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      • KCI등재

        魏晉寫槐骈赋研究

        Yang Mu Xiao,Yang Xiao Bin 한국중국산문학회 2013 중국산문연구집간 Vol.3 No.-

        홰나무를 소재로 한 변문은 위진시기 문인들에게 상당한 인기를 끌었으며 역대로 더욱 발전양상을 띄어 구식, 결구, 장법, 수사 등 여러 분야가 날로 성숙되었다. 홰나무에 대한 상징을 사용하는 일과 그 문화적 내함은 점차로 확립되어 당시의 심미관을 선명하게 체현하였다. 위진시기 홰나무 소재 변문 중 홰 나무 상징의 사용은 대략 세 가지 종류가 있다. 大槐安國(한 사람이 홰나무 밑에서 낮잠을 자다가 꿈에 대괴안국 왕의 사위가 되어 南柯郡을 20년 동안 다스리면서 부귀영화를 누리다가 꿈을 깨었다는 내용)의 정치적 우의, 槐社安民의 심리적 기탁, 그리고 槐仙之道의 현학적 함의이다. 일종의 상징 부호로서 홰나무는 위진시기에는 더 이상 자연지물에 대한 묘사는 아니었다. 부단한 전습과 변화로 다양한 측면의 인문 내함을 부여받게 되었고 농후한 역사적 연속성을 띄게 된 것이다.

      • rs10505474 and rs7837328 at 8q24 Cumulatively Confer Risk of Prostate Cancer in Northern Han Chinese

        Zhang, Lin-Lin,Sun, Liang,Zhu, Xiao-Quan,Xu, Yong,Yang, Kuo,Yang, Fan,Yang, Yi-Ge,Chen, Guo-Qiang,Fu, Ji-Cheng,Zheng, Chen-Guang,Li, Ying,Mu, Xiao-Qiu,Shi, Xiao-Hong,Zhao, Fan,Wang, Fei,Yang, Ze,Wang, Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Aims: Genome-wide association studies (GWAS) have identified several risk variants for prostate cancer (pCa) mainly in Europeans, which need to be further verified in other racial groups. We selected six previously identified variants as candidates and to define the association with PCa in Northern Han Chinese. Methods: 749 subjects from Beijing and Tianjin in Northern China were included. Six variants (rs10505474, rs7837328, rs4242384, rs7813, rs486907 and rs1058205) were genotyped by high resolution melting (HRM) assays. The individual and cumulative contribution for of the risk of PCa and clinical covariates were analyzed. Results: Among the six candidate variants, onlyrs10505474, and rs7837328, both locating at 8q24 region, were associated with PCa in our population.rs10505474 (A) was associated with PCa ($OR_{recessive}=1.56$, p=0.006); and rs7837328 (A) was associated with PCa ($OR_{dominant}=1.38$, p=0.042/$OR_{recessive}=1.99$, p=0.003). Moreover, we observed a cumulative effects between them ($p_{trend}=2.58{\times}10^{-5}$). The joint population attributable risk showed the two variants might account for 71.85% of PCa risk. In addition, we found the homozygotes of rs10505474 (A) and rs7837328 (A) were associated with PCa clinical covariants (age at onset, tumor stage, respectively) ($p_{age}=0.046$, $P_{tumorstage}=0.048$). Conclusion: rs10505474 (A) and rs7387328 (A) at 8q24 are associated with PCa and cumulatively confer risk, suggesting the two variations could determine susceptibility to PCa in the Northern Chinese Han population.

      • KCI등재

        Treatment performance and N2O emission in the UASB-A/O shortcut biological nitrogen removal system for landfill leachate at different salinity

        Mu Liu,Yongzhen Peng,Qing Yang,Tiantian Liu, Han Xiao,Shuying Wang 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.32 No.-

        Landfill leachate was treated using the upflow anaerobic sludge blanket (UASB) combined with anoxic/aerobic reactor (A/O) for shortcut biological nitrogen removal. The treatment performance and nitrousoxide (N2O) emission were studied under different salinity. When salinity increased from 10 to 35 g/L,the removal efficiency of ammonium nitrogen and total nitrogen decreased from 99.3 to 83.9% and from85.4 to 68.4%, respectively while the nitrite accumulation rate always remained high at more than 94.3%. The N2O conversion ratio increased by 14.7 times, from 0.3 to 4.7%. The concentration of biodegradableCOD in influent of the A/O reactor increased with the increase of salinity, which lead to the decrease ofdissolved oxygen and thus stimulated N2O emission remarkably during the aerobic zone. Meanwhile, theN2O emissions were likely to occur by a combination of pathways since the simultaneous nitritation anddenitritation was occurred in aerobic zone. The increase of NH4+-N concentration, NO2-N concentrationand pH caused by high salinity also promoted the N2O emission. The population of Nitrosomonaseuropaea increased with salinity, which was important for N2O emission.

      • KCI등재

        Establishment of a model to evaluate the nutritional quality of Bombyx mori Linnaeus (Lepidoptera, Bombycidae) pupae lipid based on principal components

        Yu-Xiao Zou,Teng-Gen Hu,Ying Shi,Jun Liu,Li-Xia Mu,Yang Xiao,Sen-Tai Liao 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.4

        Silkworm pupae are a source of edible lipid with a high content of unsaturated fatty acids (UFAs) (70% of total lipid content) and are becoming a focus of pharmaceutical and dietary research in the functional oil field. To study the nutritional value of different silkworm strains, principal component analysis (PCA) was used to establish a mathematical model and cluster analysis on silkworm pupae lipid (SPL) in 90 strains based on Z-score. Single-factor correlation analysis indicated that the PUFAs content was significantly positively correlated with the α-linolenic acid (ALA) (ρ=0.98) and negatively correlated with the oleic acid (OA) (ρ=−0.73) contents, and comprehensive of principal components mathematical model (PC =0.148ZX1 +0.00 2ZX2 −0.197ZX3 −0.338ZX4 +0.220ZX5 +0.304ZX6 +0.314ZX7, ZXi is the standard score (Z-score) of X1, which was calculated as follow: ZXi = (Xi −−X )/S, where X1: palmitic acid, X2: palmitoleic acid, X3: stearic acid, X4: OA, X5: linoleic acid, X6: ALA, X7: PUFAs.−X is the arithmetic mean content of variable i, and S is the standard deviation of variable i for all samples included in the analysis.) showed the amount of ALA and PUFAs were the key factors determining the nutritional value of the pupae lipid. Cluster analysis on the composite scores calculated by the model of the principal component divided the 90 strains into three groups. A cluster of 6 strains (XHR, XIFF, ZX, YT, YO and BTN) with the best nutritional value was characterized by high contents of ALA and PUFAs and a low content of oleic acid.

      • KCI등재

        Explore the dynamic alternation of gene PLAC4 mRNA expression levels in maternal plasma in second trimester for nonivasive detection of trisomy 21

        ( Lan Yang ),( Hai Yan Sun ),( Dao Zhen Chen ),( Mu Dan Lu ),( Ye Tang ),( Jian Pin Xiao ) 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.4

        Objective: Noninvasive prenatal detection of trisomy 21 (T21) has been achieved by measuring the ratio of two alleles of a single nucleotide polymorphism in circulating placenta specific 4 (PLAC4) mRNA in maternal plasma with a few assays in recent years. Our research is to explore the variations of PLAC4 mRNA expression level in maternal plasma with normal pregnancies in second trimester, which can provide pregnant women deeper insights with suitable detection period for the non-invasive prenatal detection of T21. Methods: We measured a serial plasma PLAC4 mRNA concentrations weekly from the same 25 singleton normal pregnant women. We recruited maternal plasma samples from 45 singleton pregnant women , comprising of 25 euploid pregnancies (control group; range, 17 to 21 weeks) and 20 T21 pregnancies (T21 group; range, 19 to 24 weeks). With the application of reverse transcription polymerase chain reaction, we achieved an insight of PLAC4 mRNA expression levels in maternal plasma during second trimester with euploid pregnancies. Results: Among the control group, the levels of PLAC4 mRNA expression in the gestation of 17 to 18 weeks were significantly less than those in the gestation of 18 to 21 weeks (P<0.05). The average PLAC4 mRNA concentration of the normal pregnant women was not higher than that of the T21 group (P>0.05). Conclusion: The PLAC4 mRNA showed a higher level of expression in the gestation of 18 to 21 weeks with an euploid pregnancy of pregnant women. We also found that there was no significant difference in plasma PLAC4 mRNA concentration between the normal and the T21 pregnancies in second trimester.

      • KCI등재

        Containment Control of Continuous-time Multi-agent Systems with General Linear Dynamics under Time-varying Communication TopologiesTopologies

        Zhe Yang,Xiao-wu Mu,Kai Liu 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1

        This paper devotes itself to the containment tracking problem of general linear high-order multiagentsystems (MASs) under time-varying communications. For general linear MASs with time-varying weightunbalanceddigraph, the containment control problem is difficult and challenging, because the Lyapunov methodis not an effective approach in this case. Under the assumption that the graph topology uniformly and jointlyhas a directed spanning forest, we show that when the exponentially unstable mode associated with each agent’sself-dynamics is weak enough, the followers can asymptotically tend to the dynamical convex hull spanned bythe leaders, i.e. the containment can be achieved. Moreover, the least convergence rate is explicitly specified. Simulations are also provided to demonstrate the effectiveness of our result.

      • KCI등재

        AUV hull lines optimization with uncertainty parameters based on six sigma reliability design

        Yuan hang Hou,Xiao Liang,Xu yang Mu 대한조선학회 2018 International Journal of Naval Architecture and Oc Vol.10 No.4

        Autonomous Underwater Vehicle (AUV), which are becoming more and more important in ocean exploitation tasks, needs energy conservation urgently when sailing the complex mission path in long time cruise. As hull lines optimization design becomes the key factor, which closely related with resistance, in AUV preliminary design stage, uncertainty parameters need to be considered seriously. In this research, Myring axial symmetry revolution body with parameterized expression is assumed as AUV hull lines, and its travelling resistance is obtained via modified DATCOM formula. The problems of AUV hull lines design for the minimum travelling resistance with uncertain parameters are studied. Based on reliability-based optimization design technology, Design For Six Sigma (DFSS) for high quality level is conducted, and is proved more reliability for the actual environment disturbance.

      • KCI등재

        Alu Tandem Sequences Inhibit GFP Gene Expression by Triggering Chromatin Wrapping

        Xiu Fang Wang,Xiao Yan Wang,Jing Liu,Jing Jing Feng,Wen Li Mu,Xiao Juan Shi,Qin Qing Yang,Xiao Cui Duan,Ying Xie,Zhan Jun Lu 한국유전학회 2009 Genes & Genomics Vol.31 No.3

        Alu elements belonging to the short interspersed nuclear elements (SINE) of repetitive elements are present in more than one million copies which altogether represent 10% of the whole human genome. In this study, the roles of Alu tandem sequences in the process of GFP gene (GFP) expression and packing into chromatin of its DNA were studied. To detect the effect of Alu repeats on gene expression, different copies of Alus were inserted GFP downstream respectively in pEGFP-C1 vector. We found that Alu sequences decreased the amount of GFP transcription, the percentage of GFP positive cells and the accessibility to DNase I in length-dependent manner. Inserting Alu caused the production of higher-molecular-mass RNA, indicating Alu sequence did not induce premature transcriptional termination. Tight packing chromatins keep silent and resist to DNase I digestion, which is a general phenomenon. We suggested that head and tail tandem Alu sequences suppressed GFP expression in length dependent manner by triggering chromatin packing.

      • Upregulation of MicroRNA 181c Expression in Gastric Cancer Tissues and Plasma

        Cui, Mei-Hua,Hou, Xiao-Lin,Lei, Xiao-Yan,Mu, Fang-Hong,Yang, Gui-Bin,Yue, Lin,Fu, Yi,Yi, Guo-Xing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Objective: To test the microRNA-181c (miR-181c) expression in tissues and plasma of gastric cancer (GC) cases, analyze any correlations, and explore the possibility of miR-181c as a potential molecular marker for GC diagnosis. Materials and Methods: Relative miR-181c expression levels in cancers and plasma from 30 GC patients was tested using reverse transcription-real-time fluorescent quantitation PCR and compared to that in samples from 30 gastric ulcer and 30 chronic gastritis patients. Results: The miR-181c expression level in the GC tissues was significantly higher than that in the gastric ulcer and chronic gastritis tissues (P = 0.000), as was the miR-181c expression level in the GC plasma (P = 0.000). We determined that miR-181c expression in GC plasma was positively correlated to its expression in the GC tissues (P = 0.000). Conclusions: The expression of miR-181c is upregulated in GC tissues and plasma, and the miR-181c expression level in GC plasma is positively correlated to that in the corresponding cancer tissues. Plasma miR-181c is possibly a new serological marker for GC diagnosis.

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