성인의 급성 설사에 대한 로페라미드 옥사이드의 효과: 위약과의 무작위 이중 맹검 비교 다시설 시험

박영태,정희진,박중원,이계희,김나영,임선희,윤병철,한동수,이오영 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.5

터널 변위 거동 및 수치 모의실험의 결합 해석

정윤영 ( Yun Young Jeong ),한희수 ( Heui Soo Han ),이재호 ( Jae Ho Lee ) 대한지질공학회 2010 지질공학 Vol.20 No.1

이 연구는 터널설계의 안정성을 예측하기 위한 터널거동분석에 초점을 맞춘 것이다. 3차원 수치해석, 현장계측 후 최대변형 및 사쿠라이에 의해 제안된 터널변형에 관한 경험적 안정성 평가방법들을 결합한 평가기법을 사용하였다. 사쿠라이가 사용한 계측자료들은 새로운 해석기법을 도입하여 재해석되었다. 터널안정해석을 위한 사쿠라이의 경험적 추세선은 이론적 추세선으로 새로이 도입되었으며, 이는 안정, 불안정 및 파괴영역으로 구분되었다. 터널 현장자료의 새 해석기법을 평가하기 위한 현장의 적용 예로, 김포의 지하철 9호선으로 연결되는 인천공항의 지하철터널을 이용하였다. 그 결과 터널보강후 인천공항 지하철의 상부 및 하부터널 모두 충분한 안정성을 보였다. 마이크로 실리카 그라우팅과 엄브레라방법에 의한 지반보강 후 겉보기 영계수가 상당히 증가하는 것을 볼 수 있었다. 그러므로, 제안된 새 해석기법을 이용하면, 터널변형과 지반조건에 따른 최적의 보강기법 선정에 활용할 수 있다. This study is focused on the analysis of tunnel behavior to estimate the stability on tunnel design. An estimation method was proposed as a hybrid consideration, which contains the displacement analysis by 3D numerical simulation, the maximum displacement obtained after field measurement, and an assessment of tunnel stability using a deformation analysis proposed by Sakurai(1988, 1997). The points of case study by Sakurai(1988, 1997) were replotted considering his analysis. From the new analysis of the tunnel case study, the trend line for analyzed points is analogized, which curve is divided into stable, unstable and failure zone. To evaluate the estimation method, a special shape of railway tunnel was selected, which are the Inchon international airport rail way connected to subway line 9 in Gimpo, Korea. The point s of upper and below track on the Inchon international airport rail way were satisfied to the stability of tunnel after reinforcing. Also the points shows the higher apparent Young`s modulus, which resulted from improvement on shear strength by the micro silica grouting and the supporting of umbrella method. Therefore, if new analysis used, proper tunnel reinforcing method could be selected according to tunnel strain and geological property.

POS를 이용한 레스토랑 관리 시스템의 설계 및 구현

최영민,채민희,정성원,김진일 東義大學校産業技術開發硏究所 2009 産業技術硏究誌 Vol.23 No.-

본 논문에서는 국내의 요식업계 산업이 선진화되고 또한 자동화 시스템이 확대되고 있는 과정에서 요식업계의 한 분야인 레스토랑의 음식 주문을 보다 효과적인 방법으로 주문을 할 수 있는 POS시스템을 개발하는데 목적이 있다. 기존에 사용되고 있는 POS 시스템을 외식업의 한 분야인 레스토랑 관리 시스템에 맞추어 개발하였고 중앙 집중형의 POS 시스템을 사용자 입장에서 나타나는 비효율적인 부분들을 보안하고 편의사항 등을 고려하여 기존 POS 시스템보다 접근하기 쉬운 인터페이스로 구성하였다. 본 논문에서 제안한 레스토랑 관리 시스템 설계는 고객용 주문 프로그램과 마스터 프로그램으로 구분한다. 고객용 주문 프로그램의 카테고리는 음식 메뉴, 선택, 수량, 합계금액을 확인하고 전송할 수 있고 마스터 프로그램의 카테고리는 테이블, 계산, 예약, 재고관리로 구분한다. 이렇게 구분한 카테고리의 정보 인터페이스 기술을 적용하여 최소의 비용으로 고객주문 상태, 계산, 예약 및 재고관리의 효과를 기대한다.

殺蟲性 O,O-Diethylphenylphosphate 誘導體의 形態와 反應性에 關한 分子軌道論的 硏究

朴勝熙,成洛道,明平根,全容求,李天培 충남대학교 약학대학 의약품개발연구소 1985 藥學論文集 Vol.1 No.-

Molecular orbital theoretical study on the stability of conformations and chemical reactivity of 0,0-diethyphenylphosphate derivatives were carried out by EHT and CNDO/2 molecular orbital calculation method. The results shown that the dipole moment(μ) and total energies of the θ=90° conformer were μ=3.185D & E_t=-162.6479(au) and also that of the θ=0° conformer were μ=5.596D & E_t=-162.4013(au), respectively. Therefore, the values of μ & E_t of the θ=90° conformer were much smaller than that of the θ=0° conformer. The form with angle of rotation θ=90° of phenyl ring was shown to be most stable and this was interpreted in terms of electrostatic and steric effect. O,O-diethylphenylphosphate derivatives are predicted to increase both charge and orbital controlled SN_2 reactivity of the electron withdrawing substituent reduces the HOMO & LUMO energy, while the electron withdrawing substituent due to increase in positive charge of phosphorus atom of phosphate molecule.

금속 대 금속 고관절 전치환술 후 혈청 및 소변 코발트와 크롬 수치 중간 결과보고(5~10년)

김영창,곽희철 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Introduction : The purpose of this study is to evaluate the midterm(minimum 5years) results of THR with 2nd generation Metal on Metal prosthesis. Materials and Methods : The (52patients)60case of THR with End generation Metal on Metal prostheses was evaluated after an average duration of follow up of 784 months. The age of the patients at the time of operation had twenty five to seventy four years(average 54.7 years). Men was 33patients, women was 19patients. Preoperatively diagnosis was avascular necrosis 36case, osteoarthritis 18case, hip fracture 3case, ankylosing spondylitis 2case, tuberculosis 1case. Postoperative follow up was 6month, 1year 2year, 3year, 4year and last follow up. Physical examination, blood and urine was collected that were calculated by Atomic absorption spectroph otometry. Results : Harris hip score, Co-Cr concentration was evaluated. Harris hip score improved from 49.3point to 93.2point. Although Co-Cr concentration were elevated, but clinically definite toxicity was not detect. Conclusion : Conclusively the midterm(minimum 5years) results of THR with 2nd generation Metal on Metal prosthesis were excellent. Co-Cr concentration were elevated, but not detect continuous accumulation within body and definite toxicity. We need further long term evaluation of metal effect on human body.

Fe-20Cr-xNi-6Mo-0.3N계 스테인리스강의 부식 특성에 미치는 Ni의 영향

김영식,박인규,김태희 안동대학교 기초과학연구소 1992 基礎科學 硏究論文集 Vol.3 No.1

염산과 황산 용액 중에서 나타나는 Fe-20Cr-xNi-6Mo-0.3N계 스테인리스강의 부식 특성에 미치는 니켈 함량의 영향을 구명하기 위하여 양극 분극 시험, 재부동태화 시험 및 용액 분석을 행하였다. 니켈 함량이 증가할수록 부식 전위는 상승하였으나, 임계 전류 밀도와 부동태 전류밀도는 각각 시험 용액에 따라 다르게 나타났다. 본 연구에서는 이러한 부동태화 거동에 미치는 니켈 함량의 영향에 대하여 평가하고 검토하였다. The effect of nickel content on the corrosion properties of Fe-20Cr-xNi-6Mo-0.3N stainless steels in a hydrochloric acid and a sulfuric acid has been studied by anodic polarization test, repassivation test, and solution analysis. With an increase in the nickel content, it was found that the corrosion potential was increased, but the critical current density and the passive current density were depended on test solutions. In this work, the effect of nickel content on the passivation behavior was evaluated and discussed as well.

韓國 看護大學 敎育課程에 對한 硏究

文姬子,金潤喜,趙潔子,趙美映,姜賢淑 慶熙大學校 1982 論文集 Vol.11 No.-

The changes of social issues and nursing concepts require the expansion of nursing needs and nursing role, therefore it is keenly demanded the necessity of the research for new curriculum development in nursing. So to make a contribution to the development of nursing education in Korea, we made a comparative study of nursing curriculum of each universities which have baccalaureate program and put them into operation at present; they are 10 Korean universities, 5 American universities and 4 Japanese Universities. Thus by researching the differences among them. We acquired the conclusions as followings. The purpose of Nursing education In case of Korean parts, the contents of those aims must be explained more clearly and more in detail than another results of research. There also has to be made the statements upon the scientific researching methodology in scholarly respect, or the self-development in individual respect, or the lasting endeavour for studies in professional respect. We must put an emphasis upon the statement and education of the direct nursing provider, or the primary health care manager at hospital and community, who is one of the important aims of modern nursing education. The substance of nursing curriculum. 1) Total credits for completion and the comparison of curriculums, classified by the field. The scope of total credits of each nation, according to Colleges ranges; Korea: 140-163, U.S.A.: 121-187, Japan: 13-158 Compared with those of U.S.A. and Japan, the average credits of Korea is higher. Classified by the field, the credits alloted to major courses are 73.3% and liberal courses, only 26%, which shows that it does not satisfy the current educational trend that emphasizes the liberal course. 2) The comparison of curriculums, classified by a school year. In case of Korea, the total credits are evenly assigned to all grades, but the freshman taken the concentration of liberal courses (81.2%). Among the major courses are preponderant the Nursing Supportive subjects in the sophomore and the nursing major ones in the junior and senior. 3) Curriculums classified by the subject. (1) As compared with those of Japan and U.S.A. Korean students are less free in chosing subjects their own way all over the curriculums. It is, therefore, required that the range of the optionals be widened for the open and flexible education. (2) We can find all of three nations (Korea, Japan, U.S.A.) neglect the sphere of the behavioral sciences among the fundamental nursing subjects. In the field of social sciences, among Korea, Japan, and U.S.A., top ranks Japan that tends of the interested in social well-being. In Korea only two universities have this subjects. (3) Nursing major subjects. Defficulties in comparing them lie in the gulfs of the title of subjects, and the structural differences of the formation of curriculums among nations. In case of Korea, although there are a few differences of the number of credit of subjects among colleges, she has uniform aspects for U.S.A., which says that there are no characteristics and self-control each colleges has in Korea. We can notice that the subjects each Korean university shares are also doubled with those of the national examination for nursing qualification. Japan differs from Korea in that subjects are more differentiated and students are provided with more chances to make a choice through the system of subjects and the texture of a curriculum are similar to those of Korea. In case of Korea, therefore, the unification of fundamental subjects (especially in the medical field) and clinical practices is required. (4) The course for teaching profession is taken as either the required or optional just in Korea (80%) and Japan (75%). The number of subjects and total credits of teaching courses is different according to the colleges of Korea and Japan. As for the contents of subjects Korea deals with theory and Japan, the practical thing with which students can adjust themselves to the spot of society. As a result of that, in case of Korea, demanded are the entire review and research upon the purpose of establishing a curriculum, its relation to the total credits and the choice of substance of subjects etc. 4) The patterns of organization in curriculum development. Most of the patterns of organization, classified by clinic subject pivot upon disease and subjests are not mutually unified in case of Korea and Japan. Though the patterns of organization of subjects if formally unified, that of curriculums is not substantially or wholy synthesized, while in case of U.S.A. the unification of the patterns of organization entire curriculum as well as the mutual unification of subjects is attained and each college runs a characteristic curriculum, since the application of nursing theory and the model of a curriculum are different according to college. The prevention of disease, the promoting health and the disease system is patterned, centering around the healthy and their families. Therefore, in case of Korea, it is urgent to unify the curriculum of nursing education for the efficiency of the future oriented nursing education, and it is also imminent to develop the new pattern of a nursing curriculum suited for our own social demand and situation. And we need the continuous studies and search for the method of application in order to development the new curriculum. The comparison of a curriculum with the purpose of nursing education. The substances of subjects are not consistently in accord with the aims of nursing education each college states in Korea, Japan and U.S.A. Especially in case of Korea, the most statements upon the purpose of education are in the social dimension, but the most subjects have the academic dimension. In Korea it is stringent to examine and study the choice of the contents of education in terms of learning, profession, individual and society.

다짐함수비 變化에 따른 필댐의 擧動分析

임희대,김태곤,이영섭,고근식 충남대학교 산업기술연구소 1999 산업기술연구논문집 Vol.14 No.2

Compaction water content is a key variable which controls fundamental properties of compacted clay (permeability, deformation and strength). There are three conditions in compaction water content (i.e. dry of optimum, optimum and wet of optimum). Actually, soil mass by compaction is unsaturated condition before seepage therefore, soil suction is the key which is able to explain properties of compacted clay. This paper used results from compacted Pittsburg sandy clay tested under UU test condition from Duncan and Seed in order to determine hyperbolic parameters and simulated behavior of Soyanggang dam as a example. As the results of analysis, dry of optimum presents higher strength and smaller displacement. Wet of optimum is sensitive to water content. Both dry and wet of optimum, any hydraulic fracturing potential does not appear. But dry of optimum is close to hydraulic fracturing.

세균속간 시데로포아 생산능의 비교에 Chrome azurol S 한천배지 확산법의 응용

배영훈,박라영,신성희 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

연구배경 : 세균이 생산하는 시데로포아를 정량적으로 측정하기 위한 새로운 측정법인 chrome azurol S 한천배지 확산법(CASAD)이 저자들에 의해 개발되었다. 본 연구에서는 이 CASAD 법이 세균속간 시데로포아 생산을 비교하는 데에도 사용될 수 있는지를 알아보고자 하였다. 방법: Staphvlococcus aureus, Staphylococcus eptdermidis, Bacillus cereus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Vibrio vulnificus 균을 철을 제거한배지에 트렌스페린을 철공급원으로 공급한 배지에서 배양하면서 세균들의 증식은 파장 600 nm에서 흡광도를 측정하여 관찰하고 시데로포아 생산능은 CASAD법을 이용하여 관찰하였다. 트렌스페린으로부터 철을 획득하는 능력을비교하기 위하여 6 M urea를 함유하는 전기영동법을 사용하였다. 결과: 세균속간 시데로포아 생산능에는 큰 차이가 있었다. S. aureus, S. epidermidis, E. coli, P. aeruginosa는 B. cereus, B. subtilis, V. vulnificus체 비해 더 많은 양의 시데로포아를 생산할 수 있었고 트렌스페린으로부터 철을 더 효율적으로 획득할 수 있었으며 트렌스페린이 첨가된 배지에서 더 잘 자랄 수 있었다. 시데로포아 생산능과 트렌스페린으로부터 철을 획득하는 능력에는 밀접한 상관관계가 있었다. 결론: 본 연구를 통해 저자들은 CASAD법이 세균속간 시데로포아 생산능을 비교하는데에도 유용하게 사용될 수 있음을 알 수 있었다. Background: We recently developed a new chrome azurol S agar diffusion (CASAD) assay for the quantitative analysis of siderophore production. This study was designed to evaluate the usefulness of the CASAD assay for the comparison of the ability to produce siderophore among different genera of bacteria. Materials and Methods: Strains of Staphy lococctis aureus, Staphylococcus epidermidis, Bacillus cereus, Bacilhis subtilis, Escherichia coli, Pseudomonas aeruginosa, and Vibrio vulniftctis were used. The bacteria were cultured in deferrated heart infusion broth containing transferrin at 37℃ for 24 hours. During the cultures, Bacterial growth was measured by OD_(600), siderophore production was measured by CASAD assay, and iron-removal from transferrin was measured by 6 M urea-gel electrophoresis. Results: There was a big difference in the ability of the bacteria to produce siderophores. S. aureus, S. epidermidis, E. coli, and P. aeruginosa produced larger amounts of siderophores than B. cereus, B. subtilis, and V. vulnificus. S. aureus. S. epidermidis, E. coli, and P. aeruginosa utilized more efficiently transferrin-bound iron than B. cereus, B. subtilis, and V. vulnificus. The ability of the bacteria to produce siderophores was consistent with the ability of the bacteria to grow on transferrin-bound iron and to uptake iron from human transferrin. Conclusion: Through this study, we found that the CASAD assay is a useful universal method that can be applied for the intergeneric comparison of the ability to produce siderophores.

2세대 Metal-on-Metal Prosthesis를 사용한무시멘트 인공 고관절 전치환술 중간 결과 보고 (5-10년)

김영창,정경칠,곽희철,김주용 대한고관절학회 2004 Hip and Pelvis Vol.16 No.1