교류분석 이론에 근거한 드라이버와 시간구조화 척도 타당성 연구 : Study on the Validation of Driver Scale and Time Structuring Scale

문호영(Ho Young, Moon),윤영진(Young Jin, Yun) 한국교류분석상담학회 2021 교류분석상담연구 Vol.11 No.1

본 연구의 목적은 교류분석 이론에 근거한 성인용 드라이버와 시간구조화 척도를 개발하고 타당성을 검증하는 것이다. 연구 대상은 성인 1,671명(남 594명, 여 1,067명)으로 1차(2018년)와 2차(2019년) 두 차례의 연구로 진행되었다. 1차 연구는 드라이버 척도 64문항(완벽하게 하라 12문항, 남을 기쁘게 하라 12문항, 서둘러라 12문항, 열심히 하라 14문항, 강해져라 14문항), 시간구조화 척도 71문항(폐쇄 14문항, 의식 14문항, 활동 10문항, 잡담 13문항, 게임 10문항, 친밀 10)에 대해 타당성을 검증하여 신뢰로운 문항을 선정하는 것이었다. 2차 연구는 1차 연구분석 결과 선정된 드라이버 척도 45문항(5요인 각 9문항), 시간구조화 척도 48문항(6요인 각 8문항)에 대한 타당성 검증과정을 거쳐 드라이버와 시간구조화 척도를 표준화하는 것이었다. 연구 결과를 보면, 개발된 드라이버 45문항과 시간구조화 48문항 모두 신뢰롭고 타당도가 높은 문항임이 확인되었다. 본 연구에서 개발된 두 척도는 급속한 성장을 이룬 한국사회 성인의 병리적 현상과 특성을 이해하는데 유용할 것으로 판단된다. 또한 드라이버와 시간구조화 척도는 심리특성 진단, 학교 교육, 기업 등 다양한 분야에서 진단도구로 활용될 수 있다는 점에서 그 의의가 있다고 할 수 있다. The purpose of this study is re-validate the validation of the Driver Scale and Time Structuring Scale devised by Moon, ho- young in 2017. This study is carried out two times with 1671 people - 1021 adults at first time and 650 at the other. The first study included 50 questions on driver scale devised by Moon, ho- young and 64 questions that added 14 questions: two questions on ‘Be perfect’, two on ‘Please others’, two on ‘Hurry up’, four on ‘Try hard’, four on ‘Be strong.’71 questions regarding on time structuring scale were studied in detail as the following: 11 questions were added to the 60 basic questions and the 11 questions were consisted of four questions on ‘Withdrawal’, four on ‘Rituals’, and three questions on ‘Pastimes’. The writers select highly valid and trustworthy questions using various method of analysis. The second study was conducted to validate the validation of the scale with 45 questions on drive scale and 48 questions on time structuring scale that were chosen from the first study result. Through these two studies researchers completed the Korean driver scale and time structuring scale. The result of this study clearly shows that 45 questions on driver scale questions and 48 questions on time structuring scale devised by Moon, ho- young(2017) including some modified questions and one newly invented question were highly valid and trustworthy in evaluating the validity of each scale. This result of this study proves that the driver scale and time structuring scale devised by Moon, ho-young(2017) is a valid tool for testing Korean adults.

Morin exerts cytoprotective effects against oxidative stress in C2C12 myoblasts via the upregulation of Nrf2-dependent HO-1 expression and the activation of the ERK pathway

Lee, Moon Hee,Han, Min Ho,Lee, Dae-Sung,Park, Cheol,Hong, Su-Hyun,Kim, Gi-Young,Hong, Sang Hoon,Song, Kyoung Seob,Choi, Il-Whan,Cha, Hee-Jae,Choi, Yung Hyun UNKNOWN 2017 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.39 No.2

<P>In the present study, we investigated the cytoprotective efficacy of morin, a natural flavonoid, against oxidative stress and elucidated the underlying mechanisms in C2C12 myoblasts. Our results indicated that morin treatment prior to hydrogen peroxide (H2O2) exposure significantly increased cell viability and prevented the generation of reactive oxygen species. H2O2-induced comet-like DNA formation and gamma H2AX phosphorylation were also markedly suppressed by morin with a parallel inhibition of apoptosis in C2C12 myoblasts, suggesting that morin prevented H2O2-induced cellular DNA damage. Furthermore, morin markedly enhanced the expression of heme oxygenase-1 (HO-1) associated with the induction and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the inhibition of Kelch-like ECH-associated protein 1 (Keapl) expression. Notably, these events were eliminated by transient transfection with Nrf2-specific small interfering RNA. Additional experiments demonstrated that the activation of the Nrf2/HO-1 pathway by morin was mediated by the extracellular signal-regulated kinase (ERK) signaling cascade. This phenomenon was confirmed with suppressed Nrf2 phosphorylation and consequently diminished HO-1 expression in cells treated with a pharmacological inhibitor of ERK. Collectively, these results demonstrated that morin augments the cellular antioxidant defense capacity through the activation of Nrf2/HO-1 signaling, which involves the activation of the ERK pathway, thereby protecting C2C12 myoblasts from H2O2,-induced oxidative cytotoxicity.</P>

Antioxidant and cytoprotective effects of morin against hydrogen peroxide-induced oxidative stress are associated with the induction of Nrf-2-mediated HO-1 expression in V79-4 Chinese hamster lung fibroblasts

Lee, Moon Hee,Cha, Hee-Jae,Choi, Eun Ok,Han, Min Ho,Kim, Sung Ok,Kim, Gi-Young,Hong, Su Hyun,Park, Cheol,Moon, Sung-Kwon,Jeong, Soon-Jeong,Jeong, Moon-Jin,Kim, Wun-Jae,Choi, Yung Hyun Spandidos Publications 2017 International journal of molecular medicine Vol.39 No.3

<P>Natural phytochemicals of plant origin, including flavonoids, have been found to be potent antioxidants providing beneficial effects against oxidative stress-related diseases. The present study was carried out to investigate the antioxidant properties of morin, a flavonoid originally isolated from the flowering plants of the Moraceae family. Superoxide dismutase (SOD)-like activity and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(center dot+)) radical scavenging activity were determined. We also investigated the cytoprotective effects of morin against hydrogen peroxide (H2O2)-induced DNA damage and apoptosis in V79-4 Chinese hamster lung fibroblasts. Our results demonstrated that morin had strong scavenging effects against ABTS' radicals with enhanced SOD activity, which varied in a dose-dependent manner. Morin was found to reduce H2O2-induced intracellular reactive oxygen species generation and nuclear DNA damage, and it recovered cell viability damaged by H2O2 via inhibition of mitochondrial dysfunction-mediated apoptosis. Notably, the treatment of V79-4 cells with morin markedly enhanced the expression of heme oxygenase-1 (HO-1) but not quinone oxidoreductase-1, which was associated with the increased expression and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the downregulation of Kelch-like ECH-associated protein 1 expression. Based on our findings, we conclude that morin effectively ameliorated oxidative stress-induced DNA damage through intrinsic free radical scavenging activity and activation of the Nrf2/HO-1 pathway.</P>

QR코드를 이용한 청소년 체험학습 쿠폰 시스템 개발

박순호 ( Soon Ho Park ),김유두 ( Yu Doo Kim ),문일영 ( Il Young Moon ) 한국실천공학교육학회 2013 실천공학교육논문지 Vol.5 No.1

PC의 빠른 보급으로 많은 사용자가 PC로 다양한 콘텐츠를 즐기고 있다. 특히 최근 들어 청소년들의 PC이용 률이 급격히 증가했다. 청소년들은 이러한 PC를 이용하여 보다 쉽게 정보를 얻을 수 있고, 특히 온라인 게임을 통하여 스트레스를 해소하고, 가상현실에서의 또 다른 재미를 느낄 수 있다. 이렇게 일찍부터 빠르게 발전하고 있는 IT문화를 접하는 것은 좋은 일인 것은 분명하다. 하지만 그로 인해 청소년들은 자연스럽게 실내 활동이 많아지게 되면서 야외활동이 줄어들게 됨에 따라 세상을 보는 시야 또한 많이 좁아지게 되었다. 따라서 청소년 들의 야외활동을 유도하기 위해 최근 많이 사용하는 스마트 폰 어플리케이션을 이용하여 현장체험 쿠폰 시스템을 구축하게 되었다. 그리고 HTML5를 기반으로 하는 하이브리드 앱을 개발함으로써 디바이스의 구분없이 사용할 수 있도록 하였다. 따라서 이 어플리케이션을 통해서 청소년들의 현장체험에 대한 관심과 동기를 유발시킴으로써 많은 볼거리를 체험하고, 다양한 시각에서 세상을 바라볼 수 있다. Because of rapid spread of the PC, many users have been enjoying a variety of content as PC. Especially in recent years, young people has increased dramatically PC usage. Young people get more easily information using a PC. Especially they relieve their stress through online games and feel another fun of virtual reality. It is obviously a good effect that they contact IT culture with rapidly developed. But young people`s perspective with world is narrow because of doing more indoor activities than outdoor. Therefore we built Spot experience voucher system using smart phone application. We hope that many young people act outdoor activities. And Our product offer hybrid device by developing HTML5-based app. Thus this app will give interest of spot-experience to young-people. So If young people use this app, they can have many experience and see diverse aspects.

Protective Effect of Heme Oxygenase-1 on High Glucose-Induced Pancreatic β-Cell Injury

Lee, Eun-Mi,Lee, Young-Eun,Lee, Esder,Ryu, Gyeong Ryul,Ko, Seung-Hyun,Moon, Sung-Dae,Song, Ki-Ho,Ahn, Yu-Bae Korean Diabetes Association 2011 Diabetes and Metabolism Journal Vol.35 No.5

<P><B>Background</B></P><P>Glucose toxicity that is caused by chronic exposure to a high glucose concentration leads to islet dysfunction and induces apoptosis in pancreatic β-cells. Heme oxygenase-1 (HO-1) has been identified as an anti-apoptotic and cytoprotective gene. The purpose of this study is to investigate whether HO-1 up-regulation when using metalloprotophyrin (cobalt protoporphyrin, CoPP) could protect pancreatic β-cells from high glucose-induced apoptosis.</P><P><B>Methods</B></P><P>Reverse transcription-polymerase chain reaction was performed to analyze the CoPP-induced mRNA expression of HO-1. Cell viability of INS-1 cells cultured in the presence of CoPP was examined by acridine orange/propidium iodide staining. The generation of intracellular reactive oxygen species (ROS) was measured using flow cytometry. Glucose stimulated insulin secretion (GSIS) was determined following incubation with CoPP in different glucose concentrations.</P><P><B>Results</B></P><P>CoPP increased HO-1 mRNA expression in both a dose- and time-dependent manner. Overexpression of HO-1 inhibited caspase-3, and the number of dead cells in the presence of CoPP was significantly decreased when exposed to high glucose conditions (HG). CoPP also decreased the generation of intracellular ROS by 50% during 72 hours of culture with HG. However, decreased GSIS was not recovered even in the presence of CoPP.</P><P><B>Conclusion</B></P><P>Our data suggest that CoPP-induced HO-1 up-regulation results in protection from high glucose-induced apoptosis in INS-1 cells; however, glucose stimulated insulin secretion is not restored.</P>

디지털 영상인식 방법을 통한 자세평가 및 운동가동범위 측정시스템 개발

문영진,이순호,백진호,이종각,이건범 한국운동역학회 2004 한국운동역학회지 Vol.14 No.3

Y. J. MOON, S. H. LEE, J. H. BACK, J. K, LEE, K. B. LEE. The development of posture evaluation and Range of Motion(ROM) system by using digital vision analysis method. Korean Journal of Sport Biomechanics, Vol. 14, No. 3, pp. 49-65, 2004. The purpose of this study is development of posture evaluation and Range of Motion(ROM) system by using digital vision analysis method. The results of this study are as follows. First, Scoliosis evaluation through this research measurement system represent 3mm error in 7 cervical point and deepest lumbar point, 0.7mm error in other point. This mean this research measurement system have a reliability for scoliosis evaluation. Second, for spine line evaluation on high fat subject, we need reconstrection spine line after mesurement for fat thickness in 7 cervical point and deepest lumbar point. Third, In pedioscope error test, it present 0.01848cm in X axis and 0.01757cm in Y axis. This results mean pedioscope have a reliability foot evaluation. Forth, Posture evaluation and Range of Motion measurement system by using digital vision analysis method can fast measure in range of motion and foot evaluation and posture. therefore we can expect this system application in young people posture clinic center and hospital and so on.

Korea Pathfinder Lunar Orbiter (KPLO) Operation: From Design to Initial Results

Moon-Jin Jeon,Young-Ho Cho,김은혁,Dong-Gyu Kim,Young-Joo Song,홍승범,Jonghee Bae,Jun Bang,Jo Ryeong Yim,Dae-Kwan Kim 한국우주과학회 2024 Journal of Astronomy and Space Sciences Vol.41 No.1

Korea Pathfinder Lunar Orbiter (KPLO) is South Korea’s first space exploration mission, developed by the Korea Aerospace Research Institute. It aims to develop technologies for lunar exploration, explore lunar science, and test new technologies. KPLO was launched on August 5, 2022, by a Falcon-9 launch vehicle from cape canaveral space force station (CCSFS) in the United States and placed on a ballistic lunar transfer (BLT) trajectory. A total of four trajectory correction maneuvers were performed during the approximately 4.5-month trans-lunar cruise phase to reach the Moon. Starting with the first lunar orbit insertion (LOI) maneuver on December 16, the spacecraft performed a total of three maneuvers before arriving at the lunar mission orbit, at an altitude of 100 kilometers, on December 27, 2022. After entering lunar orbit, the commissioning phase validated the operation of the mission mode, in which the payload is oriented toward the center of the Moon. After completing about one month of commissioning, normal mission operations began, and each payload successfully performed its planned mission. All of the spacecraft operations that KPLO performs from launch to normal operations were designed through the system operations design process. This includes operations that are automatically initiated post-separation from the launch vehicle, as well as those in lunar transfer orbit and lunar mission orbit. Key operational procedures such as the spacecraft’s initial checkout, trajectory correction maneuvers, LOI, and commissioning were developed during the early operation preparation phase. These procedures were executed effectively during both the early and normal operation phases. The successful execution of these operations confirms the robust verification of the system operation.

개의 상후두신경 뇌간유발반응에 대한 실험적 연구

김광문,김영호,김광문,김영호 대한이비인후과학회 1998 대한이비인후과학회지 두경부외과학 Vol.41 No.4

남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

Ethylenediaminetetraacetic acid(EDTA)항응고제에 의한 Mean Corpuscular Volume(MCV)변화

홍승민,박영진,최하영,임진,정옥연,이호준,이호영,장숙진,문대수 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.2

It is essential that we put the anticoagulant into the blood specimen of the CBC test. However, the value of some parameters in the CBC test can be changed whenever using some anticoagulants. EDTA anticoagulant is mostly used these days. There are 3 kinds of EDTA, that is K_(2-), K_(3-), and Na_(2-) EDTA. The author studies how many effects each the EDTA gets into the true value of blood specimen for MCV of RBCs. Especially we compared the MCV effect of different concentrations of 3 EDTA anticoagulants on the bias with time and instrument. Some results are gotten. In our results, K_(3-)EDTA anticoagulant shows more satisfactory MCV value than K_(2) or Na_(2-)EDTA. On using concentration of EDTA, 1.5㎎ EDTA/㎖ of blood show more satisfactory MCV value than 7.5㎎ EDTA/㎖ of blood. However, the choice of anticoagulant may be dependant on the different instruments.