白金錯物의 抗癌性에 對한 分子軌道論的 考察

呂煥鎭 慶北大學校 1984 論文集 Vol.37 No.-

Extened L.C.A.O.M.O. investigations in to the anticancer activity of platinum-complexes were carried out. Cis-Dichlorodiammine platinum (DDP) and its derivatives were successfully explained to have anticanccer activity but the trans-forms not to have. It has been found that the crystal field splitting of the cis-Pt complexes are narrower than that of the transforms, and the Pt-Cl bond strengths of cis-forms are weaker than that of the trans-forms. It could be belied that the cis-forms are more easily excited than the trans-forms, and the Pt-Cl bonds are easily breaking. It also found thau the bound beteen Pt-atom and Cl-atom in DDP molecules have jonic character, while Pt-N bond have covalent character. This means that the Cl-atom in DDp is easy to leave out as Cl^- in vivo. In Conclusions. It agress with experimental result that the species. <표 참조> combine to cellular component and interfere with the growth of cancer cell.

Stevens-Johnson 증후군: 증례보고 및 문헌고찰

여환호,김영균,서재훈 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.1

The Stevens-Johnson syndrome is a severe form of erythema multiforme associated with multiple organ involvement that can result in severe mortality. There are many etiologic factors including drugs, infection, or stress ; but accurate pathogenesis is still obscure. Treatments are composed of the removal of possible etiologic factors, symptomatic and supportive treatment. We experienced a case of Stevens-Johnson syndrome with involvement of generalized skin, oral mucosa, and eye involvement. This patient was treated by symptomatic and preventive method including corticostervid, antihystamine, and opthalmic treatment.

비안와 사골골절의 치료 : 증례보고

여환호,김영균 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

A naso-orbito- ethmoid(NOE) fracture is very complex diagnostically and therapeutically. The diagnosis of this fractures is usually made by physical findings aided by a CT scan. The primary treatment of NOE fracture must be directed toward the reconstruction of medial canthal ligament and bony skeleton. We prefer to correct lacrimal system abnormalities secondarily A 32-year old male patient visited emergency room of our hospital with NOE fracture. After emergency treatment and consultation with neurosurgery and ophthalmology, we treated this patient by performing reconstruction of medial canthal ligament, bone graft of media orbital rim bloeout fracture, and dorsal nasal cantilever bone graft with calvarial bone. The authors present a case report with literature review.

금속사출성형에 의한 중합금 소결체 부품 제조에 관한 연구

여환균,김병진,김길수,김성훈,송준호,한관희 嶺南大學校 工業技術硏究所 2003 工業技術硏究所論文集 Vol.31 No.2

In this study we demonstrate that a small complex part of a tungsten-based heavy alloy (W-Ni-Cu) can be readily manufactured by utilizing the metal injection molding (MIM) technology. We use a simple thermoplastic binder system, containing low density polyethylene, paraffin wax, and stearic acid. To remove the organic binder from the molded part, we employ the solvent extraction and thermal debinding processes. Densification of debound parts is achieved by sintering in hydrogen atmosphere. The experimental results of the optimization of process variables to manufacture the heavy alloy part are described, with a brief discussion.

신경섬유종증 환자의 외과적 치험 2례

여환호,안병후,김수관,김영균 大韓顎顔面成形再建外科學會 1992 Maxillofacial Plastic Reconstructive Surgery Vol.14 No.4

Tumors arising from nerve tissue are uncommon in the oral maxillofacial regions. Neurofibroma, a benign neurogenic tumor, can occur as circumscribed solitary or multiple lesions. A solitary neurofibroma is seldom undergo sarcomatous transformation, but fibromatosis is common. Therfore, it is important that we observe the oral and radiographic changes to help minimize the tremendous potential of the disease for facial disfigurement and altered function. The turmors were exised and there are no evidence of recurrence. The patients are satisfied with function and esthetic aspects.

有機및 無機發癌物質의 化學發癌性에 對한 分子軌道論的 硏究

呂煥鎭 慶北大學校 1981 論文集 Vol.31 No.-

The formation of a loosely bound molecular complex between chemical carcinogen and a cellular component was showned to be first step of Carcinogenesis. Assuming that some positions in the carcinogenic molecule play an important role in forming the molecular complex, the electron distribution of several organic precarcinogens and their metabolites was examined by means of HMO method. The results showed that the ability of accepting electrons at the two carbons of K-region and the atom of L-region in proximity of K-region increases with the proceeding of the metabolism that is in order of precarcinogen, proximate carcingen, ultimate carcinogen charged positively. Accordingly, the first step of Carcinogenesis is considered to be essential the formation of a positive ion as the result of metabolism. From this point of view, an attempt has been made to account for the carcinogenic activity of inorganic elements. It has been found as the result of comparison with experiments that a quantity named "excess polarizing strength" is qualified as good measure to predict the carcinogenic activity of inorganic elements. All elements which is above 0.22 in the value of "excess polarizing strength" have carcinogenic activity. The unified interpretation of the carcinogenicity of both organic compounds and inorganic elements may be possible on the assumption that the formation of molecular complex between a carcinogen and a cellular component is essential to the formation in the metabolism of positive ion in the body as an ultimate carcinogen.

매복된 하악 제3 대구치 발치시 항생제 투여의 효용성

여환호,박주철,정종훈,강태호 大韓顎顔面成形再建外科學會 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.4

To evaluate the efficacy of antibiotic administration in the impacted mandibular third molar extraction the author investigated 107 patients requiring extraction of the lower third molar who visited at the Department of oral and maxillofacial Surgery. Chosun Dental Hospital and were healthy without medical problems and had no signs and symptoms of infection around the lower third molar. The patients were divided into 4 groups according to the method of antibiotics administration : 13 patients without antibiotics administration(group 1), 30 patients with only intravenous injection of Cefazoline 2.0g 30 minutes before the procedure(group 2), 39 patients with intravenous injection of Cefazoline 2.0g 30 minutes before the procedure and oral administration of follow-up dosages of Augmentin for 1 day(group 3), and 25 aptients with intravenous injection of Cefazoline 2.0g 30 minutes before the procedure and oral administration of follow-up disages of Augmentin for 3 day(group 4). Infection rates after extraction wer calculated and compared according to gender, the age of the patients, the level of impaction, and also compared between four groups. The results were as follows. 1. The overall infection rate was 8.4%. 2. The infection rate was higher in male(11.9%) than in female(4.2%), but there were statistically no significant differences between them. 3. Infection rate was lower in patients under age 30(7.2%) than in patients over age 30(12.5%), but there were statistically no significant between them. 4. Infection rate was higher in patients with complete bony impacted tooth(11.1%) than in patients with partial bony impacted tooth(6.5%), but there were statistically no significant differences between them. 5. Infection rate was 7.7% in group 1, 10.0% in group 2, 10.3% in group 3, 4.0% ingroup 4 and there were statistically no significant differences between groups. In summary, it is more important to extract the impacted lower third molar under aseptic condition and to minimize the injury of tissue if possible than to administer the preventive antibiotics in reducing the infection rate in healthy patients without medical problems who had no signs and symptoms of infection around the lower third molar.

자기조절초점과 제품유형이 비교 광고 노출에 따른 소비자 반응에 미치는 영향

여준상,송환웅 한국방송광고공사 2007 광고연구 Vol.0 No.77

Although many researches addressed the effectiveness of comparative advertising, the results of comparative ad. effects compared to non-comparative ad. were mixed and the researches on the reason of this complexity were little. Thus, this research applied self-regulatory focus and hedonic-utilitarian framework which are discussed frequently in recent years to explore the moderating role on comparative ad. effects, and predicted that persuasion knowledge would play roles as a potential mediator. 2(type of ad.: non-comparative/comparative) × 2(regulatory focus: promotion/prevention) × 2(type of product: hedonic/utilitarian) between subjects ANOVA demonstrated supports for our predictions. In case of the interaction hypothesis between ad. type and regulatory focus, subjects in promotion focus condition activated little persuasion knowledge about comparative ad., so the difference of post-exposure attitude between non-comparative ad. and comparative ad. was little. However, subjects in prevention focus condition activated much persuasion knowledge about comparative ad., so the attitude after exposed to non-comparative ad. was more positive than comparative ad.. In case of the interaction hypothesis between ad. type and product type, subjects in hedonic product condition activated little persuasion knowledge about comparative ad., so the difference of post-exposure attitude between non-comparative ad. and comparative ad. was little. However, subjects in utilitarian product condition activated much persuasion knowledge about comparative ad., so the attitude after exposed to non-comparative ad. was more positive than comparative ad.. 비교 광고의 효과성에 대한 논의는 지속적으로 이루어져 왔지만 기존의 비교 광고 연구를 살펴보면 일반 광고와 비교 광고 간의 효과 차이에 대한 의견이 혼재되어 있으며, 그러한 혼재 이유에 대해 명확한 설명을 해주는 연구가 많지 않다. 이에 본 연구는 일반 광고와 비교 광고에 대한 반응에 있어 조절적 영향을 미치는 요인을 찾기 위해 최근 사회 심리학과 소비자 행동에서 많이 논의되고 있는‘자기조절초점(self-regulatory focus)’과‘쾌락(hedonic)-실용(utilitarian) 제품유형’을 적용하였으며, 결과를 설명해주는 잠재적 매개 변수로‘설득지식(persuasionknowledge: 상술지각)’을 예상하였다. 2(광고유형: 일반 광고/비교 광고) × 2(조절초점: 촉진/방어) × 2(제품유형: 실용/쾌락) 집단 간 디자인의 실험 결과, 대부분의 결과가 가설과 일치되는 방향성을 보였다. 구체적으로 살펴보면, 우선 광고유형과 조절초점 간 상호작용 가설의 경우, 촉진초점에서는 비교 광고에 대한 설득지식 활성화가 약하여 일반-비교 광고 간 소비자 반응(광고태도, 브랜드 태도)에 차이가 없으나 방어초점에서는 비교 광고에 대한 설득지식 활성화가 강하여 비교 광고에 비해 일반 광고 노출 후 소비자 반응이 더 좋게 나타났다. 그 다음으로 광고유형과 제품유형간 상호작용 가설의 경우, 쾌락적 제품에서는 비교 광고에 대한 설득지식 활성화가 약해 일반-비교 광고 간 소비자 반응에 유의한 차이가 없으나 실용적 제품에서는 비교 광고에 대한 설득지식 활성화가 강해 비교 광고에 비해 일반 광고에 노출되었을 때 소비자 반응이 더 좋게 나타났다.

대부도 및 제부도 연안해역 독립영양 부유생물군집의 생태학적 고찰

여환구 한서대학교 산학협력연구원 부설 환경연구소 1999 환경연구소 논문집 Vol.2 No.-

대부도 및 제부도 인근 해역에서 식물플랑크톤 군집구조의 파악을 위해 1996년 5월과 10월에 현장관측을 실시하였다. 연구해역의 식물플랑크톤 군집은 대체로 규조류 종들이 우점하였고 특히 Skeletonema costatum과 Parlia sulcata는 계속 우점하였다. 식물수문적 수역구분을 위해 시도한 집괴분석의 결과는 5월에는 특징적 양상이 보이지 않았으나 10월에는 육지에 인접한 수역과 바깥쪽 수역이 분리되었다. 한편 식물플랑크톤 군집의 종다양성지수는 5월에 1.98 - 2.54, 10월에는 1.91 - 2.53의 범위에 있었으며 대체로 2.0을 넘는 갑을 보였다. The structures of phytoplankton communities in the coastal waters of Taebudo and Jebudo were investigated two times, in May and October, 1996. Skeletonema costatum and Paralia sulcata, diatom species dominated in this study area continuously. The result of cluster analyses between the sampling stations didn't show characteristics in May, but the result in October showed seperated phytohydrographic regions, adjacent waters to the land and the waters far away from the land. Species diversities ranged from 1.98 to 2.53 in May and from 1.91 to 2.53 in October, and most of the values were higher than 2.0.

하악골 골절의 견고고정에 사용된 monocortical titanium miniplate와 관련된 감염증에 관한 연구

여환호,김영균,이효빈,김경원 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.4

Eighty-nine patients with mandibular fracture were treated by open reduction and internal fixation using the monocortical titanium miniplate(Leibinger Co.). Postsurgical intermaxillary fixation was carried out for 2 to 18 days according to the patient's status. Seven patients developed infections postoperatively(7.9%). Five patients were favorably treated by incision and drainage and/or saucerization. But two patients were not controlled by early surgical intervention and should have been followed by plate removal, saucerization and secondary reconstruction including the bone graft. This article reports the postoperative infection associated with miniplate fixation of mandibular fractures and discuss the incidence, cause, treatment and prognosis with careful case analyses.