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JunCheng Guo,YiJun Yang,Min Guo,XiaoDan Wang,Yang Juan,YunSuo Gao,LinQiu Fu,XiangLing Jiang,LinMei Fu,Tao Huang 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.4
Objective-To investigate the correlations of four genetic single nucleotide polymorphisms (SNPs) of brain-derived neurotrophic factor (BDNF) with posttraumatic stress disorder (PTSD). Methods-A total of 300 patients with sporadic PTSD and 150 healthy subjects (the control group) were selected according to the diagnostic criteria of PTSD (DSM-IV), and the genotypes of the BDNF SNPs G-712A, C270T, rs6265, and rs7103411 were detected by polymerase chain reaction and direct DNA sequencing to determine intergroup differences in the genotypes and allele frequencies; the pvalues were corrected with the permutation test. Results-The genotypes and allele frequencies of the SNPs G-712A, rs6265, and rs7103411 of BDNF showed no significant intergroup differences (p>0.05). However, the genotype and allele frequencies of C270T showed significant differences between the PTSD group and the control group (p<0.05). Conclusion-The SNP C270T of BDNF may be associated with PTSD. Individuals carrying the polymorphic T allele of C270T may be more likely to suffer from PTSD.
Yan Ge,Jiapeng Tang,Haihong Fu,Yijun Fu,Yuan-Yuan Wu 한국섬유공학회 2019 Fibers and polymers Vol.20 No.4
In this paper, a notable chitosan/poly(ethylene oxide) nanofiber mats containing tea tree oil liposomes (TOLCENs)were successfully fabricated using electrospinning process. The microstructures and morphology were characterizedby scanning electron microscopy. The porosity, fluid absorbability, water vapor permeability and mechanical properties ofnanofiber mats were also estimated by ethanol density method, gravimetric method, dish method and tensile test,respectively. Compared to the chitosan/poly(ethylene oxide) composite freeze-dried sponges containing tea tree oilliposomes, TOL-CENs had greater porosity, water absorption, breathability and better mechanical properties. In addition, thecontrolled-release properties and long-term bactericidal capability of the material were also assessed. From the analysis of therelease kinetics and mechanism, it was found that the significant decreased terpinen-4-ol concentration gradient fromliposomal surface to the outside of material was the key to the sustained terpinen-4-ol release in virtue of liposomalencapsulation. TOL-CENs exhibited long-term and more excellent microbicidal effects against Staphylococcus aureus,Escherichia coli and Candida albicans than chitosan/poly(ethylene oxide) nanofiber mats. The combination of tea tree oilliposomes and chitosan in nanofiber mats synergistically destroyed cell membrane, prevented cell adhesion and caused theirregular aggregation of cytoplasm, resulting in cell disintegration observed by transmission electron microscope. Insummary, TOL-CENs had potential application value as a long-term antimicrobial nonwoven materials.
Enhancement mechanism of SO2 removal with calcium hydroxide in the presence of NO2
Jihui Gao,Guoqing Chen,Xiaolin Fu,Yijun Yin,Shaohua Wu,Yukun Qin 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.2
The enhancement mechanism of SO2 removal by the presence of NO2 under low temperature and humid conditions was studied in a fixed bed reactor system. The presence of NO2 in the flue gas can enhance SO2 removal. The interaction between SO2 and NO2 in gas phase could not explain the effect of NO2 on SO2 removal under lowtemperature and humid conditions. When Ca(NO3)2 and Ca(NO2)2 as additive were added on the surface of sorbent,the desulfurization activity of sorbent decreased. However, the sorbent pretreated by NO2 for a moment has higher SO2removal. The oxidization of SO32− to SO42− and the evolution of sorbent surface structure in the presence of NO2 can explain the enhancement of SO2 removal by the presence of NO2. HSO3− and SO3− reacted with NO2 to form sulfate,which can accelerate the hydrolysis of SO2. The reaction between NO2 and Ca(OH)2 can make the unreacted sorbet under the SO2 removal product exposed to the reactant gas.