification of immunoglobulin A nephropathy can be used to predict long-term outcome in patients with Henoch-Sch?nlein purpura nephritis. We included 61 biopsy-proven patients with Henoch-Sch?nlein purpura nephritis between January 1991 and August 2010. In addition to the International Study of Kidney Disease in Children classification, pathologic findings were also evaluated by the Oxford classification. Primary outcomes were defined as either the onset of estimated glomerular filtration rate <60?ml/min per 1.73?m(2) with 30% decrease in estimated glomerular filtration rate from baseline or end-stage renal disease. During a median follow-up of 49.3 months, 13 (21%) patients reached the primary end point. A Kaplan-Meier plot showed that renal event-free survival was significantly longer in patients with <50% crescents than in those with crescents in 50% of glomeruli (P=0.003). Among the components of the Oxford classification, patients with endocapillary hypercellularity (E1; P=0.016) and tubular atrophy/interstitial fibrosis (T1/T2; P=0.018) had lower renal survival rates than those with E0 and T0. In a multivariate Cox model adjusted for clinical and pathologic factors, E1 (hazard ratio=8.91; 95% confidence interval=1.47-53.88; P=0.017) and T1/T2 (hazard ratio=8.74; 95% confidence interval=1.40-54.38; P=0.020) were independently associated with reaching a primary outcome, whereas the extent of crescentic lesions was not. Our findings suggest that the Oxford classification can be used in predicting long-term outcomes of Henoch-Sch?nlein purpura nephritis.</P>
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Performance of Q-learning based resource allocation for D2D communications in heterogeneous networks
Lee Shu-Hung,Shi Xiao-Pei,Tan Tan-Hsu,Lee Yu-Lin,Huang Yung-Fa 한국통신학회 2023 ICT Express Vol.9 No.6
This study investigates energy efficiency issues of device-to-device (D2D) communications in heterogeneous networks. To minimize the total transmitted power, an approach based on Q-learning together with adaptive ɛ -greedy is proposed to optimize the connection of user equipment (UE) with base station (BS) or access point (AP). The proposed adaptive ɛ -greedy can conduct the adequate exploration and exploitation operations for effective optimization. Simulation results indicate that in the single-cell scenario, the proposed method can attain performance close to the best solution.
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