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Association Between the hsa-mir-27a Variant and Breast Cancer Risk: a Meta-analysis
Wang, Bin,Ma, Ning,Wang, Yajie Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
Introduction: Although a number of studies were published in the past several years on associations between hsa-mir-27a and cancer risk, the findings remain conflicting rather than conclusive. To derive a more precise effect on the association between SNP hsa-mir-27a rs895819 and breast cancer risk, we conducted a meta-analysis for the first time. Materials and Methods: Through retrieval from PubMed for the period up to August 2012, a total of four studies were identified with 3,287 cases and 4,298 controls for SNP hsa-mir-27a rs895819. We calculated summary odds ratio (ORs) and corresponding 95% confidence intervals (CIs) using a fixed effects model (when the heterogeneity was absent, P>0.10). Otherwise, the random-effects model was used. Results: We found that hsa-mir-27a rs895819 polymorphism also did not reveal any relationship with breast cancer susceptibility (AG versus AA: OR = 0.98; 95%CI, 0.73-1.32; GG versus AA: OR = 0.86; 95% CI, 0.72-1.03; AG/GG versus AA: OR = 0.92; 95% CI, 0.74-1.14), while significantly decreased risk was found among Europeans in AG versus AA and AG/GG versus AA models tested (AG versus AA: OR = 0.83; 95%CI, 0.72-0.97; GG versus AA: OR = 0.86; 95% CI, 0.71-1.05; AG/GG versus AA: OR = 0.84; 95% CI, 0.75-0.94). Conclusion: These findings suggest that hsa-mir-27a rs895819 polymorphism may play an important role in breast cancer development.
Structure and Electrical Performance of Na<sub>2</sub>C<sub>6</sub>O<sub>6</sub> under High Pressure
Wang, Xuan,Zhang, Peijie,Tang, Xingyu,Guan, Junjie,Lin, Xiaohuan,Wang, Yajie,Dong, Xiao,Yue, Binbin,Yan, Jinyuan,Li, Kuo,Zheng, Haiyan,Mao, Ho-kwang American Chemical Society 2019 The Journal of Physical Chemistry Part C Vol. No.
<P>Sodium rhodizonate (Na<SUB>2</SUB>C<SUB>6</SUB>O<SUB>6</SUB>) has very high theoretical capacity as a positive electrode material of sodium-ion batteries, but it still has problems such as low actual capacity and poor electronic/ionic conductivity. In order to improve its conductivity, we investigated its structure and electrical properties under high pressure. By performing in situ X-ray diffraction, Raman, infrared absorption, and alternating current impedance spectroscopy in the range of 0-30 GPa at room temperature, we observed a phase transition at ∼11 GPa, with the conductivity increasing by an order of magnitude. Above ∼20 GPa, Na<SUB>2</SUB>C<SUB>6</SUB>O<SUB>6</SUB> gradually amorphized. During the decompression process, the pressure regulation of the structure and properties of the material are reversible. Our study shows that applying external pressure is an effective tool to improve the conductivity of molecular battery materials. The investigation will help to obtain next-generation electrode materials.</P> [FIG OMISSION]</BR>
Type synthesis of 3T2R decoupled hybrid mechanisms with large bearing capacity
Sen Wang,Shihua Li,Haoran Li,Yajie Zhou,Yongjie Wang,Xinyu Wang 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.4
This paper proposes a new synthesis method of three translational and two rotational (3T2R) decoupled hybrid mechanism with large bearing capacity, based on the screw theory and the atlas method. According to the degree of freedom and decoupled characteristics of the 3T and 2R mechanisms, the decoupled conditions for the 3T and 2R parallel mechanisms are proposed. The optimal conditions for the motion/force transmission performance of the 3T decoupled parallel mechanisms with redundant actuation is presented. A redundant actuated limb construction method is proposed to improve the load capacity of the hybrid mechanism. Following the design steps of the fully decoupled hybrid mechanism, 3T2R hybrid mechanisms with large load capacity are obtained. Kinematics and statics analysis verify the correctness of the proposed synthesis method. The mechanism synthesized by this method has a good application prospect in large load occasion.
Thermal behavior study and experimental testing of deep groove ball bearings
Shuzhi Gao,Yajie Wang,Yimin Zhang 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.12
In this study, based on the experimental analysis of heat generation in deep groove ball bearings, the thermal nodes about the deep groove ball bearings is established by using heat network method. The temperature field of the bearing is simulated with finite element software, and the result obtained from the simulation is in good agreement with the comparison of the theoretical calculation results. The bearing test bench was used to analyze the bearing, and the experimental results again proved the effectiveness of the thermal network method. It was found that the bearing speed played a significant role in the working temperature of a bearing, which was consistent to the analysis of the thermal network method, verifying the feasibility of the thermal network method to solve bearing temperature, laying the foundation for the subsequent research on the heat transfer law of motor and rolling bearing.
Xiaomeng Chen,Yajie Wang,Yu Gao,Tongguo Gao,Dongdong Zhang 한국식물병리학회 2019 Plant Pathology Journal Vol.35 No.5
Botrytis cinerea, a major phytopathogenic fungus, has been reported to infect more than 200 crop species worldwide, and it causes massive losses in yield. The aim of this study was to evaluate the inhibitory abilities and effects of Bacillus amyloliquefaciens RS-25, Bacillus licheniformis MG-4, Bacillus subtilis Z-14, and Bacillus subtilis Pnf-4 and their culture filtrates and extracts against the gray mold caused by B. cinerea on postharvest tomato, strawberry, and grapefruit. The results revealed that the cells of Z-14, culture filtrate of RS- 25, and cells of Z-14 showed the strongest biocontrol activity against the gray mold on the strawberry, grape, and tomato fruit, respectively. All the strains produced volatile organic compounds (VOCs), and the VOCs of Pnf-4 displayed the highest inhibition values. Based on headspace solid-phase microextraction in combination with gas chromatography-mass spectrometry, esters accounted for the largest percentage of the VOCs produced by RS-25, MG-4, Z-14, and Pnf-4 (36.80%, 29.58%, 30.78%, and 36.26%, respectively). All the strains showed potent cellulase and protease activities, but no chitinase activity. RS-25, Z-14, and MG-4, but not Pnf-4, grew on chrome azurol S agar, and an orange halo was formed around the colonies. All the strains showed biofilm formation, fruit colonization, and lipopeptide production, which may be the main modes of action of the antagonists against B. cinerea on the fruit. This study provides the basis for developing natural biocontrol agents against the gray mold caused by B. cinerea on postharvest fruit.
Chen, Xiaomeng,Wang, Yajie,Gao, Yu,Gao, Tongguo,Zhang, Dongdong The Korean Society of Plant Pathology 2019 Plant Pathology Journal Vol.35 No.5
Botrytis cinerea, a major phytopathogenic fungus, has been reported to infect more than 200 crop species worldwide, and it causes massive losses in yield. The aim of this study was to evaluate the inhibitory abilities and effects of Bacillus amyloliquefaciens RS-25, Bacillus licheniformis MG-4, Bacillus subtilis Z-14, and Bacillus subtilis Pnf-4 and their culture filtrates and extracts against the gray mold caused by B. cinerea on postharvest tomato, strawberry, and grapefruit. The results revealed that the cells of Z-14, culture filtrate of RS-25, and cells of Z-14 showed the strongest biocontrol activity against the gray mold on the strawberry, grape, and tomato fruit, respectively. All the strains produced volatile organic compounds (VOCs), and the VOCs of Pnf-4 displayed the highest inhibition values. Based on headspace solid-phase microextraction in combination with gas chromatography-mass spectrometry, esters accounted for the largest percentage of the VOCs produced by RS-25, MG-4, Z-14, and Pnf-4 (36.80%, 29.58%, 30.78%, and 36.26%, respectively). All the strains showed potent cellulase and protease activities, but no chitinase activity. RS-25, Z-14, and MG-4, but not Pnf-4, grew on chrome azurol S agar, and an orange halo was formed around the colonies. All the strains showed biofilm formation, fruit colonization, and lipopeptide production, which may be the main modes of action of the antagonists against B. cinerea on the fruit. This study provides the basis for developing natural biocontrol agents against the gray mold caused by B. cinerea on postharvest fruit.
Yana Li,Xianhua Hou,Yajie Li,Qiang Ru,Shaofeng Wang,Shejun Hu,Kwok-ho Lam 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.5
Hierarchical CoMn2O4 microspheres assembled bynanoparticles have been successfully synthesized by afacile hydrothermal method and a subsequent annealingtreatment. XRD detection indicate the crystal structure. SEM and TEM results reveal the 3-dimensional porousand micro-/nanostructural microsphere assembled bynanoparticles with a size of 20-100 nm. The CoMn2O4electrode show initial specific discharge capacity ofapproximately 1546 mAh/g at the current rates 100 mA/gwith a coulombic efficiency of 66.7% and remarkablespecific capacities (1029-485 mAh/g) at various currentrates (100-2800 mA/g).
Kaili Zhu,Hongsheng Tan,Yajie Wang,Changheng Liu,Xiaomin Ma,Jie Wang,Haini Xing 한국섬유공학회 2019 Fibers and polymers Vol.20 No.4
The effect of two different continuous carbon fibers (CCF1 and CCF2) with different material properties onstructure-properties of continuous carbon fibers reinforced polyether-ether-ketone prepreg tapes (CCF/PEEKPT) prepared bya wet powder impregnation process were investigated. The effects of fiber content on the tensile properties, dynamicmechanical behavior, crystallization melting behavior and fracture morphology of prepared prepreg tapes were performed bythe dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC) and scanning electron microscope (SEM)etc. The results showed that, the tensile strength of CCF1/PEEKPT increased with increasing of the carbon fiber contentwithin 50-75 wt%. Meanwhile, the tensile strength of 50-65 wt% CCF2/PEEKPT had the same change trend, but thendecreased when the fiber content of composites was higher than 65 wt%. The storage modulus (E′) of composites increasedwith adding content of carbon fiber. The composites still maintained high deformation resistance when the temperature roseto 290 oC. Compared with pure PEEK, the crystallinity and crystallization rate of the composites both increased with theoccurrence of fiber inducing PEEK crystallization, but the crystallization onset temperature, crystallization temperature andmelting temperature of CCF/PEEKPT moved to low temperatures with adding of fiber content. In general, these observationssuggested that CCF hindered the movement of the polymer chain segment and constrained the spherulites growth of PEEKfor CCF/PEEKPT.