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Xu Kai,Liu Lin,Li Wenhui,Sun Xiaoqing,Shen Tongxu,Pan Feng,Jiang Yuqing,Guo Yan,Ding Lei,Zhang Mengchao 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.6
Objective: The presence of coagulative necrosis (CN) in clear cell renal cell carcinoma (ccRCC) indicates a poor prognosis, while the absence of CN indicates a good prognosis. The purpose of this study was to build and validate a radiomics signature based on preoperative CT imaging data to estimate CN status in ccRCC. Materials and Methods: Altogether, 105 patients with pathologically confirmed ccRCC were retrospectively enrolled in this study and then divided into training (n = 72) and validation (n = 33) sets. Thereafter, 385 radiomics features were extracted from the three-dimensional volumes of interest of each tumor, and 10 traditional features were assessed by two experienced radiologists using triple-phase CT-enhanced images. A multivariate logistic regression algorithm was used to build the radiomics score and traditional predictors in the training set, and their performance was assessed and then tested in the validation set. The radiomics signature to distinguish CN status was then developed by incorporating the radiomics score and the selected traditional predictors. The receiver operating characteristic (ROC) curve was plotted to evaluate the predictive performance. Results: The area under the ROC curve (AUC) of the radiomics score, which consisted of 7 radiomics features, was 0.855 in the training set and 0.885 in the validation set. The AUC of the traditional predictor, which consisted of 2 traditional features, was 0.843 in the training set and 0.858 in the validation set. The radiomics signature showed the best performance with an AUC of 0.942 in the training set, which was then confirmed with an AUC of 0.969 in the validation set. Conclusion: The CT-based radiomics signature that incorporated radiomics and traditional features has the potential to be used as a non-invasive tool for preoperative prediction of CN in ccRCC.
Big Data Acquisition and Analysis Platform for Intermodal Transport
Kai Xu,Hong Zhen,Yan Li,Luo Yue 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.12
This paper aims for the transparency and visualization of the international intermodal cargo transportation throughout its whole process, achieving a comprehensive monitoring on the multiple transportation means such as by ocean, by air, by land or by rail. Based on Internet-of-Things-based distributed data acquisition technology and the cloud-computing-based big data analysis technology, this paper gives out a Multimodal Monitoring technology that can uniformly solve the comprehensive management of multiple transportation vehicles, which includes a service functionality model, a network hierarchy model and a technology system model. By building a Generic Target Monitoring System, it proves the multimodal monitoring resolution is able to effectively monitor the multiple transportation means and provide a fair good database platform of later analysis, distribution and optimization of those vehicles.
Xu, Jia,Liu, Chang,Zhou, Lei,Tian, Feng,Tai, Ming-Hui,Wei, Ji-Chao,Qu, Kai,Meng, Fan-Di,Zhang, Ling-Qiang,Wang, Zhi-Xin,Zhang, Jing-Yao,Chang, Hu-Lin,Liu, Si-Nan,Xu, Xin-Shen,Song, Yan-Zhou,Liu, Jun,Z Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Serum alpha-fetoprotein (AFP) is a significant marker for clinical diagnosis and prognosis evaluation in hepatocellular carcinoma (HCC) patients. However, some proportion of liver cancer patients are AFP-negative (AFP ${\leq}$20ng/ml). In order to study the differences between clinicopathological factors and prognosis of alpha-fetoprotein negative and positive patients, a total of 114 cases (41 AFP-negative and 73 AFP-positive) were selected for our research. By systematically statistical analysis, the results demonstrated that compared with AFP-negative patients, AFP-positive examples were more likely to feature cirrhosis nodules, non-complete neoplasm capsules, and a poor Edmondson-steiner grade. Furthermore, AFP-negative patients demonstrated a favorable long-term prognosis. By univariate analysis and multivariate analysis with Cox's proportional hazards model, multiple tumors were found to be independent risk factors for worse survival of AFP negative patients; however, less tumor-free margins, multiple tumors and Edmondson-steiner grades III/IV, proved to be independent risk factors leading to a poor prognosis of AFP positive cases. Finally, we can infer that high levels of AFP signify a highly malignant tumor and unfavorable prognosis.
Kai Xu,Zhenchang Tang,Yan Zhang,Wanshu Li,Haiou Li,Lihui Wang,Li-Ming Liu,Hong-Hang Wang,Feng Chi,Xiaowen Zhang 한국물리학회 2019 Current Applied Physics Vol.19 No.10
Germanium dioxide (GeO2) aqueous solutions are facilely prepared and the corresponding anode buffer layers (ABLs) with solution process are demonstrated. Atomic force microscopy, X-ray photoelectron spectroscopy and ultraviolet photoelectron spectroscopy measurements show that solution-processed GeO2 behaves superior film morphology and enhanced work function. Using GeO2 as ABL of organic light-emitting diodes (OLEDs), the visible device with tris(8-hydroxy-quinolinato)aluminium as emitter gives maximum luminous efficiency of 6.5 cd/A and power efficiency of 3.5 lm/W, the ultraviolet device with 3-(4-biphenyl)-4-phenyl-5-tert-butylphenyl- 1,2,4-triazole as emitter exhibits short-wavelength emission with peak of 376 nm, full-width at halfmaximum of 42 nm, maximum radiance of 3.36 mW/cm2 and external quantum efficiency of 1.5%. The performances are almost comparable to the counterparts with poly (3,4-ethylenedioxythiophene):poly (styrenesulfonate) as ABL. The current, impedance, phase and capacitance as a function of voltage characteristics elucidate that the GeO2 ABL formed from appropriate concentration of GeO2 aqueous solution favors hole injection enhancement and accordingly promoting device performance.
Surface nanocrystallization and its properties of a rare earth magnesium alloy induced by HVOF―SMB
Kai-dong Xu,Ji-na Wang,Ai-hua Wang,Hua Yan,Xiang-lin Zhang,Zao-wen Huang 한국물리학회 2011 Current Applied Physics Vol.11 No.3
The nanocrystalline microstructure in the surface of a rare earth magnesium alloy induced by a new process named HVOF―SMB (high velocity oxygen-fuel flame supersonic microparticles bombarding) has been characterized by means of X-ray diffractometry (XRD) and high-resolution transmission electron microscopy (HRTEM). The effects of HVOF―SMB on mechanical properties and corrosion resistance of the magnesium alloy have been investigated by microhardness distribution and polarization curves, and the cross-sectional observation of the treated Mg alloy sample has been characterized by optical microscopy (OM). Results showed that HVOF―SMB can induce surface nanocrystallization with a grain size level less than 20 nm at topmost surface layer, and the microhardness at the top surface layer increases up to about 170 HV_0.025 which is twice more than that of the substrate. The grain size increases as well as the microhardness decreases gradually with the depth varying from surface to substrate. The potentiodynamic polarization curves indicate that the HVOF―SMB treated surfaces show lower corrosion resistance in comparison with the untreated magnesium alloy in 3.5% NaCl solution. The underlying mechanism of the electrochemical properties on the nanocrystalline Mg-based alloy’s surface induced by severe plastic deformation in corrosion resistance is discussed.
New functional glasses containing semiconductor quantum dots
Xu, Kai,Heo, Jong Royal Swedish Academy of Sciences 2010 Physica scripta Vol.2010 No.t139
<P>CdSe and PbSe quantum dots (QDs) were precipitated in oxide glass matrices and their optical properties were investigated. The size of QDs could be controlled using careful heat treatment. The quantum confinement effect was clearly observed, as evidenced by a shift in the peak wavelengths of absorption. It was possible to control also the wavelength of the photoluminescence bands of CdSe and PbSe QDs by using thermal treatment.</P>
Kai Xu,Ping Hong,Lijun Luo,Tao Xia 한국식물학회 2009 Journal of Plant Biology Vol.52 No.5
PlantNa+/H+ antiporter plays a critical role in plant salt tolerance. In this study, AtNHX1, a vacuolar Na+ /H+ antiporter from Arabidopsis thalina, was introduced into Petunia hybrida using Agrobacterium-mediated methods. Polymerase chain reaction (PCR) and DNA gel blot analysis confirmed that AtNHX1 was successfully integrated into the P. hybrida genomes. Reverse transcription (RT)-PCR analysis indicated that AtNHX1 expressed highly in transgenic plants. It was found that the 35S::AtNHX1 transgenic P. hybrida plants showed much more resistant to high concentrations of NaCl and to water deprivation than the isogenic wild-type (WT) Petunia plants. The transgenic plants accumulated more Na+, K+, and proline in their leaf tissue than that of the WT Petunia plants and maintained high water contents and high ratio of K+/Na+. These results demonstrated that overexpression of the vacuolar Na+/H+ antiporter conferred both salt tolerance and drought tolerance to the transgenic Petunia plants.