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무선 시스템의 안전한 전송을 위한 표준 End-To-End Security 플랫폼의 제안
임승채,김태연,오경희,정채영 조선대학교 기초과학연구소 2003 自然科學硏究 Vol.26 No.-
As various mobile service display a growth lease in a point of time that left an IMT-2000 commercialization near at hand. a security problem of wireless Internet environment is coming to the front by a large issue. A comparative analysis does security solution (WAP. ME. I-Mode) used for Data transmission on the wireless Internet in this paper and offers the platform which can solve an End-To-End Security problem. A proposed mobile authentication platform is the possibility suggest which can provide a safe mobile environment as a higher security level is provided, and stopping up effluence for me of plaintext with using a standardized encryption packet in WAP Gateway of the existing WAP.
김연하(Yeun-Ha Kim),김성중(Sung-Jung Kim),황호근(Ho-Geun Hwang),최석채(Suk-Chei Choi),김유림(Yu-Rim Kim),김경숙(Kyung-Suk Kim),김철(Chul Kim),최덕화(Deok-Hwa Choi),오정택(Jung-Taek Oh),김강득(Gang-Deuk Kim),김혜원(Hye-Won Kim),전창덕(C 대한해부학회 2004 Anatomy & Cell Biology Vol.37 No.2
염증성 장 질환의 병리기전에는 tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) 및 intracellular adhesion molecule-1 (ICAM-1)의 발현 등 수많은 염증반응의 매개 물질들이 관여하고 있다. Rebamipide는 위염과 위궤양 치료제로 개발된 약제로 아직까지 염증성 장 질환의 치료효과를 검증한 연구는 거의 없다. 따라서 본 연구에서는 Rebamipide의 염증성 장 질환에 대한 치료효과를 검증하고 그 기전을 분석하고자 Rebamipide의 TNF-α와 IL-1β, 그리고 세포의 부착에 중요한 역할을 하는 ICAM-1의 발현의 조절에 대한 효과를 조사하였다. 5%의 2, 4, 6-trinitrobenzenesulfonic acid (TNBS)를 실험 첫째날과 7일째에 직장 내로 넣어줌으로써 염증성 장질환의 동물모델을 제작하였고 2mM의 Rebamipide를 실험 0일, 3일, 6일째에 역시 직장 내로 투여하여 염증 억제 효과를 분석하였다. Rebamipide는 TNBS에 의하여 유도되는 체중감소를 현저히 억제하였으며 대장의 충혈과 부종역시 억제하였다. 조직소견에서도 Rebamipide 는 TNBS에 의해 유도되는 염증세포의 침착을 현저히 억제하였다. 또한 Rebamipide에 의해 TNF-α, IL-1β 및 ICAM-1의 발현 역시 현저히 억제되는 것을 면역 조직 화학 염색법을 통하여 확인하였다. 결론적으로 Rebamipide는 TNF-α, IL-1β와, ICAM-1의 발현을 조절함으로써 TNBS에 의해 유도되는 대장의 손상을 억제하리라고 생각되며 염증성 장 질환의 치료에도 좋은 효과가 있을 것으로 생각한다. During inflammation of the colon, cells of the gut mucosa produce or express numerous inflammatory mediators, such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and intercellular adhesion molecule 1 (ICAM-1). These mediators have been implicated as contributory factors to the inflammatory process, which results in colitis during inflammatory bowel disease (IBD). Rebamipide is an anti-gastric ulcer drug with anti-inflammatory properties in vivo and in vitro. The effects of Rebamipide on IBD have not been largely evaluated. Therefore, this study investigated the potential of Rebamipide to regulate the production of inflammatory mediators such as TNF-α, IL-1β, and ICAM-1. Mice with trinitrobenzene sulfonic acid (TNBS)-induced colitis (IBD animal model), were treated intrarectally with 2 mM Rebamipide. Body weight, macro- and micro-histological scores, and activity were evaluated. As an index of tissue edema, the thickness of the colonic wall was measured between the serosal surface and the luminal surface of the mucosa. TNF-α, IL-1β, and ICAM-1 were detected by immunohistochemical staining. Rebamipide treatment of mice exhibiting TNBS-induced colitis dramatically improved the clinical and histopathological findings of inflammation. In addition, Rebamipide suppressed TNF-α, IL-1β, and ICAM-1 expression in TNBS-treated animals. Taken together, these findings suggest that Rebamipide is a potential therapeutic agent for treating patients with IBD.
내막파열을 동반하지 않은 대동맥 박리 ( 대동맥 벽내출혈 ) 에 대한 임상적 고찰
황경국(Kyung Kuk Hwang),박대균(Dae Gyun Park),연태진(Tae Jin Yeun),조영석(Young Seok Cho),손대원(Dae Won Sohn),김효수(Hyo Soo Kim),김철호(Cheol Ho Kim),오병희(Byung Hee Oh),이명묵(Myoung Mook Lee),박영배(Young Bae Park),최윤식(Yun Sh 대한내과학회 1998 대한내과학회지 Vol.54 No.1
N/A Objectives: This study was performed to verify the incidence and prognosis of aortic dissection without intimal tear (aortic intramural hemorrhage, IMH) who took only medical treatment in special referrence to Stanford type A. Methods: We analysed the patients of IMH confirmed by TEE, CT, MRI, angiography or CT-angiography in Seoul National University Hospital between 1987 and l9%, retrospectively. Results: The diagnosis of IMH was estabilished in 20 of 143 patients(14%). Nine patients were Stanford type A, 11 patients were type B. The longitudinal extent varied between 8 and 30cm, and IMH size varied between 10 and 3mm. Surgery was performed in two of type A patients because of persistent chest pain and one of type B patients because of progressive aortic dilatation despite of medical treatment. Follow-up imaging studies (mean follow-up period of 20.0±22.0 months) were done in 10/17 patients who were treated medicaliy. Complete resolution of IMH was observed in seven cases, four of them were Stanford type A, and the mean size of IMH was 12mm(10-17mm). Partial resolution was observed in one case, Stanford type A, with the IMH size of 15mm. There was no significant change in the size of IMH in two cases. Initial mean size of IMH was 25mm. In no case, aortic rupture or death was observed during the follow up period. Conclusion: In the management of the patient with MH, same surgical indications as classic aortic dissection have been advocated based on similar prognosis. However our study showed better prognosis in IMH patients treated medically compared to the previous publications. Therefore, even in cases of proximal IMH. medical treatment should be seriously considered.
Hyun Kyung Bae,Yeun-Joo Lee,Keun Sang Park,Sung-Aeong Oh,Jong Tae Song,Hong Gyu Kang,Soon Ki Park 한국작물학회 2007 한국작물학회 학술발표대회 논문집 Vol.2007 No.11
The pollen grain is a unique tricellular structure suitable for the delivery of the sperm cells to the ovule. All nutrients required for microspore and pollen cell growth are derived by passage through the anther locule and secretion by the tapetum lining. During later stages the tapetum degenerates but contributes to produce pigments, waxes, lipids and proteins which form the pollen coat and function in signaling between male (pollen) and female (pistil) tissues. The development of both normal pollen and tapetum is necessary for the fertilization processes in rice and would be exploited for the induction of male-sterility which is very useful to improve economic value of crops. We aredeveloping new approaches using a conditional male-sterility for the F1 hybrid seed production in rice. The conventional three parental systems for F1 hybrid seed production requirethe following three lines: male-sterile line, maintainer line, and restorer line. In this system, a critical requirement is to maintain the male-sterile inbred lines. Here we suggest molecular approaches, in which the engineered male-sterile plants are generated by regulating endogenous hormonal balance through the loss-of-function of genes. We can expect the male-sterility can be restored by exogenous applications of hormones such as gibberellin or jasmonic acid. Based on two parental systems, we will address the answer onfollowing question: how can we maintain a male-sterile line producing 100% male-sterile progenies without a maintainer? This work was supported by grants from Crop Functional Genomics Center of the 21C Frontier Program (CG1517), RepublicKorea.
Jeon, Kyung-Won,Shim, Jae-Oh,Jang, Won-Jun,Lee, Da-We,Na, Hyun-Suk,Kim, Hak-Min,Lee, Yeol-Lim,Yoo, Seong-Yeun,Roh, Hyun-Seog,Jeon, Byong-Hun,Bae, Jong Wook,Ko, Chang Hyun Elsevier 2019 RENEWABLE ENERGY Vol.131 No.-
<P><B>Abstract</B></P> <P>In this study, a series of Ni−Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalysts, which were synthesized by co-precipitation followed by calcination at different temperatures, were applied for the deoxygenation of oleic acid. The physicochemical properties of the catalysts were characterized by N<SUB>2</SUB> adsorption-desorption, X-ray diffraction (XRD), H<SUB>2</SUB> chemisorption, H<SUB>2</SUB> temperature-programmed reduction (H<SUB>2</SUB>-TPR), NH<SUB>3</SUB> temperature-programmed desorption (NH<SUB>3</SUB>-TPD), and X-ray photoelectron spectroscopy (XPS). The Ni−Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalyst calcined at 300 °C exhibited the highest conversion for oleic acid as well as selectivity for diesel-range compounds. It is predominantly related to the highest amount of free NiO species. In addition, the acidity of the catalyst significantly affected the selectivity and distribution of products.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Calcination temperature influences the physicochemical properties of Ni–CZO. </LI> <LI> The Ni–CZO calcined at 300 °C exhibited the highest catalytic performance. </LI> <LI> Catalyst acidity significantly affected the selectivity and products distribution. </LI> <LI> Hence, the Ni–CZO is a promising for producing diesel-like hydrocarbons via DO. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>