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( Hwa Mok Kim ),( Bum Soo Kim ),( Yong Kyun Cho ),( Byung Lk Kim ),( Chong Il Sohn ),( Woo Kyun Jeon ),( Hong Joo Kim ),( Dong Il Park ),( Jung Ho Park ),( Kwan Joong Joo ),( Chang Joon Kim ),( Yong S 대한간학회 2013 Clinical and Molecular Hepatology(대한간학회지) Vol.19 No.3
Background/Aims: The red-blood-cell distribution width (RDW) is a newly recognized risk marker in patients with cardiovascular disease, but its role in nonalcoholic fatty liver disease (NAFLD) has not been well defined. The aim of the present study was to determine the association between RDW values and the level of fibrosis in NAFLD according to BARD and FIB-4 scores. Methods: This study included 24,547 subjects who had been diagnosed with NAFLD based on abdominal ultrasonography and questionnaires about alcohol consumption. The degree of liver fibrosis was determined according to BARD and FIB-4 scores. The association between RDW values and the degree of fibrosis in NAFLD was analyzed retrospectively. Results: After adjusting for age, hemoglobin level, mean corpuscular volume, history of hypertension, history of diabetes, and high-sensitivity (-reactive protein, the RDW values were 12.61±0.41% (mean±SD), 12.70±0.70%, 12.77±0.62%, 12.87±0.82%, and 13.25±0.90% for those with BARD scores of 0, 1, 2, 3, and 4, respectively, and 12.71±0.72%, 12.79±0.66%, and 13.23±1.52% for those with FIB-4 scores of <1.30, 1.31-2.66, and ~2.67, respectively (P<0.05). The prevalence of advanced fibrosis (BARD score of 24 and FIB-4 score of ~1.3) increased with the RDW [BARD score: 51.1% in quartile 1 (Q1) vs. 63.6% in Q4; FIB-4 score: 6.9% in Q1 vs. 10.5% in Q4; P<O.OOl]. After adjustments, the odds ratio of having advanced fibrosis for those in Q4 compared to Q1 were 1.76 (95%(1=1.55-2.00, P<O.OOl) relative to BARD score and 1.69 (95%(1=1.52-1.98, P<O.OOl) relative to FIB-4 score. Conclusions: Elevated RDW is independently associated with advanced fibrosis in NAFLD. (Clin Mol Hepatol 2013;19:258-265)
수치모형실험을 통한 콘크리트 구조물의 결함탐지에 관한 연구
김용인(Kim Yong In),변중무(Byun Joong Moo),손권익(Sohn Kwon lk),서백수(Suh Baek Soo) 강원대학교 산업기술연구소 2004 産業技術硏究 Vol.24 No.1
In this study, First, the results of travel-time inversion (first arrival inversion using the travel-time of the first arrival) were compared with those of full-wave inversion for numerical data. Numerical experiments to find key parameters other than initial velocity model showed that the frequency of source has a great effect on the result of full-wave inversion. Finally, this research presented the corrected full-wave inversion applying the correction term to the final result of full-wave inversion. The corrected full-wave inversion depicted cavities inside concretes even when the inversion started with 20% error in an initial velocity model for cavities. However, full-wave inversion did not reveal cavities.