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RISS 인기검색어
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- 저자 : Yi-Qun Song (검색결과 4 건)
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Influence of Curcumin on HOTAIR-Mediated Migration of Human Renal Cell Carcinoma Cells
Pei, Chang-Song,Wu, Hong-Yan,Fan, Fan-Tian,Wu, Yi,Shen, Cun-Si,Pan, Li-Qun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10
Background: This study investigated the influence of curcumin on HOX transcript antisense RNA (HOTAIR)-mediated migration of cultured renal cell carcinoma (RCC) cells. Materials and Methods: Five RCC cell lines (769-P, 769-P-vector, 769-P-HOTAIR, 786-0, and Kert-3 ) were maintained in vitro. The expression of HOTAIR mRNA was determined by quantitative real-time PCR and cell migration was measured by transwell migration assay. The effects of different concentrations of curcumin (0 to $80{\mu}mol/L$) on cell proliferation was determined by the CCK-8 assay and influence of non-toxic levels (0 to $10{\mu}M$) on the migration of RCC cells was also determined. Results: Comparison of the 5 cell lines indicated a correlation between HOTAIR mRNA expression and cell migration. In particular, the migration of 769-P-HOTAIR cells was significantly higher than that of 769-P-vector cells. Curcumin at $2.5-10{\mu}M$ had no evident toxicity against RCC cells, but inhibited cell migration in a concentration-dependent manner. Conclusions: HOTAIR expression is correlated with the migration of RCC cells, and HOTAIR may be involved in the curcumin-induced inhibition of RCC metastasis.
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Performance and applications of flow-guided sieve trays for distillation of highly viscous mixtures
Hui Liu,Qun Shen Li,Chun Ying Song,Hai Long Wu,Yi Qiu Qian 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.6
With a particular focus on the distillation of highly viscous or self-polymerized mixtures, this study reports the hydrodynamic and mass transfer performance of two flow-guided sieve trays, including their pressure drop, entrainment, weeping and tray efficiency, obtained experimentally with an air-water/oxygen system in a Φ600 mm plexiglass column. The results show that the 8 mm hole flow-guided sieve tray tested shows better characteristics than the 7 mm flow-guided hole tray in terms of pressure drop and mass transfer. Then we present practical industrial examples of applications of the flow guided trays for distillation of viscous mixtures, i.e., the separation of vinyl acetate (VAC) from a polyvinyl acetate (PVAC) polymer solution with dynamic viscosity μ=50,000 mPas, the separation of highly unsaturated C5 mixtures by extractive distillation, and the distillation of thick, condensed and highly viscous fermentation mixtures made from fermented mash. It is demonstrated that flow-guided sieve trays with relatively large holes are an excellent candidate for distillation of mixtures with suspended solids, or concentrated/self-polymerized polymer solutions.
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Assessing the Impact of Advanced Technologies on Utilization Improvement of Substations
Dong Han,Zheng Yan,Dao-Tian Zhang,Yi-Qun Song 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.5
The smart substation is the heart of a transmission system, which is particularly emphasized as the most significant composition of smart grids in China. In order to assess the functionality performance of substation technologies, this paper presents methods used to identify the most promising solutions for smart substation design and to evaluate the technical levels of available technologies. The multi-index optimization model is presented to address the issue of smart substation planning. A mathematical model of the planning decision problem is established with multiple objectives consisting of economic, reliability, and green key indices, and many kinds of concerns including physical and environmentally friendly operations are formulated as a set of constraints. With respect to the assessment of the technical level regarding integration of advanced technologies into a substation, a modified grey whitenization weight function is adopted to structure a novel grey clustering method. The proposed grey clustering approach is used to overcome the difficulty of insufficient quantitative assessment capacity for traditional methods. The evaluation of technical effects provides the classification definition for the development phase and the maturity level of the smart substation. The effectiveness of the proposed approaches in planning decision-making and evaluation of construction efforts is demonstrated with case studies involving the actual smart substation projects of Wenchongkou substation in China Southern Power Grid (CSG) and Mengzi substation in State Grid Corporation of China (SGCC).
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Assessing the Impact of Advanced Technologies on Utilization Improvement of Substations
Han, Dong,Yan, Zheng,Zhang, Dao-Tian,Song, Yi-Qun The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.5
The smart substation is the heart of a transmission system, which is particularly emphasized as the most significant composition of smart grids in China. In order to assess the functionality performance of substation technologies, this paper presents methods used to identify the most promising solutions for smart substation design and to evaluate the technical levels of available technologies. The multi-index optimization model is presented to address the issue of smart substation planning. A mathematical model of the planning decision problem is established with multiple objectives consisting of economic, reliability, and green key indices, and many kinds of concerns including physical and environmentally friendly operations are formulated as a set of constraints. With respect to the assessment of the technical level regarding integration of advanced technologies into a substation, a modified grey whitenization weight function is adopted to structure a novel grey clustering method. The proposed grey clustering approach is used to overcome the difficulty of insufficient quantitative assessment capacity for traditional methods. The evaluation of technical effects provides the classification definition for the development phase and the maturity level of the smart substation. The effectiveness of the proposed approaches in planning decision-making and evaluation of construction efforts is demonstrated with case studies involving the actual smart substation projects of Wenchongkou substation in China Southern Power Grid (CSG) and Mengzi substation in State Grid Corporation of China (SGCC).
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