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      • KCI등재

        완전탈구된 치아의 지연 재석

        한유리,최형준,이제호,최병재 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.4

        완전탈구된 치아의 치료법은 재식술을 들 수 있는데, 이는 치조와에서 이탈된 치아를 가능한 빠른 시간 내에 재식립하는 술식이다. 일반적으로 재식술의 성공여부는 치수와 치주인대 손상의 정도, 치아상실 시부터 치조와 내로 재식될 때까지의 경과시간, 탈구된 치아의 보관 상태, 치근의 발육 정도 등에 좌우된다. 그 중 치아상실 시부터 재식까지의 경과시간이 특히 중요한데, 일반적으로 30분 이내에 재식을 시행한 경우에는 90%이상의 성공률을 보인 반면 30분에서 90분 사이에서는 43%, 90분 이상 경과 시에는 7%의 성공률을 보인다고 알려져 있다. 본 증례는 완전탈구 후 오랜 시간이 지연되어 재식을 시행하였으나 치근유착을 통해 비교적 양호한 임상적 결과를 얻었다. 이러한 치료로 결국은 치아의 손실이 일어날지라도, 이것은 환자 및 보호자의 사고에 따른 충격을 감소시켜주고, 자체로 공간 유지장치로서의 기능을 할 수 있으며, 발치에 따른 치조골의 흡수를 늦추는 한편, 적극적인 보철치료를 위한 시간을 벌어줄 수 있을 것으로 사료된다. Replantation may be treatment choice for a completely avulsed tooth caused by traumatic injury. The outcome of replantation depends on the following factors: minimal damage to pulp and periodontal membrane the length of time the avulsed tooth was out of the mouth, how the tooth was stored the level of root formation, etc. The time from the act of avulsion of the tooth to the actual replantation is especially important. Generally, when replanted within 30 minutes, more than 90% of cases succeed but when the time is between 30 to 90minutes 43% and greater than 90 minutes 7%. This is a case of a replanted tooth with relatively good prognois by ankylosis though there was a great time lapse since the tooth was avulsed. Though such treatment lead to loss of the tooth in case of children or adolescents this treatment is meaningful because it may earn time until any definitive therapy functionally stimulate the alveolar bone to retain its hight for a better prognosis for future treatment and act as space maintainer

      • DeSOx/DeNOx 효율 개선을 위한 펄스 코로나 방전하에서 기체미립자 전환반응의 적용

        김동주,최유리,김교선 江原大學校 産業技術硏究所 1998 産業技術硏究 Vol.18 No.-

        In this paper, we investigated the post-combustion removal of nitrogen oxide(N0?) and sulfur oxide(S0?) which is based on the gas to particle conversion process by the pulsed corona discharge. Under normal pressure, the pulsed corona discharge produces the energetic free electrons which dissociate gas molecules to form the active radicals. These radicals cause the chemical reactions that convert SO? and NO? into acid mists and these mists react with NH? to form solid particles. Those particles can be removed from the gas stream by conventional devices such as electrostatic precipitator or bag filter. The reactor geometry was coaxial with an inner wire discharge electrode and an outer ground electrode wrapped on a glass tube. The simulated flue gas with SO? and NO? by adding NH? and H?O in the gas stream. We also measured the rmoval efficiency of SO? and NO? in a cylinder type corona discharge reactor and obtained more than 90% of removal efficiency in these experimental conditions. The effects of process variables such as the inlet concentrations of SO?, NH? asnd H?O, residence time, pulse frequencies and applied voltages were investigated.

      • KCI등재

        학령전기 아동의 글씨 쓰기에 영향을 미치는 요인에 관한 연구

        김원진,왕군철,김두리,최인영,허진아,최유정,장문영 대한감각통합치료학회 2011 대한감각통합치료학회지 Vol.9 No.1

        목적 : 학령전기 아동의 글씨 쓰기 명료도 및 속도와 지각-운동 기술의 상관관계를 확인하고, 글씨 쓰기에 가장 영 향을 주는 요인을 알아보고자 하였다. 연구방법 : 덴버 발달 선별 검사를 통하여 정상 발달로 선별된 23명의 학령 전기 아동(평균 연령=68.61개월, SD=2.04)을 대상으로 글씨 쓰기 명료도 및 속도 측정을 위하여 한글 자모 쓰기 검사지를 사용하여 자음과 모음을 쓰도록 하였다. 시지각과 시각-운동 통합 수행 능력 측정을 위하여 시지각 발달 검사를 사용하였고, 소운동 협응 수행 능력 측정을 위하여 Grooved pegboard test를 사용하였다. 결과 : 글씨 쓰기 명료도와 전반적인 시지각, 비운동성 시지각, 시각-운동 통합, 우세손 소동작 협응의 상관관계는 없었으며, 글씨 쓰기의 속도는 전반적 시지각과 우세손 소동작 협응 항목에서 유의한 상관관계를 보였다. 회귀 분 석 결과 글씨 쓰기 속도에 가장 큰 영향을 주는 요인은 전반적 시지각 항목이었다. 결론 : 만 5~6세 학령 전기 아동의 전반적 시지각 능력의 발달을 향상시키기 위한 중재를 제공하는 것이 글씨 쓰기 의 속도 능력을 향상 시킬 수 있다는 것을 알 수 있다. Objective : This study investigated the relationships of handwriting legibility and perceptual-motor skills, and handwriting speed and perceptual-motor skills. And identified the predictors that most affect the handwriting of preschool children. Methods : Twenty-three typically developing preschool aged children (mean age: 68.61 months, SD=2.04) were selected through the Korean-Denver Developmental Screening Test-2(K-DDST-2). The children were tested with regard to handwriting legibility, visual perception, visual-motor integration and fine-motor coordination. Results : First, a significant relationship was not found among handwriting legibility, visual perception, visualmotor integration and fine-motor coordination. Second, a significant relationship was found among handwriting speed, visual perception and fine-motor coordination. Third, stepwise multiple regression analyses showed that general visual perception were significant predictors for handwriting speed. Conclusion : Occupational therapists should evaluate children's visual perception levels utilizing a standardized test, and focus on general visual perception in order to improve handwriting skill(speed). Also, occupational therapists are expected to play an important role in the management and treatment of children's handwriting skills.

      • SCISCIESCOPUS

        Fabrication of dihydroxyflavone-conjugated hyaluronic acid nanogels for targeted antitumoral effect

        Choi, Yu Ri,Kim, Hyun-Jong,Ahn, Guk Young,Lee, Min Jeong,Park, Ju Ri,Jun, Dae-Ryong,Ryu, Tae-Kyoung,Park, Joo Woong,Shin, Eunji,Choi, Sung-Wook Elsevier 2018 Colloids and surfaces Biointerfaces Vol.171 No.-

        <P><B>Abstract</B></P> <P>We prepared hyaluronic acid (HA)-based nanogels conjugated with dihydroxyflavone (DHF) and evaluated their cellular uptake and antitumoral efficiency. 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM) was used as a conjugation agent for esterification between DHF and HA as well as crosslinking among HA. The conjugations were confirmed by nuclear magnetic resonance spectroscopy, UV/vis spectroscopy, and high-performance liquid chromatography. The size and Zeta-potential of the DHF/HA nanogels were reduced with an increase in the concentration of DMTMM due to the involvement of more HA molecules for the conjugation reactions. The DHF/HA nanogel with a smaller size was greatly taken up by two kinds of tumor cells (HeLa and HepG2), compared to NIH3T3. The cell viabilities were reduced to approximately 60% for HeLa and HepG2 cells after 48 h post treatment with DHF/HA nanogels.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Hyaluronic acid molecules are conjugated among themselves in nanogel form. </LI> <LI> Dihydroxyflavones are conjugated to hyaluronic acid nanogels. </LI> <LI> A low concentration of a conjugation agent leads to the nanogel size reduction. </LI> <LI> The nanogel specifically reduced the viability of tumor cells to approximately 60%. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • HBV : PE-018 ; Effect of adefovir add-on therapy in chronic hepatitis B patients with antiviral resistance to lamivudine/entecavir sequential therapy

        ( Yu Ri Choi ),( Chun Kyon Lee ),( Jong Won Choi ),( Sun Young Won ),( Jeong Hun Seo ),( Yong Suk Cho ),( Byung Kyu Park ),( June Sung Lee ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

        Background: The efficacy of adefovir add-on therapy in treatment-experienced patients with chronic hepatitis B (CHB) is debatable. This study was aimed to evaluate the efficacy of adefovir add-on therapy in CHB patients with antiviral resistance to lamivudine/entecavir sequential therapy. Methods: CHB patients who exhibited documented resistance to lamivudine and switched to entecavir 1.0 mg monotherapy were evaluated, and 16 patients of them showed active viral replication (HBV DNA levels ≥ 10 copies/mL) or a history of treatment failure to lamivudine/entecavir sequential therapy. Adefovir 10 mg/day has been added to these 16 patients and the virologic parameters were monitored every three months until 72weeks. Results: In the 16 CHB patients, the median age was 53 years. Eight (50.0%) patients was HBeAg positive, 7 (43.8%) was liver cirrhosis, and 9 (56.3%) was liver enzyme elevation (ALT > 40). The median duration of previous entecavir therapy was 84.4±22.5 weeks. The mean HBV DNA level and ALT at baseline were 6.25±0.96 log10 copies/mL, 53±35 IU/mL. At 24, 48, and 72 weeks, the median reduction of the serum HBV DNA level was 2.19±1.34, 3.11±1.41, and 3.18±1.37 log10copies/mL. At 24, 48, and 72 weeks, virologic response (HBV DNA <300 copies) was achived in 18.8 % (3/16), 37.5 % (6/16), and 37.5 % (6/16). At 24, 48, and 72 weeks, biochemical response (ALT <40 IU/mL) was achived in 55.6% (5/9), 66.7% (6/9), and 66.7% (6/9). According to the univariate analysis, initial HBV DNA level was the only independent covariate that was inversely associated with serum HBV DNA negativity at 72 weeks. Conclusions: The adefovir add-on therapy was not efficacious for CHB patients with antiviral resistance to lamivudine/ entecavir sequential therapy. However, viral breakthrough was not seen during the 72 weeks add on therepy.

      • SCIESCOPUSKCI등재

        Impact of Postthyroidectomy Scar on the Quality of Life of Thyroid Cancer Patients

        ( Yu Ri Choi ),( Ji Hye Lee ),( Yeon Hee Kim ),( Yong Sang Lee ),( Hang Seok Chang ),( Cheong Soo Park ),( Mi Ryung Roh ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.6

        Background: Surgical scars are crucial cosmetic problem, especially when in exposed areas such as the anterior neck following thyroidectomy. Objective: To evaluate the impact of post-thyroidectomy scars on quality of life (QoL) of thyroid cancer patients and identify the relationship between scar characteristics and QoL. Methods: Patients with post-thyroidectomy scars on the neck were recruited. QoL was measured using the Dermatology Life Quality Index (DLQI). Scar characteristics were graded according to Vancouver scar scale (VSS) score. Results: Ninety-seven patients completed a battery of questions at the time of enrollment. Post-thyroidectomy scars were classified according to morphology as linear flat scars, linear bulging scars, hypertrophic scars or adhesive scars. There were 32 patients (33.0%), 9 patients (9.3%), 41 patients (42.3%) and 15 patients (15.5%), respectively, in each group. The mean total DLQI score was 9.02. Domain 2 (daily activities, 2.87 points), which includes questions about clothing, was the most greatly impacted among patients. The total DLQI scores of patients who have experienced scar-related symptoms were significantly higher than those of patients without symptoms (p<0.05). The VSS scores were 3.09 for linear flat scars, 6.89 for linear bulging scars, 6.29 for hypertrophic scars and 5.60 for adhesive scars. However, the DLQI scores did not significantly differ among scar types or VSS scores. Conclusion: Post-thyroidectomy scars on the neck affect the QoL of thyroid cancer patients regardless of scar type. Therefore, clinicians should pay attention to the psychological effects of scars on patients and take care to minimize post-thyroidectomy scar. (Ann Dermatol 26(6) 693∼699, 2014)

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